| 401. | How Mushroom Time-Lapses Are Filmed | WIRED | 2,427 | |
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| 402. | Accent Expert Explains Why Different Accents Can Sound the Same | WIRED | 2,420 | Show |
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| 403. | Over 73 Million Sharks Killed Every Year for Fins | 2,410 | |
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| 404. | Astronomer Explains "Don't Look Up" Comet Scenes | WIRED | 2,400 | |
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| 405. | Marshmello Answers the Web's Most Searched Questions | WIRED | 2,400 | |
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| 406. | Todd Howard Breaks Down His Video Game Career | WIRED | 2,400 | |
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| 407. | Maya Expert Answers Maya Civilization Questions From Twitter | Tech Support | WIRED | 2,400 | | Civilization
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| 408. | Blackjack Expert Explains How Card Counting Works | WIRED | 2,387 | | Blackjack
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| 409. | Alicia Vikander Answers the Web's Most Searched Questions | WIRED | 2,387 | |
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| 410. | ER Doctor Answers Injury Questions From Twitter | Tech Support | WIRED | 2,377 | |
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| 411. | Biologist Answers More Biology Questions From Twitter | Tech Support | WIRED | 2,374 | Vlog |
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| 412. | How This Humanoid Robot Was Made | WIRED | 2,369 | |
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| 413. | The Fast & Furious Car Guy Answers Car Questions From Twitter | Tech Support | WIRED | 2,363 | Show |
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| 414. | Neil Gaiman Answers Mythology Questions From Twitter | Tech Support | WIRED | 2,346 | Vlog |
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| 415. | Jennifer Lawrence Explains How Good She Is at Archery | 2,344 | |
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| 416. | Doctor Explains What You Need to Know About Coronavirus | WIRED | 2,316 | |
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| 417. | Jeremy Clarkson, Richard Hammond & James May Show Us the Last Thing on Their Phones | WIRED | 2,315 | Show |
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| 418. | B.I Answers the Web's Most Searched Questions | WIRED | 2,306 | Show |
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| 419. | Neuroscientist Answers Illusion Questions From Twitter | Tech Support | WIRED | 2,300 | |
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| 420. | IVE Answer the Web's Most Searched Questions | WIRED | 2,300 | |
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| 421. | How PlayStation 5 Was Built (feat. Mark Cerny) | WIRED | 2,300 | | The Elder Scrolls V: Skyrim
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| 422. | Dream Answers The Web's Most Searched Questions | WIRED | 2,300 | |
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| 423. | San Diego Comic Con 2013: Giant Robot Storms-Geek Week-WIRED | 2,287 | |
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| 424. | Lily Collins & Nicholas Hoult Answer the Web's Most Searched Questions | WIRED | 2,272 | |
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| 425. | Kevin Hart & Tiffany Haddish Answer the Web's Most Searched Questions | WIRED | 2,269 | |
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| 426. | Survivorman Les Stroud Answers Survival Questions From Twitter | Tech Support | WIRED | 2,243 | Show | The Survivalists
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| 427. | Polo G Answers the Web's Most Searched Questions | WIRED | 2,240 | Show |
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| 428. | Will Ferrell & Amy Poehler Answer the Web's Most Searched Questions | WIRED | 2,236 | |
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| 429. | Every Trick a Pro GeoGuessr Player Uses to Win (ft. RAINBOLT) | WIRED | 2,226 | | GeoGuessr
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| 430. | Every Year’s Most Popular Toy Since 1969 Explained | Each and Every | WIRED | 2,223 | |
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| 431. | 13 Levels of Drumming: Easy to Complex | WIRED | 2,220 | |
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| 432. | Why It's Almost Impossible to Do a Quintuple Jump | WIRED | 2,209 | |
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| 433. | LaVar Ball Answers Basketball Questions From Twitter | Tech Support | WIRED | 2,205 | |
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| 434. | How Animals Are Rapidly Evolving Because of Climate Change | WIRED | 2,200 | |
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| 435. | Josh Hutcherson Answers the Web's Most Searched Questions | WIRED | 2,200 | |
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| 436. | Rare Nuclear Bomb Footage Reveals Their True Power | WIRED | 2,193 | |
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| 437. | Giant Star Wars LEGO Super Star Destroyer Shattered at 1000 fps | Battle Damage | 2,189 | Show |
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| 438. | Queer Eye Cast Answer the Web's Most Searched Questions | WIRED | 2,187 | |
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| 439. | Julia Roberts & Dermot Mulroney Answer the Web's Most Searched Questions | WIRED | 2,186 | | J.U.L.I.A.
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| 440. | Covid-19 Immunity Compared to 6 Other Diseases (Common Cold, HIV, SARS, and More) | Cause + Control | 2,184 | |
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| 441. | Cobra Kai Cast Test Martial Arts Gadgets | WIRED | 2,177 | |
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| 442. | Alex Honnold Answers Rock Climbing Questions From Twitter | Tech Support | WIRED | 2,176 | |
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| 443. | How Caffeine Addiction Changed History (ft. Michael Pollan) | WIRED | 2,176 | |
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| 444. | Former CIA Chief of Disguise Answers Spy Questions From Twitter | Tech Support | WIRED | 2,172 | |
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| 445. | Never Have I Ever Cast Answer the Web's Most Searched Questions | WIRED | 2,159 | Show |
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| 446. | Physicist Breaks Down Superhero Physics From Movies & TV | WIRED | 2,158 | Show |
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| 447. | Bill Gates Breaks Down 6 Moments From His Life | WIRED | 2,156 | |
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| 448. | Robotics Expert Breaks Down Robot Scenes From Film & TV | WIRED | 2,152 | Show |
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| 449. | Madison Beer Answers the Web's Most Searched Questions | WIRED | 2,142 | Show |
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| 450. | Former Air Force Fighter Pilot Breaks Down 12 Fighter Pilot Scenes From Film & TV | WIRED | 2,141 | Show | Fighter Pilot
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| 451. | Audio Experts Break Down The Most Common Tech Sounds | WIRED | 2,128 | |
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| 452. | Twitter Co-Founder Jack Dorsey Answers Twitter Questions From Twitter | Tech Support | WIRED | 2,122 | |
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| 453. | Statistician Answers Stats Questions From Twitter | Tech Support | WIRED | 2,106 | |
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| 454. | Olivia Rodrigo Answers The Web's Most Searched Questions | WIRED | 2,100 | |
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| 455. | Food Scientist Breaks Down Every Plant-Based Milk | WIRED | 2,085 | |
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| 456. | Watchmaker Breaks Down Swiss vs Japanese Made Watches | WIRED | 2,085 | |
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| 457. | How This Woman Rides 20,000 Miles a Year on Her Bike | WIRED | 2,084 | |
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| 458. | Gina Rodriguez Answers the Web's Most Searched Questions | WIRED | 2,079 | |
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| 459. | Forensics Expert Examines 25 More Crime Scene Investigations From Film & TV | WIRED | 2,079 | Show |
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| 460. | How Hevesh5 Builds Amazing Domino Chain Reactions | WIRED | 2,067 | |
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| 461. | Astronaut Answers Space Questions From Twitter | Tech Support | WIRED | 2,066 | |
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| 462. | Mark Hamill Answers the Web's Most Searched Questions | WIRED | 2,064 | |
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| 463. | Computer Scientist Explains Machine Learning in 5 Levels of Difficulty | WIRED | 2,052 | Show |
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| 464. | Nicolas Cage Explains WHY He Changed His Name | 2,047 | |
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| 465. | Bryce Dallas Howard Answers the Web's Most Searched Questions | WIRED | 2,037 | |
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| 466. | 2 Interpreters Test Their Interpreting Skills (Speed Challenge) | WIRED | 2,033 | |
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| 467. | Astronaut Chris Hadfield on 13 Moments That Changed His Life | WIRED | 2,021 | |
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| 468. | My Little Pony and the Brony Cult Following | Angry Nerd | 2,006 | |
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| 469. | <untitled video> | 2,000 | |
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| 470. | Bill Burr Answers The Web's Most Searched Questions | WIRED | 2,000 | |
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| 471. | Psychiatrist Answers Mental Health Questions From Twitter | Tech Support | WIRED | 2,000 | |
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| 472. | Taraji P. Henson & Tyler Perry Answer the Web's Most Searched Questions | WIRED | 1,999 | |
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| 473. | Is Priyanka Chopra Jonas Vegan? | 1,994 | |
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| 474. | Seth Rogen & Rose Byrne Answer The Web’s Most Searched Questions | WIRED | 1,963 | |
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| 475. | ‘Archer’ Cast Makes Trading Cards For Their Characters | WIRED | 1,962 | |
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| 476. | Mila Kunis & Justin Theroux Answer the Web's Most Searched Questions | WIRED | 1,933 | |
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| 477. | Keegan-Michael Key & Olivia Munn Answer the Web's Most Searched Questions | WIRED | 1,928 | |
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| 478. | Entomologist Breaks Down Bug Scenes From Movies & TV | WIRED | 1,926 | Vlog |
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| 479. | How This Woman Started Diving in DIY Submarines | Obsessed | WIRED | 1,920 | |
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| 480. | Scam Fighters Answer Scam Questions From Twitter (ft. Trilogy Media) | Tech Support | WIRED | 1,917 | Vlog | The Scam
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| 481. | Sleep Expert Debunks Common Sleep Myths | WIRED | 1,915 | Show |
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| 482. | Inside the LSD Museum That the DEA Somehow Hasn’t Nuked | WIRED | 1,913 | |
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| 483. | Kermit & Miss Piggy Answer the Web's Most Searched Questions | WIRED | 1,909 | Show |
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| 484. | Pro Driver Shows Off Tactical Driving Techniques | Tradecraft | WIRED | 1,907 | Show |
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| 485. | Billy Eichner & Cobie Smulders Answer the Web's Most Searched Questions | WIRED | 1,904 | |
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| 486. | Anderson Cooper Answers the Web's Most Searched Questions | WIRED | 1,902 | | ANDERSON
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| 487. | 'The Boys' Cast Answer The Web's Most Searched Questions | WIRED | 1,900 | |
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| 488. | Mechanical Engineer Answers Car Questions From Twitter | Tech Support | WIRED | 1,900 | |
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| 489. | Cat Expert Explains Why Some Cats Eat Human Corpses | WIRED | 1,898 | |
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| 490. | This Is Us Cast Answers the Web's Most Searched Questions | WIRED | 1,895 | |
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| 491. | New Xbox One: Kinect-Game|Life-WIRED Exclusive | 1,895 | | Kinect: Disneyland Adventures
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| 492. | Liam Neeson & Patrick Wilson Answer the Web's Most Searched Questions | WIRED | 1,883 | |
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| 493. | How a 5-Person Team Made an Oscar-Winning Movie's Effects | WIRED | 1,883 | |
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| 494. | Riding the New Hendo Hoverboard 2.0 | OOO with Brent Rose | 1,867 | |
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| 495. | Meet the 89-Year Old Who Built a Train in His Backyard | WIRED | 1,864 | |
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| 496. | Mayim Bialik Answers Neuroscience Questions From Twitter | Tech Support | WIRED | 1,864 | Show |
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| 497. | Smosh Answer The Web's Most Searched Questions | WIRED | 1,862 | |
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| 498. | How to Start a Fire in a Survival Situation | Basic Instincts | WIRED | 1,860 | Guide |
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| 499. | On My Block Cast Answer the Web's Most Searched Questions | WIRED | 1,860 | Show |
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| 500. | Hyperloop's Next Successful Test Launch Brings It Closer Than Ever | WIRED | 1,851 | |
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