| 301. | How Every Movie & Video Game Tricks Your Brain | 24,099 | |
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| 302. | What's The Most Successful Species on Earth? | 24,357 | |
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| 303. | What's the Largest Living Thing On Earth? | 24,380 | |
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| 304. | Is Big Data Getting Too Big? | 24,778 | |
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| 305. | How Did We Figure Out What Light Is? | 25,513 | |
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| 306. | Climate Science: What You Need To Know | 25,524 | |
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| 307. | The Science of Farts | 25,671 | |
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| 308. | Are You Smarter Than A Slime Mold? | 25,965 | |
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| 309. | Why Don't Other Animals Wear Glasses? | 26,084 | |
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| 310. | Are You Afraid of Holes? | 26,090 | |
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| 311. | There's Proof of Evolution Hiding in Your DNA | 26,119 | |
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| 312. | Using a Bunch of Mousetraps to Explain How Pandemics Work (feat. @theslowmoguys) | 26,240 | |
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| 313. | Is Earth's Most Important Ocean Current Doomed? | 26,380 | |
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| 314. | Why Don't Big Animals Get More Cancer? | 26,418 | |
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| 315. | I Can't Believe We're Making Another COVID Video | 26,672 | |
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| 316. | Why Are Cicadas So Good At Math? | 26,777 | |
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| 317. | DNA Doesn’t Look Like What You Think! | 27,058 | |
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| 318. | How To See Colors That Aren't Real | 27,353 | |
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| 319. | What’s REALLY Warming the Earth? | 27,403 | |
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| 320. | Has AI Surpassed Human Creativity? | 70,000 | |
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| 321. | Is There Intelligent Life On Other Planets? | 27,453 | |
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| 322. | CRISPR and the Future of Human Evolution | 27,561 | |
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| 323. | 4 Ways the Universe Might End (All of Them Are Bad) | 27,957 | |
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| 324. | Why the Plastic Pollution Problem Is So Much Worse Than You Think | 28,025 | |
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| 325. | How The Placebo Effect Tricks Your Brain | 28,046 | |
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| 326. | Why Do We Cry? | 28,077 | |
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| 327. | Sunlight Is Way Older Than You Think. Here’s Why… | 28,292 | |
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| 328. | Why Don't Birds Lay Square Eggs? | 28,389 | |
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| 329. | What If There Were No Sharks? | 28,445 | |
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| 330. | A Brief History Of (Keeping) Time | 28,811 | |
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| 331. | How Some Animals Engineered Air Conditioning | 29,077 | |
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| 332. | Why Seasons Make No Sense | 29,237 | |
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| 333. | Could You Be a Chimera? | 29,359 | |
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| 334. | What’s The Hottest Hot and Coldest Cold? | 29,514 | |
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| 335. | The Mathematical Code Hidden In Nature | 29,952 | |
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| 336. | What Is Luck? | 30,003 | |
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| 337. | Why Do We Cook? | 30,335 | |
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| 338. | Could You Ever Be Immune To EVERY Disease? Your Immune System, Explained! | 30,872 | |
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| 339. | The Surprising Species That Everything Else Depends On | IN OUR NATURE | 30,884 | |
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| 340. | Why Are Some People Left-Handed? | 31,842 | |
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| 341. | How These Ants Took Over the U.S. 🔥🔥🔥🔥🔥 | 31,995 | |
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| 342. | There's No Such Thing As Cold | 32,464 | |
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| 343. | Why Does Hair Grow The Way It Does? | 32,687 | |
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| 344. | Trying to Land a Plane (to Prove the Dunning-Kruger Effect) | 32,770 | |
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| 345. | The Science of Game of Thrones | 32,773 | |
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| 346. | How Habits Can Change Your Life (and Your Brain) | 33,812 | |
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| 347. | Why the Heck Are We Ticklish? | 33,935 | |
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| 348. | What If We Could See Nature In Infrared? | 34,772 | |
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| 349. | Can Life Really Be Explained By Physics? (featuring Prof. Brian Cox) | 35,140 | |
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| 350. | How to Figure Out the Day of the Week For Any Date Ever | 35,400 | Guide |
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| 351. | Is Ultron Inevitable? Featuring Vsauce3! | 35,505 | |
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| 352. | Why People Don't Believe In Climate Science | 35,805 | Vlog |
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| 353. | Do Plants Think? | 35,897 | Vlog |
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| 354. | If We Plant 1 TRILLION Trees Can We Stop Climate Change? | 35,933 | |
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| 355. | 6 Chemical Reactions That Changed History | 36,954 | |
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| 356. | Your Salad Is Trying To Kill You | 37,156 | |
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| 357. | Does My Dog Know What I'm Thinking? | 37,554 | |
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| 358. | Did Dinosaurs Really Go Extinct? | 37,582 | |
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| 359. | Why No One Can Agree What’s REALLY the Tallest Mountain | 37,651 | |
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| 360. | Fact vs. Theory vs. Hypothesis vs. Law… EXPLAINED! | 37,775 | |
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| 361. | Is Santa Real? (A Scientific Analysis) | 37,787 | |
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| 362. | What Do Raindrops Really Look Like? | 37,988 | |
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| 363. | The Oldest Living Things In The World | 37,999 | |
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| 364. | Fixing Daylight Saving Time Is THIS Easy | 38,017 | |
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| 365. | Who Invented the Metric System (and Why It Isn’t As Perfect as You Think) | 38,095 | |
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| 366. | Why BEAVERS Are The Smartest Thing In Fur Pants | 38,629 | |
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| 367. | How Did Giant Pterosaurs Fly? | 38,933 | |
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| 368. | Is Space a Thing? | 38,946 | |
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| 369. | Do Fish Pee? | 39,397 | |
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| 370. | COVID-19 & Mask Myths DEBUNKED! | 39,493 | |
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| 371. | Why Do You Love Your Family? | 39,712 | |
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| 372. | Why You Can’t Smell Yourself (and Other Ways Your Senses Lie to You) | 39,800 | |
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| 373. | Why Do We Laugh? | 40,207 | |
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| 374. | The Surprising Reason We Eat Spicy Food | 41,514 | |
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| 375. | Is Your Brain Too Old For Video Games? | 41,824 | | StarCraft II
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| 376. | What Is Nothing? | 42,439 | |
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| 377. | The Science of Marathon Running | 43,356 | Vlog |
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| 378. | The Largest River On Earth Is In The Sky | 43,778 | |
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| 379. | How Much Of You Is ACTUALLY Alive? | 43,995 | |
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| 380. | How to Defuse the Overpopulation Bomb | 44,387 | |
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| 381. | Why Don’t Woodpeckers Get Concussions? | 44,390 | |
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| 382. | Why Don't Ants Get Stuck In Traffic? | 44,753 | |
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| 383. | How Your Brain Makes Time Pass Fast or Slow | 45,135 | |
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| 384. | Where Did Humans Come From? | 45,586 | |
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| 385. | TRILLIONS of cicadas are emerging. Math can tell us why… | 197,000 | |
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| 386. | Glass is Solid… So Why Is It Clear? | 45,793 | |
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| 387. | How The Toilet Changed History | 46,417 | |
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| 388. | Why Do More Species Live Near the Equator? | 46,901 | |
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| 389. | What is Déjà Vu?! | 48,240 | |
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| 390. | The 12 Days of Evolution - Complete Series! | 48,911 | |
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| 391. | The INCREDIBLE Ancient Engineering That Built the Pyramids | 48,956 | |
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| 392. | Is Sugar a Drug? | 49,660 | |
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| 393. | Could You REALLY Survive Being Shrunk?! | 49,704 | |
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| 394. | Probably the worst idea in the history of the space age | 173,000 | |
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| 395. | Why Do We Lie? | 50,254 | |
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| 396. | The Strange and Unexpected Reason Ice is Slippery | 50,301 | |
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| 397. | Here's What I Learned From Getting COVID | 52,188 | |
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| 398. | How Blind People See With Sound… with @MollyBurkeOfficial! | 52,647 | |
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| 399. | The Strange Science of Why We Dream | 52,743 | |
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| 400. | This is why astronauts look so WEIRD in zero g | 315,000 | |
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