| 1. |  outsidexbox | 54,038 | Weird Plague Horror Pathologic 2 in Show of the Week | 27:44 |
| 2. | n o o k | 35,352 | Pathologic2 Ambience - Medium Rain & Kozhevenny Background | 1:00:15 |
| 3. | Jimち ASMR | 30,403 | Pathologic 2 ASMR Surgeon Roleplay | Medical Lecture w/ Artemy Burakh | 46:06 |
| 4. | First Outpost | 9,210 | Pathologic 2 - Review and Analysis | 36:33 |
| 5. | Trophy Hunter Gaming | 8,847 | Pathologic 2 Walkthrough - All Pathologic 2 Trophies - Day 5 - Pathologic 2 Platinum Trophy Guide | 26:35 |
| 6. | ReformistTM | 4,364 | "You Can't Save Everyone" Pathologic 2 Gameplay PC Let's Play Special Feature | 28:09 |
| 7. | SCREEN STARS | 3,199 | Pathologic 2: PS4 Review | 8:47 |
| 8. | Mamushi | 2,720 | Pathologic 2 - A Must Have Video Game Experience | 12:22 |
| 9. | Randomise User: The Best Indie Games | 2,167 | PATHOLOGIC 2: CREEPY PLAGUE KIDS! | Open-world survival thriller | Pathologic 2 gameplay alpha | 36:54 |
| 10. | Ken Wainwright | 2,028 | Pathologic 2: Diurnal Ending | 0:48 |
| 11. | Boringest Gaming Channel | 1,481 | Pathologic 2: Xbox Series S Gameplay | 4:33 |
| 12. | W92Baj - Minecraft and games | 1,214 | Pathologic 2 - Intro and first look. WTH | 42:45 |
| 13. | RemovableSanity | 1,161 | Pathologic 2 Review on Xbox - Full HD | 15:58 |
| 14. | Rei Morvant | 865 | I have to SAVE people?! / First Playthrough PATHOLOGIC 2 #1 | 36:30 |
| 15. | Dwaggienite | 827 | #AchieveHunt - Pathologic 2 (W10) - 1000G in 27.5s! | 1:45 |
| 16. | Dave Berry | 694 | Pathologic 2 (Part 95) | 20:17 |
| 17. | Roggor | 688 | Pathologic 2 Alpha Let's Play #3 - NIGHT ONE | 26:37 |
| 18. | Video Game Room | 477 | Indie Games Exhibit 9 (10 Indies) | 8:18 |
| 19. | Frazzz | 340 | Pathologic 2 Gameplay - Smash Look! | 29:40 |
| 20. | Malkaiah Stream VODs | 232 | Pathologic 2 [PS5] Bonus Session - The Other Endings | 1:38:11 |
| 21. | The Rabbit Hole | 219 | Pathologic 2 is too Big for my Dumb brain | 34:38 |
| 22. | Crissytina | 194 | Pathologic 2 - Lights out..THE END | 39:52 |
| 23. | The Veteran Player | 188 | Pathologic 2 | RX 580 8G (eGPU) | i7-4870HQ | Benchmark | Ultra Settings on MacBook Pro | 18:43 |
| 24. | AlwaysLukeVT | 173 | THIS GAME LOOKS INTERESTING! | Pathologic 2 Gameplay (ENG,PC) | 1:23:28 |
| 25. | War Maps | 158 | PATHOLOGIC 2 - Gameplay Trailer - DARK SURVIVAL THRILLER 2019 | 9:42 |
| 26. | BUG | 111 | Pathologic 2 - Part 7 | 2:09:15 |
| 27. | Denyard | 102 | I Don't Want Your Drugs Kind Sir! | Pathologic 2 | Part 1 | 0:00 |
| 28. | Roman plays. | 102 | Pathologic 2. Headphones advised. | 6:27:31 |
| 29. | Respawning | 96 | The Bear's Den | Pathologic 2 review | 9:47 |
| 30. | Lauren | 85 | Pathologic 2 Part 2 (There's Been A Murrrrrder!) | 44:25 |
| 31. | Serious Gaming | 80 | PATHOLOGIC 2 Trailer (2017) Open World Survival Horror Game | 6:25 |
| 32. | NightmareModeGo | 74 | Just A Little Stream // Pathologic 2 - 31/03/20 | 2:50:46 |
| 33. | Purin | 64 | Pathologic 2 | 2:39:30 |
| 34. | EmBaTaTV | 60 | Pathologic 2 (Какво се Случва в Тази Игра) | 41:33 |
| 35. | HatCHeTHaZ | 55 | HatCHeTHaZ Plays: Pathologic 2 [PS4 Pro] | 1:41:08 |
| 36. | CraftDAnimation | 54 | Before You Buy - Pathologic 2 (PC) | 39:27 |
| 37. | CheapSkate Gaming | 48 | Pathologic 2 " Great Games under $3" | 7:16 |
| 38. | ItsP | 46 | Home Owner Starves To Death - Pathologic 2 | #8 | 50:42 |
| 39. | CrumbleChris | 44 | Pathologic 2 "Trains, Stowaways, and Fighting" [EP02] | 23:03 |
| 40. | We Play Games! | 39 | Pathologic 2 - Launch Trailer | 2:25 |
| 41. | roxyellen_ | 31 | Pathologic 2 first playthrough #2 | 3:51:36 |
| 42. | Hyp3r RyZe | 28 | pathologic 2 take two after pc crash! bring it on game!!!!! | 3:38:31 |
| 43. | 2Game | 16 | Pathologic 2 - Theater of Gorkhon Pre-Order Trailer | 1:41 |
| 44. | Dougie The Reverse Pro Gamer | 10 | First Look at Pathologic2 on PS4 #pathologic2 | 1:49:16 |
| 45. | VarietyDefenceForce | 10 | VGUK Lucky Kieran - Pathologic 2 - Confused | 52:47 |
| 46. | Crossplatform Gamer Master Race | 7 | Pathologic 2 - Opening (3440x1440 RTX 2080 i9 9900K Ultra) | 34:21 |
| 47. | Anthony Andrews | 6 | Pathologic 2 FIRST Gameplay Demo New Open World Horror Game | 5:44 |
| 48. | Captain Dagon's World Of Fun Stuff | 3 | Pathologic 2 - Live gaming - no comentary | 1:29:39 |
| 49. | Pocket Penguin | 3 | THEY DON'T LISTEN !!! (PS4) P2 | 2:06:36 |
| 50. | Zsuti90 | 2 | Kipróbáljuk rovat #1 - Pathologic 2 | 2:05:23 |
| 51. | cosmic Penguin | 2 | Pathologic 2: Mmmmmm fire: Pt1 | 40:14 |
| 52. | Friday24 | 2 | Pathologic 2 - GamePass Roulette #78 | 21:52 |
