| 301. | Super Battleship - (Sega Genesis/Mega Drive) | 159 | | Super Battleship
|
| 302. | Tecmo Super Baseball USA | 15 | | Tecmo Super Baseball
|
| 303. | Streets of Rage 2 - (Sega Genesis/Mega Drive) | 25 | | Streets of Rage 2
|
| 304. | Syndicate | 3 | |
|
| 305. | Super Baseball 2020 - (Sega Genesis/Mega Drive) | 22 | | Super Baseball 2020
|
| 306. | Streets of Rage 3 - (Sega Genesis/Mega Drive) | 29 | | Streets of Rage 3
|
| 307. | Street Racer - (Sega Genesis/Mega Drive) | 13 | |
|
| 308. | Super Volley Ball | 8 | |
|
| 309. | Strider - (Sega Genesis/Mega Drive) | 16 | | Streets of Rage
|
| 310. | Street Smart - (Sega Genesis/Mega Drive) | 33 | | Golden Axe
|
| 311. | Sword of Sodan | 5 | | Sword of Sodan
|
| 312. | Taz in Escape from Mars | 17 | | Taz in Escape from Mars
|
| 313. | Striker - (Sega Genesis/Mega Drive) | 52 | | Striker
|
| 314. | Sub-Terrania - (Sega Genesis/Mega Drive) | 10 | | Sub-Terrania
|
| 315. | Streets of Rage - (Sega Genesis/Mega Drive) | 14 | | Streets of Rage
|
| 316. | Super Street Fighter II-The New Challengers | 10 | | Street Fighter II
|
| 317. | Strider Returns-Journey from Darkness - (Sega Genesis/Mega Drive) | 40 | | Strider II
|
| 318. | Taz-Mania | 8 | | Taz-Mania
|
| 319. | Super Smash T.V. | 15 | | Smash TV
|
| 320. | Steel Talons - (Sega Genesis/Mega Drive) | 121 | | Steel Talons
|
| 321. | Sonic & Knuckles + Sonic the Hedgehog 2 - (Sega Genesis/Mega Drive) | 30 | | Sonic the Hedgehog 2
|
| 322. | Sonic the Hedgehog 3 - (Sega Genesis/Mega Drive) | 35 | | Sonic the Hedgehog 3
|
| 323. | Stormlord - (Sega Genesis/Mega Drive) | 65 | | Stormlord
|
| 324. | Starflight - (Sega Genesis/Mega Drive) | 56 | | Star Trek: The Next Generation – Future's Past
|
| 325. | Super Fantasy Zone - (Sega Genesis/Mega Drive) | 12 | | Super Fantasy Zone
|
| 326. | Sonic & Knuckles + Sonic the Hedgehog - (Sega Genesis/Mega Drive) | 29 | | Sonic & Knuckles
|
| 327. | Super High Impact - (Sega Genesis/Mega Drive) | 24 | |
|
| 328. | Sunset Riders - (Sega Genesis/Mega Drive) | 16 | | Sunset Riders
|
| 329. | Steel Empire - (Sega Genesis/Mega Drive) | 28 | | Steel Empire
|
| 330. | Super Off Road | 5 | | Super Off Road
|
| 331. | Super Hydlide | 9 | | Hydlide 3: The Space Memories
|
| 332. | Super Kick Off | 27 | | Super Kick Off
|
| 333. | Summer Challenge - (Sega Genesis/Mega Drive) | 41 | | The Games: Summer Challenge
|
| 334. | Street Fighter II'-Special Champion Edition - (Sega Genesis/Mega Drive) | 10 | | Street Fighter II
|
| 335. | Star Trek-The Next Generation-Echoes from the Past - (Sega Genesis/Mega Drive) | 24 | | Star Trek: The Next Generation – Future's Past
|
| 336. | Stargate - (Sega Genesis/Mega Drive) | 43 | | Star Trek: The Next Generation – Future's Past
|
| 337. | Spirou - (Sega Genesis/Mega Drive) | 108 | | Spirou
|
| 338. | Splatterhouse 3 - (Sega Genesis/Mega Drive) | 14 | | Splatterhouse 3
|
| 339. | Splatterhouse 2 - (Sega Genesis/Mega Drive) | 9 | | Splatterhouse 2
|
| 340. | Sports Talk Baseball - (Sega Genesis/Mega Drive) | 78 | | Sports Talk Baseball
|
| 341. | Spiritual Warfare - (Sega Genesis/Mega Drive) | 18 | | Spiritual Warfare
|
| 342. | Spider-Man and X-Men-Arcade's Revenge - (Sega Genesis/Mega Drive) | 22 | |
|
| 343. | Skitchin' - (Sega Genesis/Mega Drive) | 37 | | Skitchin'
|
| 344. | Slaughter Sport - (Sega Genesis/Mega Drive) | 29 | | Skitchin'
|
| 345. | Soldiers of Fortune - (Sega Genesis/Mega Drive) | 53 | |
|
| 346. | Skeleton Krew - (Sega Genesis/Mega Drive) | 11 | | Skeleton Krew
|
| 347. | Socket - (Sega Genesis/Mega Drive) | 42 | | Socket
|
| 348. | Sonic 3D Blast - (Sega Genesis/Mega Drive) | 33 | | Sonic 3D Blast
|
| 349. | Star Trek-Deep Space Nine-Crossroads of Time - (Sega Genesis/Mega Drive) | 38 | |
|
| 350. | Star Control - (Sega Genesis/Mega Drive) | 38 | | Star Control
|
| 351. | Spot Goes to Hollywood - (Sega Genesis/Mega Drive) | 21 | | Spot Goes To Hollywood
|
| 352. | Sonic & Knuckles - (Sega Genesis/Mega Drive) | 28 | |
|
| 353. | Sonic & Knuckles + Sonic the Hedgehog 3 - (Sega Genesis/Mega Drive) | 14 | | Sonic the Hedgehog 3
|
| 354. | Spider-Man-Acclaim - (Sega Genesis/Mega Drive) | 472 | | Spider-Man
|
| 355. | Sparkster - (Sega Genesis/Mega Drive) | 22 | | Sparkster: Rocket Knight Adventures 2
|
| 356. | Sonic Spinball - (Sega Genesis/Mega Drive) | 28 | | Sonic Spinball
|
| 357. | Shadow of the Beast II - (Sega Genesis/Mega Drive) | 21 | | Shadow of the Beast II
|
| 358. | Simpsons, The-Bart Vs. The Space Mutants - (Sega Genesis/Mega Drive) | 69 | | The Simpsons: Bart vs. the Space Mutants
|
| 359. | Shanghai II-Dragon's Eye - (Sega Genesis/Mega Drive) | 42 | |
|
| 360. | Spider-Man and Venom-Maximum Carnage - (Sega Genesis/Mega Drive) | 25 | | Spider-Man and Venom: Maximum Carnage
|
| 361. | Sonic the Hedgehog - (Sega Genesis/Mega Drive) | 46 | | Sonic the Hedgehog
|
| 362. | Speedball 2-Brutal Deluxe - (Sega Genesis/Mega Drive) | 16 | | Speedball 2: Brutal Deluxe
|
| 363. | Space Harrier II - (Sega Genesis/Mega Drive) | 23 | | Space Harrier II
|
| 364. | Spider-Man - (Sega Genesis/Mega Drive) | 19 | | Spider-Man
|
| 365. | Sonic Classics - (Sega Genesis/Mega Drive) | 307 | | Sonic Compilation
|
| 366. | Sonic the Hedgehog 2 - (Sega Genesis/Mega Drive) | 37 | | Sonic the Hedgehog 2
|
| 367. | Space Invaders '91 - (Sega Genesis/Mega Drive) | 20 | | Space Invaders
|
| 368. | Shadow of the Beast - (Sega Genesis/Mega Drive) | 15 | | Shadow of the Beast
|
| 369. | Shadow Dancer-The Secret of Shinobi - (Sega Genesis/Mega Drive) | 31 | | Shadow Dancer: The Secret of Shinobi
|
| 370. | Shaq-Fu - (Sega Genesis/Mega Drive) | 35 | |
|
| 371. | Spider-Man and Venom-Separation Anxiety - (Sega Genesis/Mega Drive) | 32 | | Venom/Spider-Man: Separation Anxiety
|
| 372. | Sorcerer's Kingdom - (Sega Genesis/Mega Drive) | 59 | | Sorcerer's Kingdom
|
| 373. | Shining Force II - (Sega Genesis/Mega Drive) | 19 | | Shining Force
|
| 374. | Saint Sword - (Sega Genesis/Mega Drive) | 33 | | Sonic the Hedgehog
|
| 375. | Sega Sports 1 - (Sega Genesis/Mega Drive) | 26 | |
|
| 376. | RoadBlasters - (Sega Genesis/Mega Drive) | 15 | | RoadBlasters
|
| 377. | Snake Rattle n Roll - (Sega Genesis/Mega Drive) | 38 | | Snake Rattle 'n' Roll
|
| 378. | Shining Force - (Sega Genesis/Mega Drive) | 10 | | Shining Force
|
| 379. | Simpsons, The-Bart's Nightmare - (Sega Genesis/Mega Drive) | 67 | | The Simpsons: Bart's Nightmare
|
| 380. | Smurfs, The - (Sega Genesis/Mega Drive) | 28 | | The Smurfs
|
| 381. | Sol-Deace - (Sega Genesis/Mega Drive) | 8 | | Sol-Feace
|
| 382. | Shove It! ...The Warehouse Game - (Sega Genesis/Mega Drive) | 131 | |
|
| 383. | Rolling Thunder 2 - (Sega Genesis/Mega Drive) | 14 | | Rolling Thunder 2
|
| 384. | Smurfs Travel the World, The - (Sega Genesis/Mega Drive) | 75 | | The Smurfs Travel the World
|
| 385. | Saturday Night Slammasters - (Sega Genesis/Mega Drive) | 13 | |
|
| 386. | Romance of the Three Kingdoms III-Dragon of Destiny - (Sega Genesis/Mega Drive) | 271 | | Romance of the Three Kingdoms III
|
| 387. | Shining in the Darkness - (Sega Genesis/Mega Drive) | 6 | | Shining in the Darkness
|
| 388. | RoboCop versus The Terminator - (Sega Genesis/Mega Drive) | 24 | | RoboCop Versus The Terminator
|
| 389. | Side Pocket - (Sega Genesis/Mega Drive) | 33 | | Side Pocket
|
| 390. | Shinobi III-Return of the Ninja Master - (Sega Genesis/Mega Drive) | 13 | | Shinobi III: Return of the Ninja Master
|
| 391. | Risky Woods - (Sega Genesis/Mega Drive) | 9 | | Risky Woods
|
| 392. | Samurai Shodown - (Sega Genesis/Mega Drive) | 31 | | Samurai Shodown
|
| 393. | Rolo to the Rescue - (Sega Genesis/Mega Drive) | 23 | | Rolo to the Rescue
|
| 394. | Second Samurai - (Sega Genesis/Mega Drive) | 64 | | Second Samurai
|
| 395. | Road Rash - (Sega Genesis/Mega Drive) | 17 | | Road Rash
|
| 396. | Rolling Thunder 3 - (Sega Genesis/Mega Drive) | 16 | | Rolling Thunder 3
|
| 397. | Sesame Street Counting Cafe - (Sega Genesis/Mega Drive) | 37 | | Sesame Street: Counting Cafe
|
| 398. | Sensible Soccer - (Sega Genesis/Mega Drive) | 6 | | Sensible Soccer
|
| 399. | Rampart - (Sega Genesis/Mega Drive) | 27 | | Rampart
|
| 400. | Ristar - (Sega Genesis/Mega Drive) | 21 | | Ristar
|
