| 1. |  Digital Foundry | Mass Effect 2 Xbox 360 vs. PlayStation 3 Demo Comparison | 1,562 | Let's Play |
| 2. | SidAlpha | ACERTHORN LAWSUIT IS OVER! We Won! Judge THREW THE CASE OUT | 1,106 | Let's Play |
| 3. |  TetraNinja | Mass Effect 2 Gameplay Walkthrough - Part 1 EPIC OPENING & Prologue Let's Play | 985 | Let's Play |
| 4. | TetraNinja | Mass Effect 2 Gameplay Walkthrough - Part 57 Suicide Mission Ending Let's Play | 607 | Let's Play |
| 5. | Angel Alyx | THE END | Mass Effect 2 Legendary Edition Let's Play Part 24 | 594 | Let's Play |
| 6. | ChristopherOdd | Mr. Odd - Let's Play Mass Effect 2 - Part 63 - Finale [Twitch Archive] | 584 | Let's Play |
| 7. | xcalizorz | Mass Effect 2 Playthrough pt.1 | 472 | Let's Play |
| 8. |  Mapocolops | The Suicide Mission - Mass Effect 2 Ending | Blind Playthrough [Part 21 - ENDING] | 439 | Let's Play |
| 9. | WhatCulture Gaming | 8 Best Video Game Endings You Will Never See On A First Playthrough | 411 | Let's Play |
| 10. | LiteWeight Gaming | The Lazarus Project | Mass Effect 2: Pt. 1 | First Play Through - LiteWeight Gaming | 384 | Let's Play |
| 11. | AGirlAndAGame | Suicide Mission (END) | Mass Effect 2 Legendary Edition Part 21 | First Playthrough | AGirlAndAGame | 369 | Let's Play |
| 12. | LucyusMaximus | Shepard's Return! | Mass Effect 2 Legendary Edition | First Playthrough | 353 | Let's Play |
| 13. | Whimsy Psyche | (First Playthrough) MY SHEPARD! 😭 | Mass Effect 2 - Ep.1 | Let's Play [Veteran] | 345 | Let's Play |
| 14. |  Raketenjansel | Die 10 BESTEN PS3 SPIELE | 336 | Let's Play |
| 15. | Whimsy Psyche | (JACK COSPLAY) The Omega 4 Relay | Mass Effect 2 - Ep.26 | Let's Play [Veteran] | 323 | Let's Play |
| 16. | Angel Alyx | FAMILIAR FACES | Mass Effect 2 Legendary Edition Let's Play Part 2 | 322 | Let's Play |
| 17. | Mapocolops | A Prison Break for Jack & Zaeed's Lust for Revenge - Mass Effect 2 | Blind Playthrough [Part 5] | 321 | Let's Play |
| 18. |  Kim Ellendale | SUICIDE MISSION!! Mass Effect 2 Legendary Edition Blind Gameplay - Part 41 | 314 | Let's Play |
| 19. | ChristopherOdd | Mr. Odd - Let's Play Mass Effect 2 - Part 1 - Odd Shephard is Back! | 314 | Let's Play |
| 20. | Mapocolops | Helping Mordin Solus & Kasumi's Sentimental Heist - Mass Effect 2 | Blind Playthrough [Part 4] | 312 | Let's Play |
| 21. | kaliwali | That Panic Makes Remorse | Mass Effect 2 FINALE | Blind Let's Play Through | 312 | Let's Play |
| 22. | LiteWeight Gaming | Jack | Mass Effect 2: Pt. 9 | First Play Through - LiteWeight Gaming | 306 | Let's Play |
| 23. | Angel Alyx | SHEPARD IS BACK | Mass Effect 2 Legendary Edition Let's Play Part 1 | 305 | Let's Play |
| 24. | kaliwali | When Weakness Turns My Ego Up | Mass Effect 2 | Blind Let's Play Through | Ep. 15 | 298 | Let's Play |
| 25. | Mapocolops | A Wholesome Reunion & Mordin's Search on Tuchanka - Mass Effect 2 | Blind Playthrough [Part 13] | 293 | Let's Play |
| 26. | xcalizorz | Mass Effect 2 Playthrough pt.2 | 291 | Let's Play |
| 27. | kaliwali | Meeting The Professor! | Mass Effect 2 | Blind Let's Play Through | Ep. 4 / Veteran Infiltrator | 291 | Let's Play |
| 28. | kaliwali | Still NOT Listening! | Mass Effect 2 | Blind Let's Play Through | Ep. 3 / Veteran Infiltrator | 288 | Let's Play |
| 29. | darksydephil | Mass Effect 2 HD playthrough pt1 | 288 | Let's Play |
| 30. | LiteWeight Gaming | Stolen Memory (DLC)| Mass Effect 2 Legendary Edition: Pt. 5 | First Play Through - LiteWeight Gaming | 286 | Let's Play |
| 31. | darksydephil | Mass Effect 2 Collector's Edition Unboxing (preview to playthrough) | 283 | Let's Play |
| 32. | AGirlAndAGame | The Krogan Named Grunt | Mass Effect 2 Legendary Edition Part 4 | First Playthrough | AGirlAndAGame | 283 | Let's Play |
| 33. | Kim Ellendale | GOING IN COMPLETELY BLIND!! Mass Effect 2 Legendary Edition Blind Gameplay - Part 1 | 279 | Let's Play |
| 34. | Whimsy Psyche | The Collectors were WHAT now?! | Mass Effect 2 - Ep.14 | Let's Play [Veteran] | 275 | Let's Play |
| 35. | The Sun Queen | This Didn't Go Well ... | Mass Effect 2 Ending | Legendary Edition | | 271 | Let's Play |
| 36. | LiteWeight Gaming | The Professor | Mass Effect 2: Pt. 8 | First Play Through - LiteWeight Gaming | 268 | Let's Play |
| 37. | Whimsy Psyche | Reach & Flexibility | First time playing MASS EFFECT 2 - Ep.13 | Let's Play [Veteran] | 266 | Let's Play |
| 38. | LiteWeight Gaming | Tali | Mass Effect 2 - Legendary Edition: Pt. 2 | First Play Through - LiteWeight Gaming | 262 | Let's Play |
| 39. | Mapocolops | Arriving at Omega & Recruiting Archangel - Mass Effect 2 | Blind Playthrough [Part 3] | 259 | Let's Play |
| 40. | Mapocolops | Kaiden's Unhappy & Jacob Has Daddy Issues, Wonderful - Mass Effect 2 | Blind Playthrough [Part 7] | 254 | Let's Play |
| 41. |  Official EA UK | Mass Effect 2 - Launch Trailer [PlayStation 3] | 253 | Let's Play |
| 42. | kaliwali | Is This A Horror Game?! | Mass Effect 2 | Blind Let's Play Through | Ep. 6 / Veteran Infiltrator | 252 | Let's Play |
| 43. | Kim Ellendale | MY BOI IS BACK BABY!!! Mass Effect 2 Legendary Edition Blind Gameplay - Part 2 | 249 | Let's Play |
| 44. | Mapocolops | Garrus Calibrates His Feelings - Mass Effect 2 | Blind Playthrough [Part 12] | 246 | Let's Play |
| 45. | Mass Effect | Mass Effect 2 - PlayStation 3 Launch Trailer | 245 | Let's Play |
| 46. | PlayStation Access | Mass Effect - That One Choice I Will ALWAYS Make | 242 | Let's Play |
| 47. | LucyusMaximus | Back To The Citadel! (+ Kasumi!) | Mass Effect 2 Legendary Edition Part 2 | First Playthrough | 242 | Let's Play |
| 48. | AGirlAndAGame | Welcome Back Commander | Mass Effect 2 Legendary Edition Part 1 | First Playthrough | AGirlAndAGame | 237 | Let's Play |
| 49. | kaliwali | Ugh, My Heart! | Mass Effect 2 | Blind Let's Play Through | Ep. 2 / Veteran Infiltrator | 236 | Let's Play |
| 50. | kaliwali | So Many Emotions! | Mass Effect 2 | Blind Let's Play Through | Ep. 1 / Veteran Infiltrator | 236 | Let's Play |
| 51. | LiteWeight Gaming | I Am Grunt | Mass Effect 2 Legendary Edition: Pt. 6 | First Play Through - LiteWeight Gaming | 235 | Let's Play |
| 52. | Mapocolops | The New Normandy & Back at the Citadel! Mass Effect 2 | Blind Playthrough [Part 2] | 235 | Let's Play |
| 53. | LucyusMaximus | Omega: Archangel | Mass Effect 2 Legendary Edition Part 3 | First Playthrough | 234 | Let's Play |
| 54. | Mapocolops | The Derelict Reaper & Heretic Station - Mass Effect 2 | Blind Playthrough [Part 20] | 233 | Let's Play |
| 55. |  SargeThePlayer | Zagrajmy w Mass Effect 2 [60 fps] odc. 1 - Drugie życie Sheparda | 231 | Let's Play |
| 56. | Angel Alyx | ARCHANGEL | Mass Effect 2 Legendary Edition Let's Play Part 4 | 231 | Let's Play |
| 57. | eralia | The End...? ✧ Mass Effect 2 First Playthrough ✧ Part 13 | 226 | Let's Play |
| 58. | LiteWeight Gaming | SPACE HAMSTER | Mass Effect 2 Legendary Edition: Pt. 4 | First Play Through - LiteWeight Gaming | 226 | Let's Play |
| 59. | LiteWeight Gaming | Normandy Crash Site | Mass Effect 2 Legendary Edition: Pt. 3 | First Play Through - LiteWeigt Gaming | 224 | Let's Play |
| 60. | LiteWeight Gaming | Garrus | Mass Effect 2 Legendary Edition: Pt. 7 | First Play Through - LiteWeight Gaming | 222 | Let's Play |
| 61. | darksydephil | Mass Effect 2 HD playthrough pt2 | 221 | Let's Play |
| 62. | LucyusMaximus | Lair of the Shadowbroker | Mass Effect 2 Legendary Edition Part 9 | First Playthrough | 220 | Let's Play |
| 63. | Whimsy Psyche | I'm SPEECHLESS | Mass Effect 2 - Ep.25 | Let's Play [Veteran] | 218 | Let's Play |
| 64. | AGirlAndAGame | The Archangel of Omega | Mass Effect 2 Legendary Edition Part 3 | First Playthrough | AGirlAndAGame | 214 | Let's Play |
| 65. | Whimsy Psyche | Illium, here we come! | Mass Effect 2 - Ep.15 | Let's Play [Veteran] | 214 | Let's Play |
| 66. | LiteWeight Gaming | ENDING | Mass Effect 2 Legendary Edition: Pt. 30 | First Play Through - LiteWeight Gaming | 212 | Let's Play |
| 67. | Mapocolops | The Lair of the Shadow Broker - Mass Effect 2 | Blind Playthrough [Part 18] | 210 | Let's Play |
| 68. | LucyusMaximus | Here Comes Jack! | Mass Effect 2 Legendary Edition Part 5 | First Playthrough | 210 | Let's Play |
| 69. | Mapocolops | Grunt's Rite of Passage & Project Overlord - Mass Effect 2 | Blind Playthrough [Part 14] | 209 | Let's Play |
| 70. | Kim Ellendale | I LOST EVERYONE!! Mass Effect 2 Legendary Edition Blind Gameplay - Part 40 | 208 | Let's Play |
| 71. | renwraiths | The beginning of this game is wild! | Mass Effect 2: Legendary Edition | Part 1 | 208 | Let's Play |
| 72. | kaliwali | Final Loyalty Mission | Mass Effect 2 | Blind Let's Play Through | Ep. 24 | 208 | Let's Play |
| 73. | Whimsy Psyche | I CAN'T STOP FANGIRLING | Mass Effect 2 - Ep.4 | Let's Play [Veteran] | 207 | Let's Play |
| 74. | Kim Ellendale | THIS MADE ME QUIT! Mass Effect 2 Legendary Edition Blind Gameplay - Part 10 | 202 | Let's Play |
| 75. | kaliwali | Hides The Face, Lies The Snake | Mass Effect 2 | Blind Let's Play Through | Ep. 9 | 201 | Let's Play |
| 76. | kaliwali | Cerberus Ruins Another Relationship | Mass Effect 2 | Blind Let's Play Through | Ep. 8 | 199 | Let's Play |
| 77. | Toegoff | Let's Play Mass Effect 2 - Part 1: Not a Great Start | 198 | Let's Play |
| 78. | DSPGaming | Mass Effect Femshep Renegade playthrough pt1 | 196 | Let's Play |
| 79. | SargeThePlayer | Zagrajmy w Mass Effect 2 [60 fps] odc. 78 - KONIEC GRY | 196 | Let's Play |
| 80. | zaaap! | My Horse And Me 2: Showdown in Kentucky - ENDE - #14 | Let's Play ★ [GERMAN/DEUTSCH] | 196 | Let's Play |
| 81. | kaliwali | I Delete Data Like You On The Way To Real Errors | Mass Effect 2 | Blind Let's Play Through | Ep. 19 | 196 | Let's Play |
| 82. | Mapocolops | Liara's Favour & Recruiting the Assassin, Thane Krios - Mass Effect 2 | Blind Playthrough [Part 9] | 195 | Let's Play |
| 83. | kaliwali | Jagged Little Pill | Mass Effect 2 | Blind Let's Play Through | Ep. 21 | 195 | Let's Play |
| 84. | Angel Alyx | THE COLLECTORS | Mass Effect 2 Legendary Edition Let's Play Part 6 | 194 | Let's Play |
| 85. | Kim Ellendale | THE ARCHANGEL!! Mass Effect 2 Legendary Edition Blind Gameplay - Part 4 | 191 | Let's Play |
| 86. | Whimsy Psyche | Let's recruit Mordin! | First time playing Mass Effect 2 - Ep.3 | Let's Play [Veteran] | 189 | Let's Play |
| 87. | Welonz | Suicide Mission - Let's Play Mass Effect 2 Legendary Edition Part 65 [PC Gameplay] | 189 | Let's Play |
| 88. | kaliwali | An Eye For An Eye | Mass Effect 2 | Blind Let's Play Through | Ep. 18 | 189 | Let's Play |
| 89. | Mapocolops | The Justicar & The Intercepted Turian Distress Call - Mass Effect 2 | Blind Playthrough [Part 10] | 188 | Let's Play |
| 90. | Schaly | Let's Play Mass Effect 2 (blind) - Part 01: What the Hell!? | 188 | Let's Play |
| 91. | Many A True Nerd | Mass Effect 2 - Part 30 - We Are Legion | 187 | Let's Play |
| 92. | Mapocolops | Project Firewalker & Dr. Okeer's Legacy - Mass Effect 2 | Blind Playthrough [Part 6] | 187 | Let's Play |
| 93. | Living Sun | Let's Play Mass Effect 2 Legendary Edition | Part 34 - Lair Of The Shadow Broker | Blind Gameplay | 186 | Let's Play |
| 94. | AGirlAndAGame | The Hardest Decision | Mass Effect 2 Legendary Edition Part 20 | First Playthrough | AGirlAndAGame | 185 | Let's Play |
| 95. | Whimsy Psyche | (ENDING) Admiral Hackett ❤️ | Mass Effect 2 - Ep.27 | Let's Play [Veteran] | 184 | Let's Play |
| 96. | kaliwali | Shepard! My Friend! | Mass Effect 2 | Blind Let's Play Through | Ep. 14 | 184 | Let's Play |
| 97. | kaliwali | Tali'Zorah vas Normandy nar Rayya | Mass Effect 2 | Blind Let's Play Through | Ep. 13 | 183 | Let's Play |
| 98. | TetraNinja | Mass Effect 2 Gameplay Walkthrough - Part 3 The Normandy II Let's Play | 181 | Let's Play |
| 99. | Kim Ellendale | MEETING JACK! Mass Effect 2 Legendary Edition Blind Gameplay - Part 11 | 181 | Let's Play |
| 100. | LiteWeight Gaming | Kaiden | Mass Effect 2 Legendary Edition: Pt. 10 | First Play Through - LiteWeight Gaming | 179 | Let's Play |
