| 2024-06-17 |  Orion Blair Phoenix Gaming | 165 | SERENA FULL INDIE GAME | 1:07:25 |
| 2022-09-14 |  Edgley Games | 6,010 | E's Laf - Gameplay with Serena (PC) [Playthrough/LongPlay] | 14:58 |
| 2022-03-28 |  RAITSI | 2,000 | kabur dari sekolah hantu - dimensi lain serena - game horor indonesia | let's Play Gameplay | 18:23 |
| 2022-01-18 | Ragekitt | 595 | This Redditor did WHAT to his wife?! [Serena Playthrough] | 39:27 |
| 2021-07-06 |  TheLousyLoser | 223 | Unterwegs in Düsterburg | #29: Katzengasse Nr. 5 | PC | Let's Play | 32:46 |
| 2020-10-06 |  Keith Ballard | 136,000 | Let's Play Serena - Do I Deserve to Be Forgiven? | 59:28 |
| 2020-06-24 | The RPG Chick | 8,800 | Let's Play Asylum (Demo - Blind), Part 1 of 4: Return to Hanwell Institute | 30:52 |
| 2020-05-25 | SqUiShY Gaming | 17 | Lost And Confused | Let's Play Serena | 22:43 |
| 2020-03-20 | theRCLman | 29,200 | 🕵️We're Little DETECTIVES!!!🕵️ | Kika & Daigo A Curious Tale Let's Play (w/ Serena) | 32:11 |
| 2019-08-10 |  Cam | 477 | Cam Plays: Prom Dreams | Part 8 | The Forger's Hand Ending | 55:19 |
| 2019-05-30 | wolfcub46 | 59 | Wolf Plays - Serena [Final] | 33:45 |
| 2019-01-06 |  Jeajax | 806 | Let's play! Serena | 51:12 |
| 2018-12-12 | The Bigender Gamer | 610 | SERENA | Alex Replays | 40:41 |
| 2018-06-21 |  Avenclave | 194 | Let's Play SERENA #4 - Was für eine Tragödie! [Deutsch/German] | 18:44 |
| 2018-01-01 |  Hybridjunkie | 46,200 | Let's Play - Serena | 43:47 |
| 2017-10-09 | Aul In | 15,100 | Serena - Full Play Through | 1:02:47 |
| 2017-09-01 |  SilverDarkPhoenix | 221 | Serena - Playthrough ( Please Shoot Me In The Head ) | 51:29 |
| 2017-07-26 |  CorrosiveLick | 52 | Where did she go | Serena | CorrosiveLick Let's Play! | 21:18 |
| 2017-05-04 | iimjoeyy | 492 | SERENA FullPlaythrough! WHERE IS SERENA?! | iimjoeyy | 32:28 |
| 2017-02-11 |  Gold Styles (Goldstyles) | 50 | Serena - FINALE - Let's Play - Capitolo 3 | 26:48 |
| 2016-12-16 | Nessas Gamingzone | 9,900 | Plot-Twist! | Nessa spielt SERENA [Full Game] [Facecam, HD+] | 1:06:00 |
| 2016-10-01 | MoonlitWenny | 1,320 | OH MY GOD | Let's Play Serena | 42:41 |
| 2016-09-02 |  Tr1pw1re | 414 | The Truth Revealed! | Serena (PC) - Part 2 [End] | 23:50 |
| 2016-06-23 | Euclid | 4,040 | Let's Play Serena. Am I going crazy!? | 53:32 |
| 2016-02-18 | EmptyGarbageCan | 7,270 | Serena | 28:34 |
| 2016-01-25 | Rostbrot | 366 | Der Schrank | Let's Play Serena [German/Deutsch] #3 | 12:01 |
| 2016-01-20 | Nick Munger | 314 | Let's Play Serena | MESSED. UP. STUFF. | 32:14 |
| 2015-12-11 | Radedo | 488 | AM I GOING CRAZY TOO? - Let's Play Serena Full Gameplay | 1:20:51 |
| 2015-12-06 | Spunkster | 84 | Serena - THE FEELS IS STRONG! - Full Playthrough | 34:55 |
| 2015-10-21 |  ScarabD | 254 | Scarab plays: Serena [003-END] - The Armoire | 22:49 |
| 2015-10-07 | tacoline | 599 | Let's Play Serena pt 2 Fiery end | 28:11 |
| 2015-10-04 | Monmia | 192 | Let's Play an Indie Horror!_Serena [#2] | 17:28 |
| 2015-10-04 | Emargy LPT | 82 | Let's Play Serena Part 02 - Enthüllungen - Finale | 29:12 |
| 2015-08-27 | ThrashingBunny | 35 | Serena let's play (full game) | 54:01 |
| 2015-05-17 | Kraken | 14,400 | lets play serena click point adventure indie | 16:45 |
| 2015-03-30 |  LanokirX | 26,300 | Serena | Full Playthrough | 35:37 |
| 2015-02-17 | JAC OneManBand | 18,000 | Cabin In The Woods: JAC Plays: Serena | 50:29 |
| 2015-01-31 | TheIntendantS | 20 | Intendant S Plays Serena | 1:08:41 |
| 2015-01-31 | MartinSpielt | 79,500 | Serena - Let's Play - Teil 2/2 | 48:54 |
| 2014-09-22 | PoetryStud | 4,930 | Lets Play Serena - Indie Point and Click Game [#1] | 9:17 |
| 2014-06-25 | YagmanX | 56,300 | Wimpy Girl Plays Serena | That Ending?! | 23:38 |
| 2014-05-26 | bradye21 plays... | 672 | Let's Play Serena -3- Theres only one way anything can end (Finale) | 9:08 |
| 2014-05-20 | nekobun | 503 | Serena - Full Playthrough | 1:19:57 |
| 2014-04-25 | IceAngelQueen | 195 | Ice Plays: Serena - Part 1 | 25:31 |
| 2014-04-22 | Slail | 1,180 | Let's Play Serena - A One Part LP | 50:19 |
| 2014-03-17 | Vinithian | 546 | Let's Play Serena Part 5 | 12:32 |
| 2014-03-08 | UbuntuGamingProject | 721 | Let's Play on Ubuntu: Serena (Steam) | 11:11 |
| 2014-02-22 | 006Cronos | 784 | Let's Play: Serena (Part 2) | 16:33 |
| 2014-02-15 | Max Blackwing | 13,600 | Lets Play Serena: #To Spooky For Me!!~ | 53:20 |
| 2014-02-12 | Fussball mit Heel Phakdi | 236 | Serena Let's Play #005 - The End![HD+][Deutsch] | 10:57 |
| 2014-02-09 | CraigieG | 693 | Serena - Episode 2 - I finally understand....? | 16:39 |
| 2014-02-08 | NoAgendaStudios | 1,590 | Let's Play Serena | 1:07:04 |
| 2014-02-08 | Zalzar | 394,000 | Serena | IT BROKE MY HEART... | Gameplay Playthrough w/ facecam | 37:10 |
| 2014-02-07 | Elenkoism | 254 | Serena | Part 4 | Shocking Revelation | 12:40 |
| 2014-02-04 | ZokkerBunny Jey | 1,320 | SERENA #02 | Die Wahrheit kommt ans Licht ҳ̸Ҳ̸ҳ Let's Play Serena | 49:19 |
| 2014-02-04 | l0stw0lf | 1,520 | Serena - Free Creepy Indie Point & Click Narrative - Part (3/3) FINAL - l0stw0lf plays | 16:42 |
| 2014-02-03 | EchoLP | 610 | Angespielt | Serena [Part 3/3] - "Nur benutzt...?" | Let's Play Serena | German | HD | 22:11 |
| 2014-02-01 | spudheds | 863 | Spudheds Plays - Serena - Full playthrough | 41:09 |
| 2014-01-30 | Shook50 | 394 | Let's Play Serena (Suspensful, Spooky Point and Click Adventure) | 39:10 |
| 2014-01-30 | God is a Geek | 22,300 | Serena - Let's Play | 10:23 |
