| 1. | Schaly | 812,714 | Let's Play Mass Effect 2 (blind) - Part 100: The Bonus! | 1:07:17 |
| 2. |  Gloom | 751,485 | TAKE OFF THE DRESS - Seduce Me 2 w/ Yammy | 24:03 |
| 3. |  HAWPOfficial | 597,214 | Mass Effect 2 - Hey Ash Whatcha Playin'? | 1:49 |
| 4. | Angel Alyx | 420,239 | ARRIVAL | Mass Effect 2 Legendary Edition Let's Play Part 25 | 51:08 |
| 5. | Welonz | 420,186 | The Galaxy's Final Hour - Let's Play Mass Effect 2 Legendary Edition Part 68 Ending [PC Gameplay] | 1:09:07 |
| 6. | Geek Remix | 276,920 | Mass Effect Ashley Go Boom | 1:15:46 |
| 7. | SSSniperWolf | 171,954 | Relationship Advice! | 4:49 |
| 8. | The RPG Chick | 155,139 | Let's Play Mass Effect 3 (Blind), Part 2: Prologue | 36:48 |
| 9. |  Yammy | 124,847 | A LITTLE MORE ME IS BACK! 😱 | A Little More Me 2 | Episode 1 | 7:38 |
| 10. | Liera | 122,607 | The Arrival! ... and all assignments - Mass Effect 2 l Veteran difficulty - Pt.28 | 3:20:33 |
| 11. | gamermd83 | 108,657 | Invited To N7 Radio Podcast: Preview! | 4:06 |
| 12. |  AyaAnnyGaming | 88,895 | Mass Effect 2 - Female Shepard - Part 145 (Conversation after ending) | 13:38 |
| 13. |  Esme Silverforce | 73,287 | My Horse And Me 2, Del 2 | 15:43 |
| 14. |  GamerJoob | 70,936 | My First Time Ever Playing Mass Effect 2 | Overlord DLC | Full Playthrough | Xbox Series X | 1:22:24 |
| 15. | Dandifying Gaming | 57,195 | Let’s Bring Our People Home! | Mass Effect 2 Legendary Edition - Part 37 (End) | 1:23:30 |
| 16. | Lomadiah | 44,890 | Hannah & Nilesy - Star Trek #9 - "Blipped You!" | 20:07 |
| 17. | 39daph vods | 41,176 | 39daph Plays Mass Effect 2 - Part 6 (Final) | 1:26:36 |
| 18. | Meghan Yeah | 29,566 | Will I Get The Good or Bad Ending? - Mass Effect 2 / Legendary Edition | 4:54:31 |
| 19. | RikaRieGaming | 25,561 | Mass Effect: Garrus Complete Romance [Creator's Cut - Only M2+M3 Scenes] | 1:34:53 |
| 20. | ApolloIsMyCoPilot | 21,994 | Let's Play! Mass Effect 2 - S36 P6 - 304,942 Sacrifices... | 17:48 |
| 21. | Mirta | 8,548 | Let's Play Mass Effect 2 Part 98 | 15:10 |
| 22. |  Ur Queeen | 7,299 | #11 JAK TO JEST ZGUBIĆ ZIOMKÓW W KOSMOSIE?! / URQUEEEN | 42:03 |
| 23. |  Gab Smolders | 6,717 | Let's Play Siren 1 | Part 30 | 37:28 |
| 24. | GirlFromAus | 6,175 | Mass Effect Live Stream Walkthrough Part 3 - Fist | 1:09:29 |
| 25. | ZombieCleo | 4,186 | Mass Effect: Renegade - 04 | 50:32 |
| 26. | marleygrey | 2,336 | The Arrival [43/FINAL] Mass Effect 2 | 1:34:35 |
| 27. | Classy Katie | 1,240 | ClassyKatie plays MASS EFFECT 2! - Episode 12 | 32:01 |
| 28. |  8 Bites | 784 | MASS EFFECT Walkthrough Part 15 - ALIEN WOMEN CAN'T BE TRUSTED | 37:53 |
| 29. | MsCarsonelle | 509 | Let's Play Mass Effect - Part 23 | 17:30 |
| 30. | Fiaura The Tank Girl | 503 | Mass Effect 2 Resume | 4:26:30 |
| 31. |  Yuni Gaming | 503 | Zaeed's Mission & Recruiting JACK! - MASS EFFECT 2 Blind Playthrough | Part 4 | 2:12:21 |
| 32. | Ceirahmoon | 353 | WE JOIN THE DEMON WAR! REVOLUTION! | {Matthew's Route} #3 | SEDUCE ME 2: THE DEMON WAR | 22:09 |
| 33. |  Ro ✨ | 94 | MASS EFFECT 2 GIVE-AWAY [CLOSED] | 1:19 |
| 34. | Franki | 60 | MASS EFFECT 2 RENEGADE RUN #2 - WE SEE BABE | 26:23 |
| 35. | IvyWinter | 55 | The Best & Worst Role Play Games - Good Game, Bad Game with RobPlaysThatGame! | 11:38 |
| 36. | Nashtya Newb | 49 | Newb plays REMEMBER ME | 40:34 |
| 37. |  skyybunnie | 47 | Insanity Mode Start | 20:07 |
| 38. | KrimsonKitty | 24 | Mass Effect 2 Playthrough Part 39 | 43:04 |
