Top 100 The Binding of Isaac Videos With The Most Comments by Daring The Shiba InuTop 100 » 200 » 300 » 400 » 500Video TitleCommentsCategoryGame1.The Binding Of Isaac |Wrath Of The Lamb: Eternal Edition| EVERYTHING'S DIFFERENT!5The Binding of Isaac 2.The Binding Of Isaac |Eve| THE EASIEST BOSS SINCE MONSTRO!5The Binding of Isaac 3.The Binding Of Isaac |Cain| BOMBS AND KEYS GALORE!4The Binding of Isaac 4.The Binding Of Isaac |Magdalene| PRETTY MUCH ISAAC IN A WIG3The Binding of Isaac 5.The Binding Of Isaac | I WONT DIE FROM BOUNCING ONSIES!2The Binding of Isaac 6.The Binding Of Isaac (Hard Mode) | THE DREADED 3rd LEVEL0The Binding of Isaac 7.The Binding Of Isaac (Hard Mode) | The Cut0The Binding of Isaac 8.The Binding Of Isaac | THE WHORE OF BABYLON VS THE FALLEN0The Binding of Isaac 9.WELP, I'M LOST | Annventure of a Lifetime #130The Binding of Isaac 10.Playing Some OG Isaac0The Binding of Isaac 11.The Binding Of Isaac Meets Never Ending Nightmares (Withering Rooms)0The Binding of Isaac 12.The Binding Of Isaac | CURSE OF THE LABYRINTH0The Binding of Isaac 13.Neon Abyss | Binding Of Isaac: Hotline Miami Style0The Binding of Isaac 14.The Binding Of Isaac | Hard Mode0The Binding of Isaac Top 100 » 200 » 300 » 400 » 500