| 1. |  Parka Blogs | 21,417 | The Art of Alien: Isolation (book flip) | 3:03 |
| 2. | Metaverse ∞ | 6,937 | DEADLIEST XENOMORPH ambush at the WORST moment #shorts | 0:22 |
| 3. | Rookielahs2 | 5,438 | Roblox Alien: Isolation *UPDATE*- AVOID SYNTHETIC PERSON WITH RED EYES | 45:36 |
| 4. | Iora Ch. | 5,340 | 【Alien: Isolation】Are We Nearing The End?【VTUBER】 | 5:12:47 |
| 5. | Rana Ianna Ch. | 3,607 | I love this game【PUMMEL PARTY COLLAB】 | 2:41:10 |
| 6. | GA Myanmar Entertainment | 3,583 | Mobile Games for Halloween | 0:00 |
| 7. | Xbox Asia | 2,722 | Alien Isolation - Official Announcement Gameplay Trailer - Transmission | 1:19 |
| 8. | ValkyTheMeow | 1,092 | Blind play through Alien Isolation Part 4 | 0:00 |
| 9. | Pizzy | 1,042 | Alien Isolation ENDING/FINAL MISSION - Gameplay Walkthrough Part 31 - Tomorrow,Together (PC) | 18:43 |
| 10. | Alden Ryouken | SNOWDROP LIVE | 859 | 【ALIEN: ISOLATION】Hari Hari Dikejar Alien【SNOWDROP ID 2nd GEN】 | 2:14:55 |
| 11. | Proper D | 847 | What else are you supposed to do in an elevator? | Arktika.1 VR Funny Fail | 0:23 |
| 12. | Iva Hellock | 748 | Androids NO | 0:41 |
| 13. | AyinMaiden | 718 | My Alien Isolation Twitch Clips Compilation | 7:53 |
| 14. | thecomicman | 493 | GET ON THE TORRENS! - Alien: Isolation Episode 8 | 0:00 |
| 15. | Neuroisdelicious | 429 | ALIEN ISOLATION EP3 - NIGHTMARE (Hardest Difficulty) | 55:33 |
| 16. | Ninomiya Sho | SNOWDROP LIVE | 298 | [SeiShon't Donothon] Makima WangyWangy~♥ & Kitsune in Space!! Day #9 Donothon【SNOWDROP ID 2nd GEN 】 | 4:26:24 |
| 17. | R3vobrenYT | 267 | Alien isolation - Gameplay Walkthrough - Part 13 - THE END FINALLY!! | 56:01 |
| 18. | Casual Gamers Online | 258 | Alien Isolation - Livestream EP 01 | 2:17:57 |
| 19. | Paiku | 181 | abigfatpig PLAYS ALIEN: ISOLATION | Full Gameplay - Part 11 - AMANDA SURVIVES? BUT IS SHE PREGGERS? | 2:37:54 |
| 20. | Mansor | 109 | Minecraft | Alien Isolation #4 FINAL! | Horror Map | 10:10 |
| 21. | Chiaki Nadeshiko | 95 | we here again. | ALIEN ISOLATION | 1:29:03 |
| 22. | FoxTwo | 82 | Alien Isolation - Prologue | 21:13 |
| 23. | MaldinYong | 75 | alien isolation stream or something | 2:21:34 |
| 24. | Yat in the Hat | 68 | I only have the hoyaa | Alien Isolation #twitch #streamer #alienisolation #gaming #horror | 0:10 |
| 25. | Pithy Gaming Clips | 64 | Alien: Isolation (Xbox Series X) Livestream Part 6 ~ END | 5:24:48 |
| 26. | Felix Alexis | 56 | Aliens Isolation is just silly sometimes. | 0:00 |
| 27. | Tanna Time | 42 | Alien: Isolation | Beginning | Terror Tuesday | Tanna Time | 1:06:37 |
| 28. | Krekalie | 40 | Alien : Isolation - Deeper into Medical we go! | 0:00 |
| 29. | អាយុវែង | 28 | EP10 Isolation - Alien #ActionGame | 20:39 |
| 30. | JamieSPAM | 27 | UFO SIGHTING IN FARMHOUSE - They Are Here Alien Abduction Horror | 11:48 |
| 31. | KyuzoPlays | 22 | Kyuzoplays Alien Isolation Part 5 | 20:59 |
| 32. | SYOU Official | 13 | YouTube Gaming | S.S TV Live Stream - Alien: Isolation -Nightmare- | 6:56:23 |
| 33. | Hydrecide | 10 | indie horror on a Monday – We Went Back | 52:48 |
| 34. | HooliganZ Gaming | 9 | HooliganZ Plays A-Z [Alien Isolation] Gameplay | 1:00:35 |
| 35. | AwesDes VODs | 6 | 【Alien: Isolation, Hearts of Iron IV】horror game once more | Twitch VOD | 1:14:56 |
| 36. | Seig Verchill | 5 | Help! Save me! Aliens trying to find out if i'm goated with the sauce. | 3:21:43 |
| 37. | gyinnyin | 5 | Observation: FINAL | 2:15:11 |
| 38. | Berrylimbeili | 3 | I can't resist #stealth #alienisolation #shorts #light | 0:32 |
