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| 2. | Ankford | 23,395 | Video Essay | The Religious Symbolism Of Mass Effect | 9:08 |
| 3. | Beta Hunter | 14,355 | Siren Head: Resurrection - Amazing New Siren Head Game! (Plus = Extended Gameplay) - By show-more | 1:54:18 |
| 4. | Linnet's How To | 12,276 | How To Enable Auto Login to EA Online In Mass Effect 2 | 0:18 |
| 5. | 2BSkyen | 10,592 | Overlord, and the Arrival || Mass Effect 2 #28 (the DLC) | 1:52:55 |
| 6. | Rellom Q | 4,076 | THE DANISH NUTS | Let's Play Super Auto Pets | #34 | 31:08 |
| 7. | Isabellas VODs | 3,356 | [LP] Mass Effect 2 ★98 - Dat Reaper-Mensch-Larve [DE/HD+] | 29:06 |
| 8. | ThatInsaneDane | 2,263 | Mass Effect 2 [P14] [END] [full stream] | 2:03:12 |
| 9. | cvs | 1,251 | Mass Effect 2: M 44 Hammerhead Joyride | 5:57 |
| 10. | Persephone | 228 | Mordin Solus Performing Gilbert & Sullivan (Mass Effect 2) | 0:35 |
| 11. | Michael B Gaming | 189 | Mass Effect 2 Legendary Edition : Episode28 Final Episode : Human Larva | 30:51 |
| 12. | Ilovesony10 | 172 | Mass Effect Legendary Edition - Mass Effect 2 Walkthrough The End | 1:03:15 |
| 13. | NördHrafn | 151 | Shep's party [who is the worse dancer?] | 5:54 |
| 14. | RobinKaja | 125 | Mass Effect (DEL 8) | 4:15 |
| 15. | Wolfhead86 | 121 | Mass Effect 2 jack loyalty mission ending | 0:32 |
| 16. | HuVuH | 104 | Day 2/3 loot on Facepunch 10 Small | 1:00 |
| 17. | Vicktor gamer | 91 | MONTAGE BY ME 2 50 SUBS | 3:10 |
| 18. | VO3_BigPizza_YT | 79 | On that we can agree | 0:15 |
| 19. | Kasper Pontoppidan | 56 | Mass Effect 2 Legendary Edition | 57:54 |
| 20. | Kiba Snowpaw | 29 | My Steam Reviews of Mass Effect 2 | 5:34 |
| 21. | FreshWater | 18 | Mass Effect 2 Del 6 - 9 august 22 | 59:49 |
| 22. | Jagermeister101 | 2 | Mass effect 2 | 1:59:57 |
