| 1. |  G.O.T Games | 138,034 | First Time Reacting to ONE PIECE FILM RED | Ado "New Genesis" | Non Anime Fan! | 12:57 |
| 2. | Lady Decade | 92,507 | The LOST Atari Genesis - Gaming History Secrets | 14:49 |
| 3. | Deadpan Flook | 14,297 | MTV's Beavis & Butthead ( Megadrive/Genesis, Game Gear, SNES) Preview Trailer | 0:33 |
| 4. | G.O.T Extra | 11,229 | AQUARION *OPENING* | AKINO "Genesis of Aquarion" | REACTION!! | 0:00 |
| 5. | EXTREME YouTube Gaming Channel | 10,427 | James Pond II: Codename RoboCod - Complete Soundtrack OST (Sega Mega Drive / Genesis) | 13:19 |
| 6. | AntHazuki | 10,152 | Sega Mega Drive & Genesis Classics | Analysis: All 50 Games, Features, Trophies & Challenges! | 8:14 |
| 7. | Matteusbeus - Retro Sega Dev | 6,283 | Akira FMV on Sega Mega Drive & Genesis using SGDK? | 1:42 |
| 8. | ACGamer | 5,885 | Goddess of Genesis S: Top 5 Units To reroll For | 13:29 |
| 9. | RetroBreak | 3,372 | Genesis Homebrew Review - A New Game Boy Shoot Em Up! | 8:49 |
| 10. | Kevin Muldoon | 3,337 | Sega Mega Drive Mini - Unboxing, Gameplay & Review (Sega Genesis Mini) | 50:48 |
| 11. | MikeyTheMachineGaming | 2,608 | Hook (Sega Genesis) - Longplay (Full Game) (Sega Genesis/MegaDrive) | 41:25 |
| 12. | 80sretrogamer | 2,288 | Bonkers Sega Mega Drive Genesis Review | 9:18 |
| 13. | All Things Wrestling | 2,021 | Sega Mega Drive/Genesis Mk1 l Random Stuff I Brought Episode 3 #shorts #megadrive #genesis #sega | 0:59 |
| 14. | TheDriver | 1,806 | Souten no Ken Re:Genesis (蒼天の拳 RE:GENESIS) Episode 1 Live Reaction/First Impressions | 32:18 |
| 15. | Retro Master | 1,681 | Sonic Neo Genesis Knuckles & Sonic playthrough | 52:16 |
| 16. | tribalkai | 1,204 | Shorikai Genesis Engine Vehicle Deck | MTG Commander Gameplay | tribalkai | 34:51 |
| 17. | Right Sprite Retro Gaming UK | 1,185 | Life on Mars Genesis New Sega Megadrive / Genesis Games 2023 | 10:30 |
| 18. | Gaming Archive | 928 | 3 Ways To Connect a Sega Mega Drive To a Modern TV - Setup The MegaDrive TV Connection Sega Genesis | 11:41 |
| 19. | AlacrityBlue♪ | 925 | The Lion King - Sega Genesis (Complete Full OST) | 41:17 |
| 20. | SkyTrap Al ASMR | 871 | ASMR Whisper Genesis/Solo Genesis Vinyl and CD collections. | 1:02:11 |
| 21. | VGCW Network | 754 | WVGCW GENESIS S5E16: Final: 10: Match 2/3 Falls Genesis V Final: Djeeta Vs. Aerith Gainsborough | 21:42 |
| 22. | SilverStormShadow | 679 | The Genesis VGT is AMAZING at Sardegna | Genesis VGT 800PP Build in GT7 | 2:12 |
| 23. | Ashley Eleanor | 636 | Genesis GV60 - The FIRST Genesis all electric SUV comes to the UK | 1:00 |
| 24. | Ocean Core | 451 | Unraveling the Champion: Who Won The Genesis Scotland Open? | 4:11 |
| 25. | Freddtor Official Gaming | 421 | Genesis Could Be Better? What's a MOBA? | 9:54 |
| 26. | thesegaguru | 291 | HOMEBREW PREVIEW - ARKAGIS - SEGA MEGADRIVE/GENESIS | 7:53 |
| 27. | PotatoProWrestling | 269 | Sega Genesis Flashback Console Trailer Reaction | 3:43 |
| 28. | Craigy Boy Gaming | 228 | Genesis Does! Do You Remember This SEGA Genesis TV Commercial? | 0:30 |
| 29. | Excolo | 176 | Genesis vs Aeternum 24/09/10 Second Half | 7:45 |
| 30. | Yester Quest | 151 | The Mega Drive / Genesis Mysteries #4 | put your Sega games knowledge to the test! | 5:27 |
| 31. | TheElder Gamer | 148 | #Sega #Megadrive #AtGames will it play #Genesis and #Japanese #RetroGames? Cart Testing. | 0:00 |
| 32. | Betty Horde Clinic | 138 | Mega Drive : Genesis 2 mini | 52:01 |
| 33. | Latest TV | 130 | Steve Hackett & The Genesis of Genesis | 16:01 |
| 34. | Video Game Therapy | 115 | 5 Sega Genesis/Mega Drive facts. | 13:03 |
| 35. | XPN Network | 108 | Peter Kelamis - Digi-Con 5: Genesis Message | 0:26 |
| 36. | NapazTrix | 64 | Genesis Radium 600 Microphone - Review | 4:15 |
| 37. | Mega Drive Sound | 64 | Genesis - Another Record (Mega Drive Cover) | 4:16 |
| 38. | Kev Gaming XP | 59 | Sega Genesis Montage | 0:36 |
| 39. | Spirit Wolf Gaming | 25 | Maou Renjishi (Sega Genesis) | 0:00 |
| 40. | Idah09H | 25 | specifc speedrunning - the genesis project, parricide. 32.58 | 1:08 |
| 41. | Jason Hardy | 20 | ZACK VS GENESIS #shorts #walkthrough #playthrough #genesis #zack #letsplay #gaming #game #twitch | 0:11 |
| 42. | shirlierox | 9 | I PLAYED THIS GAME IN THE DARK BY MISTAKE - M.E.R.C. Genesis first look | 17:12 |
| 43. | SpongyChicken | 7 | I, Dracula Genesis Announcement Trailer (PC) MAY 2020 | 1:41 |
