| 1. |  Nerdy_Emily_ | 45 minutes with Prototype 2 UNCUT (Gameplay part 1 of 3) | 3,088 | |
| 2. | FloTutorial | Prototype 2: CRASH/STÜRZT ab BEHEBEN! | Problemlösung | Crash fix Deutsch | 2022 | 968 | |
| 3. | Nerdy_Emily_ | 45 minutes with Prototype 2 UNCUT (Gameplay part 2 of 3) | 697 | |
| 4. | Katana | Prototype 2 Walkthrough | Part 12 | Hard | The Lab Rat | 669 | Walkthrough |
| 5. | Katana | Prototype 2 Full Walkthrough Longplay | Hard | Final Cut | 421 | Walkthrough |
| 6. | Nerdy_Emily_ | 45 minutes with Prototype 2 UNCUT (Gameplay part 3 of 3) | 407 | |
| 7. | Hellgaming | Let's Play Prototype 2 [#5] [Blind/FullHD] Hydra Bossfight & Juggernaut Bossfight | 314 | Let's Play |
| 8. | Katana | Prototype 2 Walkthrough | Part 1 | Hard | Prototype Recap | 259 | Walkthrough |
| 9. | Nerdy_Emily_ | Prototype 2 - UNCUT - Bonus Video 1 | 230 | |
| 10. | Katana | Prototype 2 Walkthrough | Part 20 | Hard | Operation: Keyhole | 208 | Walkthrough |
| 11. | Hellgaming | Let's Play Prototype 2 [#1] [Blind/FullHD] Ausbruch | 169 | Let's Play |
| 12. | Katana | Prototype 2 Walkthrough | Part 2 | Hard | Meet Your Maker | 165 | Walkthrough |
| 13. | Katana | Prototype 2 Walkthrough | Part 4 | Hard | The Strong Survive | 138 | Walkthrough |
| 14. | Katana | Prototype 2 Walkthrough | Part 10 | Hard | Operation: Manticore | 136 | Walkthrough |
| 15. | Katana | Prototype 2 Walkthrough | Part 44 | Hard | Murder Your Maker [Ending] | 136 | Walkthrough |
| 16. | Katana | Prototype 2 Walkthrough | Part 5 | Hard | Operation Flytrap | 132 | Walkthrough |
| 17. | Katana | Prototype 2 Walkthrough | Part 7 | Hard | Operation: Black Tulip | 123 | Walkthrough |
| 18. | Hellgaming | Let's Play Prototype 2 [#3] [Blind/FullHD] Auf der Jagd | 123 | Let's Play |
| 19. | Katana | Prototype 2 Walkthrough | Part 25 | Hard | A Nest of Vipers | 120 | Walkthrough |
| 20. | Katana | Prototype 2 Walkthrough | Part 3 | Hard | Resurrection | 110 | Walkthrough |
| 21. | Katana | Prototype 2 Walkthrough | Part 6 | Hard | Operation: Orion's Belt | 108 | Walkthrough |
| 22. | Katana | Prototype 2 Walkthrough | Part 29 | Hard | Alpha Wolf | 105 | Walkthrough |
| 23. | Nerdy_Emily_ | Prototype 2 - UNCUT - Bonus Video 2 | 101 | |
| 24. | Katana | Prototype 2 Walkthrough | Part 32 | Hard | Predator and Prey | 100 | Walkthrough |
| 25. | Katana | Prototype 2 Walkthrough | Part 27 | Hard | Operation: Vivid Future | 99 | Walkthrough |
| 26. | Hellgaming | Let's Play Prototype 2 [#2] [Blind/FullHD] Ein Spaziergang im Park | 99 | Let's Play |
| 27. | Katana | Prototype 2 Walkthrough | Part 23 | Hard | Operation: Jack-Of-All-Trades | 96 | Walkthrough |
| 28. | Hellgaming | Let's Play Prototype 2 [#7] [Blind/FullHD] Projekt Orion | 96 | Let's Play |
| 29. | Katana | Prototype 2 Walkthrough | Part 34 | Hard | Operation: Spotted Cat | 93 | Walkthrough |
| 30. | Hellgaming | Let's Play Prototype 2 [#12] [Blind/FullHD] Noch ein Mutant weniger | 89 | Let's Play |
| 31. | Katana | Prototype 2 Walkthrough | Part 36 | Hard | Operation: Long Horizon | 88 | Walkthrough |
| 32. | Katana | Prototype 2 Walkthrough | Part 14 | Hard | Operation: Clean Sweep | 87 | Walkthrough |
| 33. | Katana | Prototype 2 Walkthrough | Part 42 | Hard | Lost in the System | 87 | Walkthrough |
| 34. | Katana | Prototype 2 Walkthrough | Part 31 | Hard | The Descent | 85 | Walkthrough |
| 35. | Katana | Prototype 2 Walkthrough | Part 8 | Hard | Brain Drain | 82 | Walkthrough |
| 36. | Hellgaming | Let's Play Prototype 2 [#16] [Blind/FullHD] Bossfight Goliath und ein neuer Kontakt | 82 | Let's Play |
| 37. | Katana | Prototype 2 Walkthrough | Part 13 | Hard | Salvation | 81 | Walkthrough |
| 38. | Hellgaming | Let's Play Prototype 2 [#14] [Blind/FullHD] Mission Leitwolf | 81 | Let's Play |
| 39. | Katana | Prototype 2 Walkthrough | Part 9 | Hard | Project Long Shadow | 80 | Walkthrough |
| 40. | KoAlA | Чит для Prototype 2 - все что вам необходимо знать! | 79 | |
| 41. | Katana | Prototype 2 Walkthrough | Part 38 | Hard | Operation: Clockwork | 79 | Walkthrough |
| 42. | Hellgaming | Let's Play Prototype 2 [#13] [Blind/FullHD] Gemetzel im Bau | 77 | Let's Play |
| 43. | Katana | Prototype 2 Walkthrough | Part 35 | Hard | Last Resort | 76 | Walkthrough |
| 44. | Katana | Prototype 2 Walkthrough | Part 28 | Hard | A Maze of Blood | 76 | Walkthrough |
| 45. | Katana | Prototype 2 Walkthrough | Part 24 | Hard | Operation: Red Glacier | 76 | Walkthrough |
| 46. | Katana | Prototype 2 Walkthrough | Part 15 | Hard | The Mad Scientist | 75 | Walkthrough |
| 47. | Hellgaming | Let's Play Prototype 2 [#17] [Blind/FullHD] Die Rote Zone | 75 | Let's Play |
| 48. | Katana | Prototype 2 Walkthrough | Part 19 | Hard | Enemies and Allies | 75 | Walkthrough |
| 49. | Katana | Prototype 2 Walkthrough | Part 40 | Hard | Divine Intervention | 74 | Walkthrough |
| 50. | Katana | Prototype 2 Walkthrough | Part 37 | Hard | Operation: Stun Circuit | 73 | Walkthrough |
| 51. | Katana | Prototype 2 Walkthrough | Part 39 | Hard | Fly in the Ointment | 73 | Walkthrough |
| 52. | Katana | Prototype 2 Walkthrough | Part 30 | Hard | Fall from Grace | 72 | Walkthrough |
| 53. | Katana | Prototype 2 Walkthrough | Part 11 | Hard | Feeding Time | 70 | Walkthrough |
| 54. | King Of Games | #Prototype 2 Серия-1 | 69 | |
| 55. | Katana | Prototype 2 Walkthrough | Part 17 | Hard | Natural Selection | 68 | Walkthrough |
| 56. | Katana | Prototype 2 Walkthrough | Part 26 | Hard | Taking the Castle | 67 | Walkthrough |
| 57. | Hellgaming | Let's Play Prototype 2 [#4] [Blind/FullHD] Mission Braindrain | 67 | Let's Play |
| 58. | Katana | Prototype 2 Walkthrough | Part 22 | Hard | The White Light | 66 | Walkthrough |
| 59. | Hellgaming | Let's Play Prototype 2 [#8] [Blind/FullHD] Projekt Orion Phase 2 | 64 | Let's Play |
| 60. | Hellgaming | Let's Play Prototype 2 [#20] [Blind/FullHD] Heli Eskorte | 63 | Let's Play |
| 61. | Katana | Prototype 2 Walkthrough | Part 43 | Hard | A Labor of Love | 62 | Walkthrough |
| 62. | Katana | Prototype 2 Walkthrough | Part 16 | Hard | Orion Phase Two | 62 | Walkthrough |
| 63. | Hellgaming | Let's Play Prototype 2 [#19] [Blind/FullHD] Heller is back | 62 | Let's Play |
| 64. | Katana | Prototype 2 Walkthrough | Part 21 | Hard | A Stranger Among Us | 62 | Walkthrough |
| 65. | Katana | Prototype 2 Walkthrough | Part 18 | Hard | The Airbridge | 62 | Walkthrough |
| 66. | Hellgaming | Let's Play Prototype 2 [#6] [Blind/FullHD] Erlösung | 61 | Let's Play |
| 67. | Katana | Prototype 2 Walkthrough | Part 33 | Hard | Burned from Memory | 60 | Walkthrough |
| 68. | Katana | Prototype 2 Walkthrough | Part 41 | Hard | Operation Firehawk | 60 | Walkthrough |
| 69. | Hellgaming | Let's Play Prototype 2 [#18] [Blind/FullHD] Moment mal ich muss telefonieren | 58 | Let's Play |
| 70. | Hellgaming | Let's Play Prototype 2 [#10] [Blind/FullHD] Action in der Grünen Zone | 56 | Let's Play |
| 71. | Hellgaming | Let's Play Prototype 2 [#22] [Blind/FullHD] Gib mir meine Tochter !! | 52 | Let's Play |
| 72. | Katana Longplays | Prototype 2 Full Walkthrough Longplay | Hard | Final Cut | 50 | Walkthrough |
| 73. | Nerdy_Emily_ | Prototype 2 - UNCUT - Bonus Video 3 | 49 | |
| 74. | Hellgaming | Let's Play Prototype 2 [#9] [Blind/FullHD] Koenig ist ein Mutant | 49 | Let's Play |
| 75. | Hellgaming | Lets Play Prototype 2 [#15] [Blind/FullHD] Roland geht es an den Kragen | 48 | Let's Play |
| 76. | Retard Gaming | » Prototype2 « Episode 1 » Der Anfang « HD » | 46 | Show |
| 77. | Hellgaming | Let's Play Prototype 2 [#11] [Blind/FullHD] Evak in der Grünen Zone | 43 | Let's Play |
| 78. | Hellgaming | Let's Play Prototype 2 [#23] [Blind/FullHD] Das Große Finale | 42 | Let's Play |
| 79. | Hellgaming | Let's Play Prototype 2 [#21] [Blind/FullHD] 2 Väter unter sich | 34 | Let's Play |
| 80. | ytdlder | Prototype 2 | 23 | |
| 81. | Michael Mikula | Prototype 2 | 15 | |
| 82. | KoAlA | Прохождения Prototype 2 | 14 | |
| 83. | KoAlA | СТРИМ Prototype 2-конец сюжетной линии | 10 | |
| 84. | King Of Games | #prototype-2 | 9 | |
| 85. | KoAlA | Новая игра в прототип 2 но со всеми спасобностими | 9 | |
| 86. | King Of Games | #prototype-2 | 7 | |
| 87. | King Of Games | Prototype 2 Прохождение Серия 6 | 6 | |
| 88. | King Of Games | #prototype-2 | 5 | |
| 89. | play play | Prototype2 Gameplay | 5 | |
| 90. | King Of Games | #prototype-2 | 5 | |
| 91. | King Of Games | Prototype 2 Прохождение Серия 2 | 5 | |
| 92. | King Of Games | Prototype 2 Прохождение Серия 7 | 4 | |
| 93. | sweetiegamig | Lets Play Prototype 2 Part 2 Der Ärger Geht Weiter | 3 | |
| 94. | King Of Games | #prototype-2 | 3 | |
| 95. | King Of Games | #prototype-2 | 3 | |
| 96. | King Of Games | #prototype-2 | 3 | |
| 97. | King Of Games | #prototype-2 | 2 | |
| 98. | King Of Games | #prototype-2 | 2 | |
| 99. | King Of Games | #prototype-2 | 2 | |
| 100. | King Of Games | Prototype 2 Прохождение Серия 3 | 2 | |
