| 1. |  Rocket Beans Let’s Play | 35,749 | Der Griff der schwarzen Pest | Pathologic 2 mit Simon | 1:27:59 |
| 2. | Rocket Beans Gaming | 20,125 | Ein Survival-Horror-Kampf gegen die Pest | Pathologic 2 mit Gregor | 1:42:48 |
| 3. | GamersGlobal | 13,144 | Pathologic 2 im Test: Kranker Horror-Trip (German) | 8:42 |
| 4. | CarbonCola | 11,131 | Pathologic 2 in 60 seconds #pathologic2 #pathologic #gaming #games #shorts | 1:00 |
| 5. | EurogamerGermany | 9,920 | Pathologic 2 - Release Date Trailer | 1:31 |
| 6. | Ludophiles | 5,229 | Pathologic 2 The Marble Nest DLC Full Playthrough / Longplay / Walkthrough | 1:24:01 |
| 7. | Hooked | 2,129 | Pathologic 2 & Supraworld angespielt! (Stream vom 01.08.) | 1:56:45 |
| 8. | Boitel | 1,898 | Bester skurriler Thriller! 😷 Let's Test PATHOLOGIC 2 💀 Gameplay (deutsch/german) | 42:07 |
| 9. | Deevoz | 1,714 | Let's Play Pathologic 2 - Episode 52 | Voice ASMR | Playthrough | 30:55 |
| 10. | DK Productions | 973 | GameGuru MAX: Winter is coming (Snow Particles Test) | 1:56 |
| 11. | IrregularAce | 890 | VG vs RL - The real life equivalent to Pathologics plague | 22:05 |
| 12. | Takerst | 848 | My PASSION to Community causes TROUBLED Moments | Pathologic 2 #shorts | 0:27 |
| 13. | Makiageki | 613 | Pathologic 2 - wer ist der Achte | 38:48 |
| 14. | Scotchy | 526 | Pathologic 2 [Day 2] Livestream in Deutsch und alt-aramäisch | 42:57 |
| 15. | XboxDynasty | 470 | Pathologic 2 - Die ersten 20 Minuten in 4K | 21:31 |
| 16. | mikeontheinternet | 387 | PATHOLOGIC 2 GAMEPLAY DEUTSCH 01 DIE ERSTE STUNDE - PS4 PRO | 59:21 |
| 17. | Eisen | 304 | Pathologic 2 (МОР 2019) - Прожорливый Ремейк [Обзор] | 4:31 |
| 18. | OdinsTests | 256 | Angezockt | Pathologic 2 [4K] [PS4 Pro] | 14:20 |
| 19. | HeadlessHideout | 213 | Pathologic 2 [Episode 25] Die Uhr tickt [GER?] [Uncut] | 22:12 |
| 20. | SmartWargames | 88 | Pathologic 2 - Walkthrough Part 2 (No Commentary) | 4:13:34 |
| 21. | FatLP | 73 | Let's Test Pathologic 2 -deutsch- Wer bin ich, wo will ich hin und warum überhaupt? | 1:16:06 |
| 22. | Aloexis | 59 | Pathologic 2 - Demo - Stream vom 26.04.2019 - Tana Testet | Aloexis | 1:35:21 |
| 23. | Hossein Askari | 52 | Ethics | 6:19 |
| 24. | The technique dobi | 49 | Pathologic 2 (Psycho-Horror) - Teil 1 des Livestream - (FaceCam)(Deutsch/German) | 21:10 |
| 25. | Hasann TV | 27 | Pathologic 2 - FIRST Gameplay Demo (PAXWest 2017) | 5:45 |
| 26. | Mad Dog Velare | 21 | PATHOLOGIC 2 - Tag 1 | 4:05:52 |
| 27. | DesignbyNorman | 13 | #GIVEAWAY #Verlosung #Gewinnspiel #Pathologic2 #Horror Steam key Verlosung. | 0:27 |
| 28. | Xbox Family Guy | 13 | ⏩ Pathologic 2 ⏪ 30 Minuten mit : Die große Spielebibliothek von A-Z ‼️ Xbox one / Series X | 33:46 |
| 29. | Zock Palast | 9 | PATHOLOGIC 2 "Official E3 FIRST DEMO Gameplay & Trailer" HORROR GAME | PS4 / XBOX / PC | HD | 5:44 |
| 30. | Sebastian Küster | 1 | [GER/ENG] 12 Tage Zeit | 1:46:28 |
| 31. | Ryuzaziki | 0 | Sonntesten: Pathologic 2 | 1:15:19 |
