| 301. | Jeff Goldblum Answers the Web's Most Searched Questions | WIRED | 3,366 | |
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| 302. | Nigel Ng & Uncle Roger Answer the Web's Most Searched Questions | WIRED | 3,360 | |
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| 303. | Riot Games' Greg Street Answers League of Legends Questions from Twitter | Tech Support | WIRED | 3,345 | | League of Legends
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| 304. | Architecture Professor Explains Why Malls Are Dying | WIRED | 3,292 | |
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| 305. | John Cena & Keegan-Michael Key Explore Their Impact on the Internet | WIRED | 3,272 | Show |
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| 306. | Fun With Powdered Alcohol: You Can Stop Being Scared Now | 3,251 | |
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| 307. | U.S. - China Relations, Explained | WIRED | 3,225 | |
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| 308. | Markiplier Explores His Impact on the Internet | Data of Me | WIRED | 3,225 | Show |
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| 309. | Inside the Quest to Make Lab Grown Meat | WIRED | 3,197 | |
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| 310. | Botanist Answers Plant Questions From Twitter | Tech Support | WIRED | 3,191 | |
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| 311. | Keke Palmer Answers the Web's Most Searched Questions | WIRED | 3,190 | |
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| 312. | How This Guy Stacks Playing Cards Impossibly High | Obsessed | WIRED | 3,188 | |
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| 313. | 26 Levels of Yo-Yo Tricks: Easy to Complex | WIRED | 3,185 | Show |
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| 314. | Cannabis Scientist Answers Questions From Twitter | Tech Support | WIRED | 3,174 | |
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| 315. | Climate Scientist Answers Earth Questions From Twitter | Tech Support | WIRED | 3,170 | |
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| 316. | Owen Wilson Answers The Web’s Most Searched Questions | WIRED | 3,166 | |
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| 317. | James McAvoy & Sarah Paulson Answer the Web's Most Searched Questions | WIRED | 3,153 | |
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| 318. | Chemist Breaks Down 22 Chemistry Scenes From Movies & TV | WIRED | 3,126 | |
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| 319. | Every Race In Middle-Earth Explained | WIRED | 3,121 | Show |
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| 320. | NASA Astronaut Breaks Down Space Scenes From Film & TV | WIRED | 3,111 | |
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| 321. | Every Mortal Kombat 11 Ultimate Friendship Explained By Ed Boon | WIRED | 3,111 | | Mortal Kombat 11
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| 322. | Sophie Turner & Jessica Chastain Answer the Web's Most Searched Questions | WIRED | 3,105 | |
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| 323. | How Scientists Are Preparing Earth for an Incoming Asteroid | WIRED | 3,067 | |
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| 324. | Lilly Singh Answers the Web's Most Searched Questions | WIRED | 3,066 | |
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| 325. | Outer Banks Cast Answer the Web's Most Searched Questions | WIRED | 3,061 | Show |
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| 326. | How This Guy Became a World Champion Boomerang Thrower | WIRED | 3,049 | Vlog |
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| 327. | How to Fold Five Incredible Paper Airplanes | WIRED | 3,030 | Tutorial |
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| 328. | Surgeon Breaks Down 22 Medical Scenes From Film & TV | WIRED | 2,979 | Show |
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| 329. | Retired Navy SEAL Explains How to Prepare for Dangerous Situations | Tradecraft | WIRED | 2,972 | Guide |
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| 330. | How Animators Created the Spider-Verse | WIRED | 2,965 | |
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| 331. | Sleep Expert Answers Questions From Twitter 💤 | Tech Support | WIRED | 2,937 | |
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| 332. | Mathematician Answers Math Questions From Twitter | Tech Support | WIRED | 2,896 | |
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| 333. | Chris Hemsworth Answers the Web's Most Searched Questions | WIRED | 2,882 | |
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| 334. | Can Prosthetics Outperform Real Limbs? | Cyborg Nation | 2,878 | |
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| 335. | Charlie Day Answers the Web's Most Searched Questions | WIRED | 2,868 | |
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| 336. | Gal Gadot, Alia Bhatt & Jamie Dornan Answer The Web's Most Searched Questions | WIRED | 2,845 | |
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| 337. | Theoretical Physicist Breaks Down the Marvel Multiverse (ft. Michio Kaku) | WIRED | 2,839 | |
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| 338. | Former FBI Agent Breaks Down Interrogation Techniques | WIRED | 2,821 | |
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| 339. | James Hoffmann Answers Coffee Questions From Twitter | Tech Support | WIRED | 2,815 | |
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| 340. | Google Search Team Answers the Web's Most Searched Questions | WIRED | 2,813 | |
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| 341. | MONSTA X Answer the Web's Most Searched Questions | WIRED | 2,805 | Show |
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| 342. | How This Woman Blows Record-Breaking Bubbles | WIRED | 2,801 | Show |
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| 343. | Taste Expert Answers Flavor Questions From Twitter | Tech Support | WIRED | 2,800 | |
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| 344. | 'Avatar: The Last Airbender' Cast Answer Avatar's Most Googled Questions | WIRED | 2,800 | | Avatar: The Last Airbender
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| 345. | Surgeon Explains How to Apply Stitches | WIRED | 2,793 | Tutorial |
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| 346. | Scientist Explains Sleep in 5 Levels of Difficulty | WIRED | 2,792 | Show |
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| 347. | Waste Expert Answers Garbage Questions From Twitter | Tech Support | WIRED | 2,777 | |
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| 348. | Salma Hayek & Eugenio Derbez Answer the Web's Most Searched Questions | WIRED | 2,774 | Show |
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| 349. | Meet the HyperAdapt, Nike's Awesome New Power-Lacing Sneaker | WIRED | 2,771 | |
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| 350. | Colin Farrell & Danny DeVito Answer the Web's Most Searched Questions | WIRED | 2,769 | |
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| 351. | Every C-3PO Costume Explained By Anthony Daniels | WIRED | 2,765 | Show |
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| 352. | Bon Appétit's Brad & Claire Answer Cooking Questions From Twitter | Tech Support | WIRED | 2,757 | |
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| 353. | LegalEagle's Devin Stone Answers Law Questions From Twitter | Tech Support | WIRED | 2,757 | |
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| 354. | Nick Jonas Answers the Web's Most Searched Questions | WIRED | 2,757 | |
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| 355. | Why It’s Almost Impossible to Score a Corner Kick Goal in Soccer / Football | WIRED | 2,750 | |
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| 356. | Aubrey Plaza & Craig Robinson Answer the Web's Most Searched Questions | WIRED | 2,744 | |
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| 357. | Stanford Computer Scientist Answers Coding Questions From Twitter | Tech Support | WIRED | 2,741 | |
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| 358. | 11 Levels of Drawing Yourself: Easy to Complex | WIRED | 2,739 | Show |
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| 359. | Liza Koshy, Markiplier, Rhett & Link, and Hannah Hart Answer YouTube Creator Questions From Twitter | 2,730 | Show |
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| 360. | John Cena Guesses Famous Robots | WIRED | 2,721 | |
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| 361. | Scientist Explains How Some People Need Only 4 Hours of Sleep | WIRED | 2,709 | |
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| 362. | 'The Boys' Cast Answer 'The Boys' Most Googled Questions | WIRED | 2,700 | |
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| 363. | Danny DeVito Answers the Web's Most Searched Questions | WIRED | 2,690 | |
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| 364. | Priyanka Chopra, Rebel Wilson & Adam Devine Answer the Web's Most Searched Questions | WIRED | 2,684 | |
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| 365. | Mycologist Answers Mushroom Questions From Twitter | Tech Support | WIRED | 2,678 | Vlog |
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| 366. | Ricky Gervais Answers the Web's Most Searched Questions | WIRED | 2,677 | |
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| 367. | Sushi Chef Answers Sushi Questions From Twitter | Tech Support | WIRED | 2,676 | |
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| 368. | Jennifer Lopez & Leah Remini Answer the Web's Most Searched Questions | WIRED | 2,668 | |
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| 369. | Sofía Vergara & Simon Cowell Answer the Web's Most Searched Questions | WIRED | 2,647 | |
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| 370. | Joe Manganiello Answers Dungeons & Dragons Questions From Twitter | Tech Support | WIRED | 2,639 | Tutorial | Dungeons
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| 371. | Virtual Reality Engineer Explains One Concept in 5 Levels of Difficulty | WIRED | 2,638 | Show |
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| 372. | Why It's Almost Impossible to Do a Quintuple Cork in Tricking | WIRED | 2,633 | |
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| 373. | Inside Keanu Reeves' Custom Motorcycle Shop | WIRED | 2,633 | |
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| 374. | Ellie Kemper Answers the Web's Most Searched Questions | WIRED | 2,626 | |
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| 375. | How Black Panther's Visual Effects Were Made | WIRED | 2,626 | | Black Panther
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| 376. | Elijah Wood Explores His Impact on the Internet | Data of Me | WIRED | 2,624 | Show |
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| 377. | Ninja Answers Fortnite Questions From Twitter | Tech Support | WIRED | 2,614 | | Fortnite
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| 378. | Daniel Craig & Lashana Lynch Answer the Web's Most Searched Questions | 2,607 | | GoldenEye 007
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| 379. | Survivalist Answers Survival Questions From Twitter | Tech Support | WIRED | 2,600 | |
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| 380. | Dominic Monaghan & Billy Boyd Answer the Web's Most Searched Questions | WIRED | 2,600 | |
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| 381. | Primatologist Answers Ape Questions From Twitter | Tech Support | WIRED | 2,600 | |
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| 382. | Paleoanthropologist Answers Caveman Questions From Twitter | Tech Support | WIRED | 2,600 | |
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| 383. | Tony Hawk Answers the Web's Most Searched Questions | WIRED | 2,593 | |
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| 384. | 'Critical Role' Cast Answers The Web's Most Searched Questions | WIRED | 2,587 | |
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| 385. | What Could Happen in a World That's 4 Degrees Warmer | WIRED Brand Lab | 2,585 | |
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| 386. | How This Woman Creates God of War’s Sound Effects | Obsessed | WIRED | 2,581 | | God of War Ragnarök
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| 387. | Wolfgang Puck Answers Restaurant Questions From Twitter | Tech Support | WIRED | 2,566 | Show |
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| 388. | Anne Hathaway & Jason Sudeikis Answer the Web's Most Searched Questions | WIRED | 2,566 | |
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| 389. | Rich Brian and NIKI Answer the Web's Most Searched Questions | WIRED | 2,536 | Show |
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| 390. | Aaron Paul & Emily Ratajkowski Answer the Web's Most Searched Questions | WIRED | 2,532 | |
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| 391. | Every Starfighter in Star Wars Explained By Lucasfilm | WIRED | 2,532 | Show | Star Wars: Starfighter
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| 392. | Every Dog Breed Explained (Part 2) | WIRED | 2,526 | |
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| 393. | Mark Cuban Answers Business Questions From Twitter | Tech Support | WIRED | 2,520 | |
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| 394. | Marine Biologist Answers Fish Questions From Twitter | Tech Support | WIRED | 2,500 | |
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| 395. | Veterinarian Answers Pet Questions From Twitter | Tech Support | WIRED | 2,487 | |
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| 396. | Kiernan Shipka & Isabela Merced Answer the Web's Most Searched Questions | WIRED | 2,486 | |
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| 397. | Why It's Almost Impossible to Run a Two-Hour Marathon | WIRED | 2,468 | |
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| 398. | Every 'Useless' Body Part Explained From Head to Toe | WIRED | 2,463 | |
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| 399. | Why It's Almost Impossible to Shot Put 24 Meters | WIRED | 2,458 | |
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| 400. | Why Holding Your Breath For 24 Minutes Is Almost Impossible | WIRED | 2,444 | |
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