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| 2. | GeneralSecura | 36,403 | Let's Play Prototype #20 - Greene With Envy | 27:39 |
| 3. | ID Games | 33,459 | Wouters Speelkwartier - Prototype 2 | 7:54 |
| 4. | GameProsNL | 10,662 | Prototype 2 - Gameplay HD | 4:51 |
| 5. | Lone Wolf | 6,082 | Prototype 2 #88 Radnet Rewards Bonus Items and ALEX MERCER Skin | 5:21 |
| 6. | kmlkmljkl | 5,330 | hahahahaha! they're tearing you apart! | 0:08 |
| 7. | XGN | 5,007 | PROTOTYPE 2 - Review Trailer | 1:28 |
| 8. | LowkoTV | 1,169 | Prototype 2 PC Gameplay on MAX SETTINGS - With Commentary | 13:56 |
| 9. | How Big is the Map? | 688 | HOW BIG IS THE MAP in Prototype? Sprint Across the Map | 0:00 |
| 10. | k0noa | 509 | Prototype part 01: I FEEL LIKE A GOD! | 21:02 |
| 11. | techYOLOgie | 178 | Waarom je even moet wachten met het aanschaffen van een Playstation 4 | 3:51 |
| 12. | MegaDragonoid Gaming | 168 | Things to do in - ProtoType - Do you know me? | 7:34 |
| 13. | Blasti1987 | 109 | Protoype 2 Complete Playthrough Finale | 23:05 |
| 14. | JorRaptor | 92 | PlayStation Plus January 2015: Info About All The Free Games - Plusdate | 6:33 |
| 15. | Gamekings Vault | 69 | [GDC] Prototype | 4:16 |
| 16. | //Blank.05 | 22 | Prototype 2 diving highest building. | 0:25 |
| 17. | zarnok king of darkness | 16 | Talk about hogwart legacy while playing prototype 2 | 7:53 |
| 18. | Jarno & Shadowy | 14 | Prototype Playthrough - Part 4 - Guess what? Evolvement Blackwatch! | 56:14 |
| 19. | TheSubparGuys | 9 | Longplay - Prototype 2 | 6:22:45 |
| 20. | Paul-us | 6 | Steam | 2:37:32 |
