| 1. |  CoxClips | 77,565 | Jesse Plays Potionomics | Part 2 | 2:03:27 |
| 2. | Michaela Laws | 53,835 | 『Michaela Plays』Potionomics - Finale | 47:35 |
| 3. | Quasimofo | 49,088 | Let's Play Potionomics (Blind) Part 24 FINALE - The Final Competition and Paying Off My Debt! | 48:47 |
| 4. | Pinstar | 19,089 | Pinstar Plays Potionomics: The Finale! | 1:00:23 |
| 5. | XSEEDgames | 10,345 | Potionomics: Masterwork Edition - Announcement Trailer | 1:10 |
| 6. | MadRadIan | 507 | Potionomics #39: The Final Haggle! | 32:11 |
| 7. | ETA MediaGroup | 461 | Potionomics [028 - Haggle With The Best of 'Em] ETA Plays! | 15:54 |
| 8. | Indie Game Lover | 253 | Manage Potions & Deck-build for Gains | Potionomics | First Look Indie Game | 23:18 |
| 9. | aulddragon | 208 | Potionomics — Part 49 - Helping Xid With Her Writing | 33:09 |
| 10. | Games with Dialogue | 134 | Potionomics - Double Bubble, Toil And Troubles - Let's Play Ep. 7 | 1:04:44 |
| 11. | Nane Niwa Vods | 118 | VTuber Nane Niwa Let's Play Potionomics! [Episode 9] FINALE??? LETS BEAT THIS BOSS #WORMARMY | 2:26:54 |
| 12. | NanashiGaming96 | 101 | Let's Play - Potionomics | Winning the 1st Competition - Part 2.3 | 20:30 |
| 13. | RedxxEagle | 63 | Twitch Let's Play - Potionomics - Day 9 | 25:29 |
| 14. | Wrath of Zalis | 53 | Run a Shop, Craft Potions, and Flirt with People - Let's Play Potionomics | 1:05:58 |
| 15. | Peter Moxilin | 36 | Let's Play Potionomics, Part 13 (Livestream 5/3) | 1:45:28 |
| 16. | Wristlocke | 25 | Potionomics first 10 days - Let's play part 1 | 3:53:55 |
| 17. | Headhunter Gaming | 25 | Hunter Plays: Potionomics | 54:23 |
| 18. | Stoic | 12 | Potionomics | Let's Play Part 2 - New Day, New Plays | 28:10 |
| 19. | theballguy | 2 | Let's Play Potionomics Part 29 | 25:59 |
| 20. | Rydo | 0 | Potionomics New or Trending Game | 0:00 |
