| 1. |  ItsFunneh | Moving into our new home in Out of Space!! | 4,108,791 | |
| 2. | ItsFunneh | Can we survive outer space? This game is so HARD!! | 3,089,203 | |
| 3. | LetsPlay | Intergalactic Exterminating - Out of Space | Let's Play | 265,747 | Let's Play |
| 4. | LetsPlay | We're Cleaning Our Space Junk - Out of Space | 231,723 | Let's Play |
| 5. | Stumpt | Out of Space - LARGE MAP!!! (4 Player Gameplay) | 128,366 | |
| 6. | Stumpt | Out of Space - CLEAN THE SPACE STATION! (4 Player Gameplay) | 125,662 | |
| 7. | Stumpt | Out of Space - CLEAN OUT THE ALIENS!! (4 Player Gameplay) | 82,456 | |
| 8. | Brian Barczyk | REPTILE ZOO EXPANSION!! I'M ALREADY OUT OF SPACE!! | BRIAN BARCZYK | 69,560 | |
| 9. | IGN | Our Next-Gen Consoles Already Ran Out of Space - Up at Noon Live | 64,139 | |
| 10. | Stumpt | Out of Space - SPIN CLASS!!! (4 Player Gameplay) | 63,943 | |
| 11. | Stumpt | Out of Space - MUTATIONS UPDATE!!! (4 Player Gameplay) | 59,118 | |
| 12. | ChilledChaosGAME | SPACE ROOMMATES FROM HELL! (Out of Space w/ Friends) | 57,450 | |
| 13. | ChilledChaosGAME | STOP SLEEPING ON THE JOB! (Out of Space w/ Friends) | 57,413 | |
| 14. | Stumpt | Out of Space - #2 - FLYING SPACE BUGS?! (4 Player Gameplay) | 56,468 | |
| 15. | Stumpt | Out of Space - WE'VE BEEN COCOONED!!! (4 Player Gameplay) | 48,513 | |
| 16. | Stumpt | Out of Space - RANDOM ITEM CHALLENGE!!! [Part 1] | 48,112 | |
| 17. | Stumpt | Out of Space - ROOMBA MAGIC!!! (4 Player Gameplay) | 46,174 | |
| 18. | Stumpt | Out of Space - CHALLENGE MODE!!! (4 Player Gameplay) | 39,595 | |
| 19. | Schizophrenic Gamer | Summon until out of space... (Summoners War) | 39,210 | |
| 20. | Stumpt | Out of Space - TOTAL FAILURES!!! (4 Player Gameplay) | 38,735 | |
| 21. | Secret Sleepover Society | Jacob and Julia are Becoming Space Roommates in OUT OF SPACE | 36,532 | |
| 22. | Schizophrenic Gamer | Summon until out of space. (Summoners War) | 35,515 | |
| 23. | Stumpt | Out of Space - DIRTY WATER!!! (4 Player Gameplay) | 35,342 | |
| 24. | Stumpt | Out of Space - HEAVY ALIEN CHALLENGE!!! [Part 1] | 33,003 | |
| 25. | Stumpt | Out of Space - TOTAL SUCCESS!!! (4 Player Gameplay) | 32,432 | |
| 26. | Stumpt | Out of Space - Power of Friendship!!! | 25,229 | |
| 27. | Stumpt | Out of Space - RANDOM ITEM CHALLENGE!!! [Part 2] | 24,925 | |
| 28. | Stumpt | Out of Space - IT'S ALIVEEEE!!! | 24,295 | |
| 29. | Austin Burke | Color Out of Space - Movie Review | 22,981 | |
| 30. | Stumpt | Out of Space - Overly Agressive!! | 22,775 | |
| 31. | Stumpt | Out of Space - HARDCORE HOUSEKEEPING CHALLENGE!!! | 22,308 | |
| 32. | Stumpt | Out of Space - Natural Selection! (Patron Pick!) | 20,917 | |
| 33. | Stumpt | Out of Space - NO BEDS FOR US!! | 20,845 | |
| 34. | Stumpt | Out of Space - BUG SPRAY PLAYS!! | 19,725 | Let's Play |
| 35. | Stumpt | Out of Space - EVERYTHING NEEDS POWER!! | 19,119 | |
| 36. | ZeRoyalViking | LOST IN SPACE WITH FRIENDS | Out of Space w/ The Derp Crew | 18,433 | |
| 37. | Stumpt | Out of Space - Leaky Bucket! | 18,422 | |
| 38. | Stumpt | Out of Space - CHALLENGES UPDATE!!! | 17,486 | |
| 39. | Stumpt | Out of Space - GAME OF THRONES!! | 17,119 | |
| 40. | Stumpt | Out of Space - BABY'S FIRST SPACE CLEAN-UP | 16,540 | Let's Play |
| 41. | Stumpt | Out of Space - CIRCLE OF LIFE!! | 16,198 | |
| 42. | Stumpt | Out of Space - LIFE GAVE YOU TIME BOMB TRASH | 16,051 | |
| 43. | DThomasFromNC | HOW TO SET UP INTERNAL HARD DRIVE PS5 + 4TB INSTALL | NEVER RUN OUT OF SPACE!!!! | 15,189 | Guide |
| 44. | cub | Out of Space (Quick Review) | 14,394 | Review |
| 45. | Geekin' with James Hancock | Color Out of Space - Review - Possibly the Best Adaptation of H.P. Lovecraft to Date | 14,193 | |
| 46. | Stumpt | Out of Space - HORRIBLE HOUSEKEEPING!! | 13,590 | |
| 47. | Stumpt | THE BUGS ARE BACK!! - Out of Space [Patron Pick!] | 11,886 | |
| 48. | Stumpt | CAN'T BUY ANYTHING CHALLENGE!! - Out of Space [Patron Pick!] | 10,060 | |
| 49. | GaLm | [1] Out of Space w/ GaLm and Friends | 9,648 | |
| 50. | Regal | Color Out of Space Official Trailer (2020) – Regal HD | 9,342 | Preview |
| 51. | Mr. Rock N Roll | They Don't Disappoint!! | NINGEN ISU / The Colour out of Space (人間椅子 / 宇宙からの色) | REACTION | 8,771 | |
| 52. | AyChristeneGames | OVERCOOKED IN SPACE??? | OUT OF SPACE W/ @Teecup181 @ThePrincessOfVariety @ThatsoAlyKat | 8,107 | |
| 53. | pReview'd | Color out of Space - Trailer Reaction | 7,825 | Preview |
| 54. | Mike's Book Reviews | The Colour Out of Space by H.P. Lovecraft Is The Zenith of Cosmic Body Horror (Book & Movie Review) | 6,035 | Review |
| 55. | bofur_hs | Duping Shellementals Until We're Out of Space! | 5,906 | |
| 56. | Pepp's Picks | Out of Space Review | Angry co-op action | 5,325 | Review |
| 57. | Logitech G | HOW DID IT GO SO WRONG? - Let's play Out of Space | 4,518 | Let's Play |
| 58. | ArtByAdrock | I Ran Out Of Space... It's Moving Time | 4,464 | |
| 59. | Nookrium | Out of Space - [w/ Katherine of Sky - DJPaultjeD - TheGeekCupboard] | 4,427 | |
| 60. | AyChristeneGames | OUT OF SPACE COLLAB W/ TEECUP181 | 2,368 | |
| 61. | AyChristeneGames | OUT OF SPACE GAME COLLAB W/ TEECUP181 PART 2 | 2,192 | |
| 62. | Stumpt Rik | HURRY UP AND DELIVER ALREADY | Out of Space #1 | (Weekly Challenge) | 1,954 | |
| 63. | Calypso | Color Out of Space - Cosmic Horror Done Right | 1,784 | |
| 64. | Stumpt Rik | YOU ONLY GET ONE! | Out of Space #2 | (Weekly Challenge) | 1,559 | |
| 65. | Space Game Junkie | Out of Space - What the....? - Let's Preview | 1,362 | |
| 66. | OldPlay | NEWBS PLAY OUT OF SPACE | OUT OF SPACE 2 PLAYER GAMEPLAY | 1,297 | |
| 67. | TheEricButts | REACTION! Color Out of Space Trailer #1 - Nicolas Cage Lovecraft Movie 2020 | 1,240 | Preview |
| 68. | InDepth Gaming! | Out of Space: Couch Edition Review on Xbox | 1,225 | Review |
| 69. | Tekgamer's World | Nintendo Switch Storage Hacks! Maximize Space for Gaming 🎮🚀 #shorts | 1,199 | |
| 70. | Nerdout Shelter | Out of Space #01 | Nintendo Switch Gameplay | 1,094 | |
| 71. | worthplayingvideos | Out of Space [Switch/PS4/XOne/PC] Teaser Trailer | 907 | |
| 72. | Hip HopTV | Quando Rondo - Out of Space | Reaction | 795 | |
| 73. | The Late Late Horror Show | Color Out Of Space 2019 Full Movie Review TLLHS | 735 | Review |
| 74. | HowlDirk | SPACE JANITORS! | Out of Space - FNWTM | 719 | Let's Play |
| 75. | The Game Show | Play PS5 Games on a PS4 + The Best Features from the PS5 April Update | 698 | |
| 76. | Soundtrack Tracklist | Color Out of Space Soundtrack Tracklist | H.P. Lovecraft's Color Out of Space (2020) Nicolas Cage | 614 | |
| 77. | Space Game Junkie | Out of Space - Not Fun Solo - Let's Try | 542 | |
| 78. | Jacob Anders Reviews | Color Out Of Space - Movie Review (H.P. Lovecraft Horror Movie!) | 500 | Review |
| 79. | Kyle Streams Stuff | Out of Space | In Space Nobody Can Hear You Clean | 462 | |
| 80. | Anthony Cheeseborough (Semantics) | Tamahome plays Out of Space(speedy mix) | 381 | |
| 81. | Hip HopTV | Quando Rondo - Out of Space | Reaction | 360 | |
| 82. | Human Echoes | Color Out of Space (2020) Review - Richard Stanley Returns | 356 | Review |
| 83. | The Minion 256 | Out of Space: Couch Edition - 10 Minutes of Gameplay | 331 | |
| 84. | Nerdout Shelter | Out of Space #02 | YouTube Shorts #shorts | 309 | |
| 85. | XBLA Fans | Out of Space: Couch Edition Quick Taste | 280 | |
| 86. | Variety Princess | FIRST TIME PLAYING OUT OF SPACE | W/ @Teecup181 @AyChristeneGames & @ThatsoAlyKat | 271 | |
| 87. | Bird Catcher | Out of Space #1 - Viscera FTL | 254 | |
| 88. | Bird Catcher | Out of Space #4 - Merry Christmas :P | 221 | |
| 89. | DannyHauck | Out of Space Gameplay STINKY?! #shorts | 218 | |
| 90. | WildTangent | Out of Space | 206 | |
| 91. | Nerdout Shelter | Out of Space #03 | YouTube Shorts #shorts | 204 | |
| 92. | ZEYA GAME PLAYER | 2021 - Out of space for the first time! #subwaysurfers #space #2021 #wrapped | 186 | |
| 93. | Gaming with Family | Out of Space with Family, Episode 1 - "That was zen mode?" | 181 | |
| 94. | Mad$um | This game is hard - Out of Space:Couch Edition - Xbox live gold April | 171 | |
| 95. | VIVY Has A Dream | [GAME REVIEW] OUT OF SPACE - LET'S MOVE IN A SPACESHIP | 155 | Review |
| 96. | Shook50 | Out of Space New Day, New Game (Cleaning a Spaceship) | 155 | |
| 97. | Double Jump Snails | Snail Pack is Outta Space | 152 | |
| 98. | Mad$um | Out of Space: Couch Edition - Xbox live gold - April's game | Tutorial | 131 | Tutorial |
| 99. | Slayheim | The Colour Out of Space (By H.P. Lovecraft) | 131 | |
| 100. | Shawn K The King | Out of Space Couch Edition Review / First Impression (Playstation 5) | 124 | Review |
