| 2024-01-30 |  Falboyz Gaming | One of the best game ever | 3:22 | 4 |
| 2022-12-02 | TwigGames | Prototype 2 Multi Kill Cheat #respect #shorts | 0:31 | 1 |
| 2022-10-28 | Daveed | Easily one of the best games | 0:31 | 634 |
| 2022-07-11 | KillerWeirdo | Prototype 2 OST: A Labor of Love | 2:49 | 3 |
| 2022-01-24 | TwigGames | PROTOTYPE®2 | [GOD MODE] max upgrades (all abilities + skins) #prototype #respect #254 | 12:44 | 89 |
| 2022-01-24 | TwigGames | PROTOTYPE®2: Finale - Murder Your Maker (Final boss and Ending) #latest | 22:51 | 23 |
| 2022-01-21 | TwigGames | PROTOTYPE 2 PC Gameplay Walkthrough Part 1 FULL GAME [4K ULTRA HD] - No Commentary #latest | 15:06 | 63 |
| 2021-09-13 | BIGBadXO | let's play prototype on a playstation 2 | 0:29 | 242 |
| 2021-09-10 | SHAWKLAN 27 | PROTOTYPE 2 Ending: Mercer Vs Heller | 14:03 | 5 |
| 2021-07-21 | SHAWKLAN 27 | PROTOTYPE 2 James Heller is a peaceful boi | 0:30 | 2 |
| 2021-07-15 | SHAWKLAN 27 | PROTOTYPE 2 James Heller is a rude boi | 0:30 | 7 |
| 2021-07-07 | SHAWKLAN 27 | PROTOTYPE 2 Goliath Boss Fight | 3:47 | 11 |
| 2021-07-07 | SHAWKLAN 27 | PROTOTYPE 2 Looking for trouble? | 0:11 | 11 |
| 2021-07-05 | SHAWKLAN 27 | PROTOTYPE 2 NPCS Go poof | 0:30 | 13 |
| 2021-07-05 | SHAWKLAN 27 | PROTOTYPE 2 James Heller Black Moment | 0:15 | 13 |
| 2021-07-01 | SHAWKLAN 27 | [PROTOTYPE] Supreme Hunter Boss Fight and ending | 14:11 | 9 |
| 2021-06-28 | SHAWKLAN 27 | [PROTOTYPE] Elizabeth Greene Boss Fight | 17:48 | 5 |
| 2021-06-16 | SHAWKLAN 27 | PROTOTYPE 2 Ps5 gameplay | 45:39 | 9 |
