| 1. |  KevinGohD | 111,191 | I PLAYED MY FAVORITE SPORTS GAMES OF ALL-TIME IN ONE VIDEO... | 30:22 |
| 2. |  MarlinsBaseball | 78,754 | MLB 06: The Show (Florida Marlins Season) Season Results + Credits | 6:48 |
| 3. | Healy6 | 43,125 | Seeing if MLB 06: The Show is as good as I remember... | 21:06 |
| 4. | KAHOS' RETRO GAMING 3.0 | 36,729 | S3 MLB THE SHOW 06 PS2 NYY - A'S VS. YANKEES - GAME 91 | 53:53 |
| 5. | Nick's Gaming Channel | 32,682 | MLB 06 The Show Career Mode Part 8 | 5:59 |
| 6. | IGN | 30,996 | MLB '06: The Show PlayStation 2 Trailer - Official | 1:22 |
| 7. | Were1974 | 25,039 | MLB 06 The Show (PLAYSTATION PSP) Nationals vs the American League Teams | 1:29:53 |
| 8. | igcompany | 23,848 | MLB 06: The Show - PSP Gameplay (4K60fps) | 10:39 |
| 9. | 10min Gameplay | 18,001 | MLB 06: The Show ... (PSP) Gameplay | 10:00 |
| 10. | someother1ne | 13,744 | MLB 2006 - PS2 (PCSX2) 989 Sports 60 fps | 15:22 |
| 11. | Timmii Gaming Channel | 7,502 | MLB 06 The Show - PS2 2006 (2006 The Best Team vs the Worst Team FLA #30 vs NYY #1) | 1:30:10 |
| 12. | Stream's YouTube Channel | 6,956 | Collecting Every NA PS2 Game - MLB 06': The Show (PS2 Gauntlet #2) | 38:47 |
| 13. | Gyvi World | 6,297 | The Greatest Baseball Game EVER! This made MLB! | 21:17 |
| 14. | Demonic Akumi | 4,752 | MLB 06: The Show (PS2) - Very Very Batty | 1:04:21 |
| 15. | domino866 gameplay | 4,018 | MLB 06 The Show Giants vs Cubs | 1:18:22 |
| 16. | davidb69 | 3,779 | Episode 27 MLB 06 the show PS2 | 56:34 |
| 17. | rocksoldier97 | 3,702 | PS2 Gaming! Episode 2599: MLB '06: The Show | 44:02 |
| 18. | Pichu London Sports | 3,515 | MLB 06 The Show - 2006 AAA All Star Game | 1:02:10 |
| 19. | kukuteku | 3,487 | [PS2] MLB 06 The Show on PCSX2 | 2:09 |
| 20. | AstroCreep | 2,506 | MLB 06: The Show: King of the Diamond | 12:40 |
| 21. | Emmdotfrisk | 2,015 | MLB 06 The Show's Career Mode is DIFFERENT | 33:05 |
| 22. | MultiSt3p | 1,802 | MLB06 The Show (Ps2) Dodgers vs Phillies Part10 | 12:50 |
| 23. | PS2SPORTSINFOSTATION | 1,516 | MLB The Show 06 St. Louis Cardinals vs Detroit Tigers | 48:53 |
| 24. | Free Emulator | 1,362 | MLB 06: The Show | NVIDIA SHIELD Android TV | PPSSPP Emulator [1080p] | Sony PSP | 7:24 |
| 25. | DarkShadowX25 | 1,315 | Jampack Demo Disc Volume 12 Part 6 - MLB 2006 | 26:04 |
| 26. | Joe Vulpis | 1,211 | MLB 06 The Show Franchise Mode Part 5 | 1:27:21 |
| 27. |  ACBlackJ0ck | 1,196 | X-Play - MLB 06 The Show Preview | 3:58 |
| 28. | 30-30 Club - Baseball Video Game Encyclopedia | 1,108 | MLB 06 The Show (PS2) - Gameplay | 1:08:35 |
| 29. | 259 Sports | 1,017 | MLB 06 THE SHOW King Of The Diamond Showcase Crimson VS Cobalt | 1:37:08 |
| 30. | SpencerANoob | 881 | What Franchise Mode Should be! | MLB 06 The Show | 10:00 |
| 31. | GamePlayStation | 866 | MLB 06: The Show -- Gameplay (PS2) | 30:29 |
| 32. | CPUs Play Sports Games | 491 | 2022 World Series Special - MLB 06 The Show - Philadelphia Phillies v Houston Astros | 1:20:08 |
| 33. | billybongsalot | 438 | MLB 06: The Show Home Run Derby (PS2) | 14:16 |
| 34. | NickWagerGames | 363 | I PLAYED THE FIRST EVER MLB THE SHOW! (MLB 06 The Show) | 9:22 |
| 35. | Officer Darkfox | 328 | MLB 06 how to get MONEY (works in every MLB game ever made) | 7:30 |
| 36. | Kasabe | 290 | Welcome to The Show (A Retrospective on MLB 06) - A History of The Show, Episode 4 | 12:06 |
| 37. | Fernando Mora | 272 | MLB 06 The Show Real People Playstation 2 Commercial | 0:31 |
| 38. | TBwellss _Retro_Gaming | 256 | MLB PS2 ( 720 HD ) | 1:14:59 |
| 39. | Null 48 | 247 | MLB 06 The Show Android - PSP Emulator PPSSPP - Gameplay 2022 | 9:07 |
| 40. | HPC OTI | 217 | PPSSPP - PSP emulator - 2018-08-26 MLB 06 | 5:15 |
| 41. | Jay Rock Gaming | 188 | MLB 06 The Show - Red Sox vs Yankees - 1st Year on YouTube Special! This was a close game though!!! | 59:00 |
| 42. | DepressedDugout | 182 | MLB 06 The Show- 1879 Season Roster (Made with PS2 Eyetoy) | 10:16 |
| 43. | Rikman56 | 182 | MLB 06 The Show Bat Flip | 0:08 |
| 44. | Murph Dawg | 177 | MLB 06 The Show: Mets Franchise vs Nationals #3 | 1:08:57 |
| 45. | SLS-Game | 146 | PSP MLB '06 The Show 2006, USA) | 0:31 |
| 46. | Seannosaurus Rex | 122 | Seattle Mariners @ Boston Red Sox | Spring Training [#3] | MLB 06: The Show Gameplay | 1:13:21 |
| 47. | YTC Productions | 112 | MLB 06 The Show Soundtrack Ranked | 5:45 |
| 48. | Stream's VODs | 97 | MLB '06: The Show - I Am Not Good At Baseball Games | PS2 Gauntlet #2 (Twitch VOD) | 1:14:09 |
| 49. | Matthew Hawkings | 74 | Bought MLB 06:The show for PSP, Will it work on a UK PSP | 3:43 |
| 50. | LucianoFootball | 71 | MLB 06 The Show PPSSPP Modo Carreira Parte 3 | 10:19 |
| 51. | Doan's PlayStation Reviews | 63 | Ep. 15 - MLB 06: The Show | 3:43 |
| 52. | d4rkjust1c3 | 55 | MLB The Show 06 - Baltimore Orioles vs. Kansas City Royals - PSP - 1080P | 1:25:27 |
| 53. |  Now Loading Please Wait | 52 | MLB 06 The Show USA - PSP | 0:39 |
| 54. | TheELIOTGAME | 47 | MLB _06_ The Show PlayStation 2 Trailer - ELIOTGAME | 1:20 |
| 55. | Peter Skerritt | 46 | Unsealed: Welcome to The Show | 12:00 |
| 56. |  MicroChirp | 42 | MLB 06: The Show - Preview | 3:40 |
| 57. | Andrew Soto | 24 | MLB 06 THE SHOW NO HITTER! | 0:25 |
| 58. |  Jinwoo Park | 9 | MLB 06: The Show Demo (SCE Studios San Diego, 2006) | 25:58 |
| 59. |  petsasjim1 | 9 | MLB 2006 HYPERSPIN SONY PS2 PLAYSTATION 2 NOT MINE VIDEOSUSA | 0:36 |
| 60. | Graham's Commercials | 6 | MLB The Show 06 Ad | 0:31 |
| 61. | VideoGameX | 1 | MLB 06: The Show | VideoGameX | 10:01 |
