| 1. | GQSmoos | 124 | Let's Play OPUS MAGNUM by Zachtronics #85 | SYNTHETIC MALACHITE (CENTERED PRODUCT CHALLENGE) | 1:05:05 |
| 2. |  Rakupenda | 111 | Quintessential Medium (40G) LOWEST COST | Opus Magnum Journal Issue IX | 3:51 |
| 3. |  Games Mikura | 90 | #90 Opus Magnum embalming fluid | 20:50 |
| 4. | Alex Diener | 75 | Opus Magnum - E75: Replicate | 28:48 |
| 5. | べにこちゃんねる / beniko channel | 59 | 【OpusMagnum】バーチャル錬金！錬金工学者べにこ #61【Vtuber】 | 1:07:50 |
| 6. |  praxeos | 59 | Opus Magnum 47 | 48:57 |
| 7. | Opus Magnum | 58 | (Stream) GTA 5 RP - TAXIчный контент | 1:24:46 |
| 8. |  Keywii Plays | 53 | Keywii Plays Opus Magnum (58) | 44:54 |
| 9. | Lytebringr | 47 | Plagiarism is Bad | Opus Magnum #38 Let's Play with Lyte | 3:19 |
| 10. |  BdaLimey | 46 | Opus Magnum - Episode 11 - Opposing Plots | 5:31:06 |
| 11. | The Proximity | 40 | Opus Magnum Adventure || E38 || Universal Solvant [Let's Play // Finale] | 59:05 |
| 12. | SeaLordJanda | 36 | Journal #1-Van Berlow's Wheel | Opus Magnum #36 | 19:59 |
| 13. | Hog Play | 32 | 32 OpusMagnum Blind Reconstructed Solvent B | 11:32 |
| 14. |  Бульбяш “Bulbash” Помощь с играми и не только. | 32 | Opus Magnum Универсальный растворитель | 4:10 |
| 15. |  no_leaf_clover | 32 | Opus Magnum - Puzzle Game - 32 | 1:06:32 |
| 16. | PanonCotta Games | 31 | Opus Magnum 28 | 48:44 |
| 17. |  PlemYT | 28 | Opus Magnum, Chapter 4, Level 3 | 1:06 |
| 18. |  Diablo | 28 | Chapter 05 - 06 | Opus Magnum | 58:39 |
| 19. |  나으존재 NaeuJohnJae | 27 | 연금술 학술지 탐방 10탄(완) | 42:46 |
| 20. | Deer Darling | 26 | Model Alchemist - Opus Magnum - Let's Play - Part 26 | 24:01 |
| 21. | bigmacdontcare | 25 | This Opus Magnum machine scores higher than Graham’s number | 29:20 |
| 22. | OMGITSABIST | 24 | Week 9 - Transmutation CX - 2022 Opus Magnum Tournament Results Stream | 3:18:10 |
| 23. |  Guillque | 22 | Opus Magnum | #22 - La FIN !!! | 10:04 |
| 24. | R.E.A. | 21 | Bidouillage sur le compendium : Opus Magnum °21 | 44:04 |
| 25. | Kuchiwo Tsugumi | 20 | Thinky Puzzle Game Jam 3 #51 Mouse Wants Cheese | 34:00 |
| 26. | Wolf's Hollow | 19 | Take it step by step | Opus Magnum Ep. 19 (END) | 1:25:00 |
| 27. | Brad Prichard | 19 | Opus Magnum from Zachtronics: Chapter 4 Episode 6 | 1:35:14 |
| 28. | Rydo | 19 | ♐Opus Magnum #19 | 2:59:04 |
| 29. | Lazy Leo | 19 | Адепты эфира - Opus Magnum #19 | 33:34 |
| 30. | 変プレのみずちさん | 17 | 【OPUS MAGNUM #18】これはパズルゲームと略してよいのか？ | 1:02:57 |
| 31. | Mixer Universe | 17 | Opus Magnum #38 Благовонные порошки | 1:07 |
| 32. | Pudding Muffin | 16 | Opus Magnum [16F] The Plot Thickened | 40:52 |
| 33. | シェヴレット・アリス / Chévrette Alice | 14 | 【Opus Magnum】≪3周目≫基本には何度立ち戻っても良い【Vtuber】 | 3:20:09 |
| 34. | A Person Who Exists Somewhere | 14 | Zachtronics - Opus Magnum | END | 21:32 |
| 35. | 箱入りゲーム紹介チャンネル | 14 | 琴葉姉妹ののんびり錬金術～おしまい～ | 12:46 |
| 36. | Shane Firth | 13 | Opus Magnum - Incapacitation Mist - Part 13 | 17:56 |
| 37. |  Casual Click Gaming | 13 | Aldut Stream - Opus Magnum | 1:42:34 |
| 38. | ゲームくまチャンネル | 13 | 【Steam】OPUS MAGNUM #012 | 5:21 |
| 39. | Charlie Chen | 13 | Opus Magnum #13 | 1:37:12 |
| 40. | Lenno Liu | 12 | Opus Magnum Tournament 2021 - Week 1 Results: Improved Explosive Phial | 2:38:26 |
| 41. | Alan Malloy | 12 | Opus Magnum, episode 10.5 | 29:51 |
| 42. | HardcorePlayer | 12 | Opus magnum: lamplight gas | 1:17 |
| 43. | QwizicalQwak | 11 | QwizicalQwak Plays: Opus Magnum (Part 11) - Journal Aches | 1:13:30 |
| 44. | Rand118 | 11 | Final Opus Magnum Stream! Appendix Missions, Part 3 | 2:22:16 |
| 45. | Game Fanatic | 11 | Opus Magnum - Curious Lipstick | 19:09 |
| 46. | Maxi Ch. | 10 | vtuber weaponizes alchemy || #phvtuber #puzzle #shorts | 0:05 |
| 47. | That Design Feel | 10 | Let's Play Opus Magnum | Part 9 | Journal Part 3 | Nostalgic Puzzle Gameplay | 2:28:56 |
| 48. |  臭蕉 | 10 | 🍌🔴Opus Magnum LIVE#10 | 2:44:31 |
| 49. | happysalad | 10 | Gameplay - Opus Magnum, Part 10 - Surprise! | 1:04:59 |
| 50. | Dot_Ty_ | 9 | "Rotary Operator" | 1:22 |
| 51. | orion78fr | 9 | Opus Magnum - partie 9 (finale) | 48:36 |
| 52. | FRX99TSX1jp | 8 | パズルゲーム Opus Magnum - Quintessential Medium (970G, 118, 166) | 1:38 |
| 53. | Sissy Sakura | 8 | Opus Magnum completing Sigmars Garden level 100 | 24:14 |
| 54. | Lord Coggswaffle | 8 | Making Courage Potions in Opus Magnum | 0:30 |
| 55. | Outside The Box {The PowerUser's M.M. D.B.} | 8 | Opus magnum review by OTB | 12:37 |
| 56. | ウタゲ🐰🎃UTAGE GAMES | 8 | 【完結】 #08 勤め先を滅ぼされた錬金術師は、最後に何を作るのか… Opus Magnum 最後の錬成 [ Opus Magnum ] | 1:12:24 |
| 57. | Gepwin | 8 | Opus Magnum 8 Warming Rope (3-3 to 3-6) | 33:45 |
| 58. | Respawn Gaming | 7 | Working with limited space | Opus Magnum ep 7 | 18:48 |
| 59. | DisforDemise | 7 | Fun with Explosives - Opus Magnum LIVE Part 7- 11/01/2024 | 3:25:56 |
| 60. | Nebu Pookins | 7 | Blind Let's Play - Opus Magnum Part 7 - Journal + Sigmar's Garden 2 | 3:21:38 |
| 61. | 사자원숭이 LionTamarin | 6 | 오퍼스 매그넘 Opus Magnum | 0:52 |
| 62. | Tsukanosukeゲーム無実況【無言】チャンネル | 6 | Opus Magnum【第2章】 | 1:35:01 |
| 63. | Aagje | 6 | Finishing the Story | Opus Magnum | 2:00:42 |
| 64. | Vtuberカタリさま | 6 | 【Opus Magnum】エンジン開発垂れ流し。Part3.2。【Vtuberパズルゲーム配信】 | 2:55:06 |
| 65. | cryi75 | 6 | Opus Magnum (part 6) | 3:19:47 |
| 66. | Jerp | 6 | Jerp plays Opus Magnum pt.6 - End of Anateus is just the beginning? (2021-02-05) | 3:29:05 |
| 67. | Amaru Rumiawqa Ch. | 5 | I wanted to stream anything! | 1:26:23 |
| 68. | sinformavx | 5 | Opus Magnum: Balls & Chill kinda night | 2:25:40 |
| 69. | ラミティ | 5 | #5 右脳を鍛えるパズルは柔軟な思考をはぐくむためどんだけやってもOKです。宵闇の錬金術師：難解錬金術パズルゲームに挑む女将【Opus Magnum：オーパス・マグナム】 | 2:44:42 |
| 70. | Gaming With Tor | 5 | Opus Magnum | I think we can beat this today | Part 4 | 2:10:08 |
| 71. | Ensnare's Game Archives | 5 | Opus Magnum - 21/09/21 | 35:52 |
| 72. | Samet The Turk | 5 | Bringing Alchemical Production Into The Home (Opus Magnum) | 1:39:35 |
| 73. | OchiTube | 5 | Stream 🎬 2023-12-15 • Opus Magnum | 3:08:39 |
| 74. | Disco | 5 | 【PC】Opus Magnum #5（ラスト） | 14:51 |
| 75. | Hisao Wada | 5 | Opus Magnum Playlog #05 | 8:48 |
| 76. |  Katumi74 | 5 | Opus Magnum - Puzzle Game Solutions - Chapter 5 - Xbox GamePass | 7:25 |
| 77. | 砂希 | 5 | Opus Magnum #05 １章－４ | 22:12 |
| 78. | project-shasta | 5 | ⚗️ Let's Play Opus Magnum #05 *Ende* | 19:00 |
| 79. | HOUMA 法魔秘桜 | 5 | 【パズル】OPUS MAGNUM #5 | 56:43 |
| 80. |  Staszek iGRAszkowski | 5 | Opus Magnum PL #5 | Ten tytuł dąży do nieskończoności, a przy okazji sprawdzę, jaki jest limit znakó | 36:15 |
| 81. | Wanderbots | 5 | Let's Play Opus Magnum - PC Gameplay Part 16 - Topsy Turvy | 36:24 |
| 82. | Masa Lepori | 4 | A stamina potion, of all things... - Opus Magnum! #3 (VOD) | 2:13:29 |
| 83. | AdApt | 4 | Opus Magnum - Very Dark Thread Solution (Chapter 3, Level 7) | 1:04 |
| 84. | Strelkovka | 4 | Opus Magnum + Noita без гайдов (1726 стрим) | 11:13:49 |
| 85. | Aliensrock | 4 | Optimizing My Factory for Speed AND Size! - Opus Magnum | 16:55 |
| 86. | Haiaiai | 4 | Opus Magnum - Slow computation of a fast growing function | 10:02 |
| 87. | esty8nine | 4 | Opus Magnum - First Look with Esty8nine - Part 4 | 1:10:00 |
| 88. |  Gamer Walkthroughs | 4 | Opus Magnum - Sigmar's Garden, Health Tonic & Stamina Potion (Chapter 1-3) | 30:14 |
| 89. | th_pion | 4 | Opus Magnum - Livestream VOD | 2:26:43 |
| 90. | EnterElysium | 4 | OPUS MAGNUM | STAMINA POTION #03 Amazing Alchemist Game - Let's Play / Gameplay | 43:00 |
| 91. | Jelly Ch. 【Phase Connect】 | 3 | puzzling together and catching up! 🌠 | 1:54:22 |
| 92. | Kernel_ | 3 | Perfect Area Face Powder - Opus Magnum | 1:49 |
| 93. | chinng inta | 3 | ALTF4初見単走 | 4:19:58 |
| 94. | やすYasu | 3 | 【オススメゲーム】OPUS MAGNUM （パズル） | 14:27 |
| 95. | 【おっさん】ぱぱわす | 3 | 【Opus Magnum】＃３錬金術パズルゲーム【おっさん】 | 49:34 |
| 96. | Blind Thought | 3 | Opus Magnum - Alchemical Adequacy 3 | 8:44 |
| 97. | ファルコン・L・ちゃんねる | 3 | 【パズル】FALCONの「Opus Magnum」頭を柔らかく、、、【F&F】 | 34:51 |
| 98. | 中部遊戯 | 3 | 【アーカイブ歓迎】錬金術とプログラミングのゲーム OPUS MAGNUM#3 第2章『失神の霧』~第3章『浄水器』【チャット消滅します】 | 2:01:42 |
| 99. | Wesk Alber Stream Archive | 3 | Opus Magnum VoD Part 3 (Final... oops) | 2:19:11 |
| 100. | Crispy Parsnips VODs | 3 | Opus Magnum - Part 5 - The Final Mega-Hmm | 2:48:46 |
