| 1. |  YuB | 479,022 | CAN YOU SPOT THE DIFFERENCE? (99% CANNOT) Mario Paint Gameplay | 10:56 |
| 2. | ProJared Plays! | 99,249 | Drawing YouTubers: PushingUpRoses! │ Mario Paint #3 │ ProJared Plays! | 25:02 |
| 3. | NintendoComplete | 42,893 | Mario Paint (SNES) Playthrough - NintendoComplete | 37:06 |
| 4. | Cinemassacre Clips | 40,371 | Mario Paint Request Stream - Cinemassacre Plays | 2:14:45 |
| 5. | Lancer | 11,153 | Let's Play Mario Paint - Part 02: More Messing Around | 10:41 |
| 6. |  LETSPLAYmarkus | 11,065 | Let's Test # 246 🎨 MARIO PAINT | 29:52 |
| 7. | IGN | 8,713 | Mario Paint - IGN Plays | 8:34 |
| 8. | Famicom Dojo | 5,794 | Sara Plays Mario Paint (Super Famicom) | 7:15 |
| 9. | RageSelect | 4,534 | Sparkle Fandango Episode 10 - Let's Play Mario Paint | 53:36 |
| 10. | Marc Lovallo | 3,158 | Mario One-Offs | Summer of Mario 2022 | 36:17 |
| 11. | TopKirby8305 | 1,992 | TK's Lets Play: Mario Paint (SNES) [HQ] | 13:51 |
| 12. | 8ByteBrian | 1,920 | Let's Play Mario Paint | 8:14 |
| 13. | buckyboy2009 | 1,788 | Mario Paint Composer | Original Composition #6 | Willpower | 1:25 |
| 14. | ZeoLightning | 1,609 | Zeo's LP - Luigi's Mansion (Part 9): Mario Paint | 12:49 |
| 15. | frocto1 | 644 | Let's Play Mario Paint | 3:29 |
| 16. | VvvvvaVvvvvvr | 588 | Let's Play Mario Paint - Part 1 | 4:34 |
| 17. |  Megatron collection | 478 | Mario Paint Selection - vinyl LP (Bootleg) | 20:34 |
| 18. | ZetaPlays | 414 | Fun-N-Games (GENESIS) - Totally Not Mario Paint | 33:05 |
| 19. | EZLO21 | 376 | Mario Paint Better Playthrough | 24:10 |
| 20. | Antistar | 366 | MARIOTHON #12 – Let's play MARIO PAINT et MARIO IS MISSING! (SUPER NINTENDO) | 4:17:45 |
| 21. | ProHipStar | 277 | Let's Play Mario Paint | ''The Good Music, The Scary Music'' | 28:58 |
| 22. | IGN Plays | 201 | Mario Paint - IGN Plays | 8:34 |
| 23. |  Tequila Gaming | 191 | Dibujando a ALPHA en MARIO PAINT - Tequila Plays | 40:28 |
| 24. | LagsMBH | 190 | Let's Play Mario Paint Part 1 | 2:31 |
| 25. | BroedgeMan | 142 | Let's Play Weegee's Hidden Mansion Folge VII - Mario Paint | 19:07 |
| 26. | LPMaster6 | 111 | Let's Play Mario Paint: Winner Built-In Version | 21:00 |
| 27. | The Kingdom of Retro Gaming | 79 | This system plays BOTH NES and SNES games! | 19:03 |
| 28. | Boy Meets Nintendo | 69 | PENNY PLAYS - Mario Paint (SNES) | 14:46 |
| 29. | MabiVsGames | 69 | MARIO PAINT DIRT CHEAP?! | The Collection - Cataloging My SNES Games #3 | 16:04 |
| 30. | Sheena Plays | 65 | Sheena Plays Around With Mario Paint | 41:37 |
| 31. | Channel92 | 62 | Lets Play - Mario Paint [SPEZIAL LP] Ein Zeichner und Animations Game | 16:49 |
| 32. | Flynn Jeux | 50 | Tea and Jeux Create a 3DMM Shitpost Cringe for A Cause | 2:34:52 |
| 33. |  SuperbHappyGuy | 26 | Mario Paint: Gnat Attacker Playthrough! | 19:02 |
| 34. | bemwy | 15 | Help me do stuff in Mario Paint... | 12:43 |
| 35. | RickyRockstarTNS | 10 | Mario Paint - SNES playthrough (recorded 2022-01-06) | 12:14 |
| 36. | EFB57 | 10 | [BETAJAM] Sam's theme (Alpha) | 0:54 |
