| 2024-02-26 |  Ninja Kuma | 39,700 | GET ZI FLAMMENWERFER | Let's Play ALIEN ISOLATION Blind Playthrough [4] ALIEN ISOLATION Reaction | 2:11:22 |
| 2023-12-01 | juzcook Longplays | 4,090 | Alien Isolation // Full Playthrough (Longplay) (Part #4 FINALE) | 4:27:21 |
| 2023-10-30 | MrDonut | 509 | Alien Isolation First Playthrough | 27:35 |
| 2023-08-22 | ThisIsSyd | 129 | Alien isolation 2nd Playthrough (Ending) | 3:22:17 |
| 2023-06-04 | Numaticin | 167 | Dropping in for a Visit - Alien Isolation Let's Play - Highlights | 1:00 |
| 2023-03-05 | Haydo07 | 28 | Things are Getting Interesting! | Alien Isolation [Let's Play EP 2] | 24:56 |
| 2023-01-26 | Cosmic Garbage | 31 | Best of | Alien Isolation | 2:08:58 |
| 2022-01-24 | MaddieWM | 75 | LIAM PLAYS ALIEN ISOLATION PART 2 | Maddiewm | 1:50:54 |
| 2021-10-23 | The Scarlet Seeker | 35,100 | 🔴 Alien: Isolation | Overview & Gameplay (2021 LIVE FULL PLAYTHROUGH) | 3:30:27 |
| 2021-10-21 | WatchDanGame | 802 | ALIEN ISOLATION Playthrough | Part 2 | PC Gameplay with Commentary | 6:15:14 |
| 2021-09-08 | Mapocolops | 86,500 | Ellen Ripley, The Last Survivor - Alien: Isolation | Blind Playthrough [Part 17] | 33:13 |
| 2021-07-23 | BoulderBum | 1,230 | LIVE - Alien: Isolation with BoulderBum & Doggo Cam Part 2 [LIVE PC GAMEPLAY] | 5:47:02 |
| 2021-06-08 | Stooge Potato | 167 | Alien Isolation "First Playthrough" - Twitch Highlights!! Part 1 | 11:04 |
| 2021-04-08 | Sebbywebz | 96,400 | Watch Me Rage On ALIEN ISOLATION | Best Reactions | Scare Compilation, First Playthrough | 5:01 |
| 2020-07-29 | GirlFromAus | 31,800 | Alien Isolation Playthrough Part 11 - An Insane Ending | 1:18:39 |
| 2019-10-07 | Astraldragon Gaming | 115 | Eurogamer | Alien Isolation | Super yelp cut | 1:28:35 |
| 2018-03-10 | The Greedy Wolf | 176 | Aussie Plays Alien: Isolation Finale - "Im all Alone" | 2:08:35 |
| 2017-10-13 | Kinda Dorky Fun Times | 1,570 | IT'S FOLLOWING ME! | Antiseptic | 10:51 |
| 2017-09-18 | Neversurrendr | 27,100 | ALIEN: ISOLATION!!👽| Live Playthrough - ENDING! | 1080P | Interactive Streamer | 5:28:24 |
| 2017-09-16 | Kamilian | 364 | Kami Plays Alien Isolation LIVE Trailer | 1:11 |
| 2017-06-23 | Rajin Fox | 57 | Lets Finish This | Lets Play Alien Isolation Final Part | 38:02 |
| 2016-10-07 | BlueOx1d3 | 8 | Let's play Alien Isolation - Part 5 | A HORRIFIC DEATH | 46:49 |
| 2016-06-30 | JezzaGamingHD | 262 | Markiplier Plays Alien Isolation Part #5 | 53:18 |
| 2016-03-26 | Unbealievable | 3,060 | Livestream Archive \\ Let's Play Alien: Isolation w/ My Girlfriend Janome \\ STOP BREATHING #3 | 1:32:16 |
| 2016-03-14 | Intoxigamer | 8,430 | Alien: Isolation Playthrough - Part 15 | IF IT MOVES... SHOOT IT! | 24:37 |
| 2015-11-01 | ClassicalChip | 231 | Ben Plays Alien: Isolation #2 (Halloween Special) | 26:29 |
| 2015-05-21 | goukigod | 25,700 | Alien Isolation: Crew Expendable Let's Play [PS4] | 7:33 |
| 2015-01-22 | BrokenOpus | 1,180 | Alien Isolation - Glitches and Funny Moments (PS4 Gameplay Montage) | 3:48 |
| 2015-01-08 | The RAMPAGE | 623 | Alien: Isolation Hard PC Playthrough w/ Facecam - Part 28 - Final - YAY | 23:55 |
| 2014-11-19 | No Time To Grind | 29,600 | Alien Isolation Playthrough: Part 22 - DEATH EVERYWHERE | 14:15 |
| 2014-10-31 | Menaero | 5,780 | Alien: Isolation | SWEAT AND FEAR! | 37:46 |
| 2014-10-28 | tr1ppa | 16,400 | Alien Isolation Gameplay [Last Survivor DLC Complete Playthrough] [PC HD] | 19:07 |
| 2014-10-17 | go | 3,840 | Let's Play ALIEN: ISOLATION #010 - Nur keine Panik! [NoComment/HD/GERMAN] | 30:11 |
| 2014-10-09 | The AGExp Show | 3,850 | Alien Isolation Lets Play Pt.1 | 1:22:27 |
