| 1. |  Julien Neel | I Got Rhythm (Gershwin) - A CAPPELLA barbershop quartet - Trudbol & JRoseJazz | 279,612 | |
| 2. | Julien Neel | Side By Side - Barbershop Quartet - Trudbol A Cappella | 234,552 | |
| 3. |  NPR Music | Takács Quartet: Tiny Desk Concert | 163,883 | |
| 4. | IceninjaX77 | Lost In Thoughts All Alone ~ Azura x Aqua x Shigure (EN) x Shigure (JP) [Quartet] | 115,610 | |
| 5. | NPR Music | Pacifica Quartet: NPR Music Tiny Desk Concert | 88,298 | |
| 6. | NPR Music | The Calidore String Quartet: NPR Music Tiny Desk Concert | 80,779 | |
| 7. | Triforce Quartet | Triforce Quartet: Themes from the Mario Bros Series | 80,309 | |
| 8. | NPR Music | Attacca Quartet: NPR Music Tiny Desk Concert | 76,941 | |
| 9. | ShinKimchi | ISEKAI QUARTET! EPISODE 1-10 LIVE REACTION + MUKBANG! BINGE WATCH! | 69,618 | |
| 10. | Songe | Super Mario Bros 2 - Overworld (Quartet Version) | 61,838 | |
| 11. | Songe | Sandy Badlands - Final Fantasy VII (Quartet Version) | 49,084 | |
| 12. | World of Longplays | Master System Longplay [067] Quartet - Double Target | 46,654 | |
| 13. | Chibi Reviews | Unexpected Friendship | Isekai Quartet Episode 3 | 45,059 | Review |
| 14. | Karin's Channel | Hatsune Miku: Project DIVA Future Tone - [PV] "Quartet of Multiple Futures" (Romaji/English Subs) | 38,334 | Let's Play |
| 15. | Foxen Anime | Which Is BEST Isekai Anime? Konosuba & ReZero RETURN! Isekai Quartet | Foxen Review | 35,606 | Review |
| 16. | Replay Burners | カルテット２ / Quartet 2 Loop1 part 1 of 4 | 23,600 | |
| 17. | [ SUMiKA ] Saxophone | 【Sax Quartet】唱 / Ado【サックス四重奏】Saxophone Quartet | 21,158 | |
| 18. | PocketMonstersMusic | Pokémon Anime Song - Smile (Piano & String Quartet Version) | 20,451 | |
| 19. |  G.O.T Games | First Time Reacting to "ISEKAI QUARTET 2 Openings & Endings (1-2)" | New Anime Fan! | 19,812 | |
| 20. | Talks at Google | Lunchtime Concert | The Dover Quartet | Talks at Google | 16,324 | |
| 21. | My Life in Gaming | Quartet - Arcade VS. Master System / MY LIFE IN GAMING | 14,802 | |
| 22. | Axolity | Kayna, Persicorp, Rootitoot, Oaktapus (Quartet) MSM Psychic Island | 13,840 | |
| 23. |  spm moto | ダブルターゲット シンシアの眠り（SEGA MARKⅢ） クリア動画 | 13,739 | |
| 24. | Jeremy Parish | Video Works | Console conversions, paired down: Shooting Gallery & Quartet | Segaiden #042 | 13,223 | Show |
| 25. | Mimi | Space Hamster Quartet - Mobile Coffin memes #27 | 12,315 | |
| 26. | LumineNd | Ben Johnston – String Quartet No. 10 (1995) | 12,248 | |
| 27. |  Janet의 고전게임오락실 | 1/5 Quartet(SEGA) - 1CC | 12,032 | |
| 28. |  Shelos1Life | KONOSUBA + OVERLORD + RE:ZERO + TANYA - Isekai Quartet #1 | 11,492 | |
| 29. | medici.tv | Modigliani Quartet - String Quartet No. 12 in F Major "American" - Dvořák | 11,249 | |
| 30. |  This Channel Is Being Deleted on May 21st | Isekai Quartet S1 E1 - "Come Together! Quartet" & E2 - "Tension! Introductions" Reaction | 10,748 | |
| 31. | TrackerTD | GETREADY - #2 - Tajuu Mirai No Quartet (Quartet Theme) ft. Hatsune Miku | 10,440 | |
| 32. | Shelos1Life | TANYA VS AQUA (YOUJO SENKI VS KONOSUBA) - Isekai Quartet #9 | 10,274 | |
| 33. |  Stam Fine | Fantastic Four. The Flawsome Foursome in a Questionable Quartet. | 10,181 | |
| 34. | Shelos1Life | KAZUMA VS REINHARD (KONOSUBA VS RE:ZERO) - Isekai Quartet #11 | 9,323 | |
| 35. |  quartetotessares | Shadow of the Colossus - A Violent Encounter - Tessares String Quartet (Quarteto Tessares) | 8,637 | |
| 36. |  Ramdadi | Asyik ! Boboiboy galaxy Card Game Quartet melawan musuh luar angkasa | 8,340 | |
| 37. | Media Pool | 1986 Quartet (Arcade) Game Playthrough Video Game | 8,294 | Let's Play |
| 38. | Michirin | 【SEGA】Quartet - Stage 1 - PC engine Cover Rearranged 【Deflemask】 | 8,279 | |
| 39. | Shad G | SEGA-con - Quartet - Quartet Theme (Screen 1 BGM) | 8,233 | |
| 40. | OverClocked ReMix: Video Game Music Community | OC ReMix #2114: Final Fantasy IV 'Edward's Dream Quartet' [Edward's Harp] by Abadoss & James George | 8,121 | |
| 41. | OxfordSong | Schumann Quartet No.1 - The Doric Quartet - Oxford Lieder Festival 2015 | 7,828 | |
| 42. | KianMSM | Larvaluss, Xyster, Deja-Jin, and Roarick quartet (Magical Sanctum) | 7,717 | |
| 43. | Shelos1Life | TANYA VS KAZUMA (YOUJO SENKI VS KONOSUBA) - Isekai Quartet #10 | 7,238 | |
| 44. | Shelos1Life | AINS VS SUBARU (OVERLORD VS RE:ZERO) - Isekai Quartet #7 | 6,801 | |
| 45. | SEGA Retro BR | Quartet / Double Target: O quarteto que virou dupla! | 6,797 | |
| 46. | purpleschala | Opening - Bombing Mission - Final Fantasy VII (for piano + string quartet) | 6,452 | |
| 47. | medici.tv | Takács Quartet - String Quartet No. 13 (II. Presto) - Beethoven | 6,439 | |
| 48. | KianMSM | Frondley, G'Day, Fluoress, and Mushaboom quartet (Magical Sanctum) | 6,308 | |
| 49. | Triforce Quartet | 05 - Triforce Quartet - Secret of Mana - Main Theme | 5,749 | |
| 50. | Mimi | Space Hamster Quartet - Bottle Mix Memes #31 | 5,689 | |
| 51. | Shelos1Life | Ainz VS Emilia (OVERLORD VS RE:ZERO) - Isekai Quartet #6 | 5,665 | |
| 52. | SEGA Retro BR | Quartet: O quarteto fantástico da SEGA! | 5,525 | |
| 53. | medici.tv | The Arod Quartet - Schumann, String Quartet No. 1 | 5,480 | |
| 54. | 洗足学園音楽大学/SENZOKU GAKUEN college of Music | SMC 『Tomonao Hara Quartet LIVE！』 | 5,440 | |
| 55. | Mimi | Space Hamster Quartet #1 | 5,275 | |
| 56. | Replay Burners | カルテット２ / Quartet 2 Loop1 part 2 of 4 | 5,266 | |
| 57. | pokedude900 | Isekai Quartet Adventure:Action Game Stage 1 | 5,161 | |
| 58. | Mimi | Space Hamster Quartet #26 | 5,095 | |
| 59. |  Staszek iGRAszkowski | Quartet PL 💬 #1 | Klasyczne jRPG z klimatem czasów pierwszych Final Fantasy! | 5,064 | |
| 60. | OverClocked ReMix: Video Game Music Community | Echoes of Betrayal, Light of Redemption: 1-13 Edward's Dream Quartet (Final Fantasy IV / OC ReMix) | 5,020 | |
| 61. | medici.tv | Master class: Takács Quartet - Wigmore Hall: Beethoven, String Quartet No. 7 "Razumovsky" | 4,989 | |
| 62. | TrackerTD | GETREADY - #3 - FM Funk (We Love SEGA Mix) (Quartet) ft. Megurine Luka | 4,622 | |
| 63. | medici.tv | The Emerson Quartet farewell concert #Shorts #Quartet #EmersonQuartet | 4,585 | |
| 64. | Triforce Quartet | Triforce Quartet: Mario Galaxy - Gusty Garden, & Mario World - Ending | 4,461 | |
| 65. | Replay Burners | カルテット２ / Quartet 2 Loop1 part 4 of 4 | 4,175 | |
| 66. | medici.tv | The Modigliani Quartet with Agnès Letestu and Florent Melac - Ravel: String Quartet | 4,012 | |
| 67. | Just the Gems | This Indie JRPG Does Almost EVERYTHING Right | Quartet Review | 3,857 | |
| 68. |  Anime man Tv2 | ISEKAI QUARTET Re Zero Subaru Natsuki 😈 #isekaiquartet #subarunatsuki #rezero | 3,761 | |
| 69. | TJ DW | Hellraiser: Bloodline 4K UHD Blu-ray VS Blu-ray Comparison | Hellraiser Quartet Of Torment 4K | 3,746 | |
| 70. | My Life in Gaming | Monster in my Pocekt (NES) & Quartet (Sega Master System) Couch Co-op :: LIVE STREAM | 3,730 | |
| 71. | Mimi | Space Hamster Quartet - Bottle Memes #30 | 3,633 | |
| 72. | TheMisterYuTube | KRONOS QUARTET - Dracula 1931 soundtrack - fan made Music Video - BELA LUGOSI | 3,565 | |
| 73. | torikusai | 弦楽四重奏曲モノポリー 楽しく行こう String Quartet The Monopoly - Let’s Have Fun | 3,492 | |
| 74. | SEGA Retro BR | Detonado: Quartet / Double Target (Master System) | 3,363 | |
| 75. | translation | [BGM] [AC] カルテット [Quartet] | 3,322 | |
| 76. | Pixel Party Pals | Every Easter Egg in Isekai Quartet Part 2! REACTION | 3,124 | |
| 77. | Retro Hawk | Quartet - Arcade Gameplay - SEGA 1986 | 3,121 | |
| 78. | Mimi | Space Hamster Quartet #33 | 3,104 | |
| 79. | torikusai | 弦楽四重奏曲モノポリー モノポリーへの招待状 String Quartet The Monopoly - The Invitation to Monopoly | 3,001 | |
| 80. | medici.tv | 1st Grand Prix of the Bordeaux International String Quartet Competition: Leonkoro Quartet | 2,973 | |
| 81. |  Blossom AMV 菜 | Yozakura Quartet【AMV】Hollywood Perfect ᴴᴰ | 2,961 | |
| 82. | MAGFest | MAGFest 2019: Triforce Quartet | 2,944 | |
| 83. | Quattro String Quartet | Birds of a Feather - Billie Eilish - String Quartet Cover - Quattro String Quartet | 2,893 | |
| 84. | Kaeru-kun's Retorogaming Channel | 【セガマークIII】ダブルターゲット 2人同時プレイでノーミスクリア【レトロゲームゆっくり実況】 | 2,834 | |
| 85. | torikusai | 弦楽四重奏曲モノポリー 街並みを行く String Quartet The Monopoly - The Street Adventure | 2,804 | |
| 86. | Replay Burners | カルテット２ / Quartet 2 Loop1 part 3 of 4 | 2,752 | |
| 87. | LowBrassLuke | Quartet is a fantastic new Play-Along App. Check it out in the Apple App Store. #quartet #app | 2,661 | |
| 88. | medici.tv | Rolston String Quartet - String Quartet No. 8 - Beethoven: 12th BISQC (Finale) | 2,470 | |
| 89. | medici.tv | Castalian String Quartet - String Quartet 14, "Death and the Maiden" - Schubert: 12th BISQC (Finale) | 2,439 | |
| 90. |  AH Brandon Reviews | Best Re:Zero Moment Is Now the Best Quartet Moment | Isekai Quartet Season 2 Episode 10 (22) Review | 2,412 | Show |
| 91. | orbalology | First Impressions of the Turn-Based Indie JRPG Quartet LIVE! | 2,398 | |
| 92. | LivTheCyberDhole | Nozz Watches Isekai Quartet Season 2 [Episode 4] | 2,373 | Show |
| 93. | PugmanPlays | Quartet Arcade CO-OP (2 player) Complete playthrough. Up to level 75 (longplay) HD - (part 1) | 2,351 | Let's Play |
| 94. |  ARD Klassik | Childs - Streichquartett Nr. 3 Unrequited I Isidore String Quartet | 2,283 | |
| 95. | Mimi | Space Hamster Quartet - Star wars - memes | 2,228 | |
| 96. | RA 2 | Quartet Review For Sega Master System | 2,140 | Review |
| 97. | JustDaZack | QUARTET – Unique 8 Party-Members Fantasy JRPG | 2,104 | Review |
| 98. | AH Brandon Reviews | Overlord Season 4 Release Date & Isekai Quartet Movie Update! | 2,103 | |
| 99. | TASVideosChannel | [TAS] Arcade Quartet "1 player" by Darkman425 in 22:48.55 | 2,040 | |
| 100. | LivTheCyberDhole | Nozz Watches Isekai Quartet Season 2 [Episode 1] | 2,032 | Show |
