| 2025-05-10 |  LegendAqua | 933 | LA Plays Mass Effect 2 for the First Time Episode 42: Point of No Return | 0:00 |
| 2025-02-09 | The Game Essayist | 2,720 | The Normandy’s Crew Were Never Friends—And That’s What Made Them Great | 0:00 |
| 2024-11-24 | TheTokalot | 874 | Dont leave me Babe! I want you to stay Liara! - 19/11/2024 | 0:00 |
| 2024-11-17 | Takerai Higgs | 69 | Mass Effect 2 | 0:00 |
| 2024-03-21 | Sargemahal | 12,000 | Mass Effect 2 Legendary Edition Paragon Playthrough Part 22 - An Old Ally | 17:43 |
| 2024-02-03 | V | 149 | Very long mass effect 2 gameplay | 4:53:40 |
| 2023-07-19 | Active Wazza | 207 | Mass Effect 2 Legendary Edition (SUICIDE SQUAD) | 0:59 |
| 2023-05-09 | Dave Pope Music & Games | 28 | Mass Effect 2: The final mission | 1:05:11 |
| 2023-04-16 | Michael Robertson | 2 | Mass Effect 2 - Recruit the Convict: Rare dialogue (Tali, Garrus) | 14:17 |
| 2023-04-11 | Far-No VODs | 53 | Mass Effect 2 - legendary edition - Renegade play through - Part 1 | 2:11:45 |
| 2023-01-24 | RyuLex7 | 112 | No End till 2900 in Puzzles (took me 2.5 hours LMAO) | 2:49:06 |
| 2023-01-12 | Ultria | 3,920 | Mass Effect 2: Stupid woman #shorts | 0:09 |
| 2023-01-02 | TroublesomeTrav | 2,450 | Mass effect is hilarious #funny #shorts #gaming #masseffect #masseffect2 #trending #trendingshorts | 0:20 |
| 2022-09-24 | Uncle Cranky | 48 | Renegade Adept | Mass Effect 2: Legendary Edition | PC (Part 11) | 6:19:40 |
| 2021-12-05 | HazVsPlaythroughs | 1,890 | Mass Effect 2 Legendary Edition FULL PLAYTHROUGH PART 4 | 0:00 |
| 2021-12-02 | TheGamesEntertainer | 68,400 | Guardians of the Galaxy Rendezvous with Milano Escape the Drone Again | 1:05 |
| 2021-07-20 | VelvetThundR | 325 | Mass Effect 2 Legendary Edition - Arrival DLC Ending | 7:00 |
| 2021-07-19 | Aero's Gaming Experiences | 552 | Gaming Story Experience - Mass Effect Legendary Edition (Episode 57) | 44:42 |
| 2021-02-10 | KIWI TALKZ | 19,500 | #80 - Jack Wall Interview (Call Of Duty, Mass Effect, Orchestra, John Williams, Royalties etc.) | 55:27 |
| 2017-03-14 | VG Tech | 25,400 | Mass Effect 2 Xbox 360 vs Xbox One Backwards Compatibility Frame Rate Test | 6:58 |
| 2016-10-15 | Anthropolokitty | 1,380 | Let's Play - Mass Effect 2 - Ep 52 - (Blind) - "Finale Part 2" | 41:44 |
| 2016-06-14 | NZn00bGamer | 348 | A n00b Play's - Mass Effect 2 - Part 54 - Arrival Part 2 | 38:36 |
| 2016-01-29 | Evil Panda | 953 | Gorn Planet - Outpost Tower | Star Trek | Lets Play | Walkthrough | 32:23 |
| 2015-11-02 | English Teacher Plays | 2,480 | Mass Effect - Playthrough Part 6: Planetfall | 45:47 |
| 2014-02-14 | LordMatrim | 8,720 | Mass Effect 2 - Moridin singing | 0:37 |
