| 2024-04-26 |  Jareth Let ́s Play | 1,520 | Let's Play Serious Sam HD: TSE #021 [Deutsch] [UHD] - Ausgezaubert! [Finale] | 28:29 |
| 2024-04-16 |  Dr. Atecep | 4,080 | SERIOUS SAM HD: THE SECOND ENCOUNTER #5 | Playthrough PT-ENG | 2:00:30 |
| 2024-04-07 |  Vault of console games | 680 | Serious Sam: The Second Encounter |4k60fps| Longplay (Xbox Original) | 6:12:15 |
| 2024-04-05 | Serious Santa | 184 | Serious Sam: Alpha [Remake] | Прохождение | #2 | 22:00 |
| 2024-01-11 | Longplay Studio 313 | 2,410 | Serious Sam HD: The Second Encounter - Legend of the Beast Longplay (Playstation 4) | 2:37:46 |
| 2024-01-01 | BIG TONY | 392 | Serious Sam The Second Encounter HD|60fps 1080p Ps4|Playthrough Part 12 | 59:11 |
| 2023-10-03 |  RatchetGamingAllStars | 906 | Ps4 Serious Sam The Second Encounter Gameplay Playthrough | 5:10:00 |
| 2023-08-24 | Meti Walkthroughs | 640 | Serious Sam The Second Encounter - SpeedLevel - Incomplete Playthrough | 10:22 |
| 2023-07-27 |  Gouludword | 10,800 | นับ 1-5 Playstation เรื่องราวของคอนโซลอันดับหนึ่ง / Playstation 2 | 0:58 |
| 2023-07-19 | NecroManZer | 51 | Пара слов о Serious sam Alpha | 6:36 |
| 2023-04-22 | Cheddar Shadooby | 31 | Red faction PlayStation 4 | 34:31 |
| 2023-04-05 | Viktor Games | 338 | СВЯЩЕННЫЙ ДИСБАЛАНС | Serious Sam: Hell Encounter Impossible+++ | #3 | 1:16:46 |
| 2023-03-04 |  SuperSaiyanDragon | 58 | Serious Sam HD: The Second Encounter Episode XII Gameplay playthrough (No Commentary) The Cathedral | 57:12 |
| 2023-02-11 |  WinXP_SP1 | 1,270 | ReactOS running Serious Sam Alpha and Half-Life | 6:04 |
| 2023-01-26 |  MPlayGaming | 1,340 | Serious Sam HD: The Second Encounter Playthrough The Grand Cathedral [4/5] 4K UHD | 7:57 |
| 2022-12-18 |  Serious Mkbewe | 1,510 | Serious Sam The Second Encounter - Alpha Reimagined and Future Enemy Resource Pack | 1:08:35 |
| 2022-11-02 | EWA Gamesroom | 486 | Faz Plays - Serious Sam HD: The Second Encounter (Xbox 360)(Gameplay) | 21:34 |
| 2022-09-11 |  CloudCrafts | 29,100 | Serious Sam HD: The Second Encounter Playthrough (Part 2) Palenque - Sierra de Chiapas [1/3] | 14:15 |
| 2022-06-14 |  GameVersum | 248 | Serious Sam HD The Second Encounter Complete Gameplay PART 15 - The Lava Caves (2K 60FPS) | 33:43 |
| 2022-04-09 | mkssa | 9 | Let's play! #1 Serious Sam: The Second Encounter (2-ая серия) | 26:55 |
| 2022-04-03 |  KHGhost | 1,970 | Serious Sam's World War 3 (Ending) | Serious Sam The Second Encounter HD Blind Playthrough | PS5 | 1:47:04 |
| 2022-03-30 | EpixKev04 | 136 | DAS EPISCHE FINALE!!! (FINALE) | Serious Sam TSE Classic #20 | LetsPlayTogether SonKi84 + EpixKev04 | 27:08 |
| 2022-03-29 | Rob Flynn (Wolverous) | 1,440 | Serious Sam: The Second Encounter | 5:00:41 |
| 2021-12-18 | EON | 845 | Serious Sam (The First and Second Encounter) Maximum Speed & Fire Rate | Full Gameplay | part 6 | 38:49 |
| 2021-12-17 | DarkRaptor86 | 239 | Lets Play Together Serious Sam: The Second Encounter Classic Edition Folge 24 | 27:01 |
| 2021-07-28 |  Polignano a Meme | 13,800 | Polignano a Meme plays Serious Sam: The Second Encounter | 37:07 |
| 2021-07-08 |  Freeman Bg - TV | 2,220 | Serious Sam on Ps Vita 😈 Serius Dungeons PSP Homebrew 🛠️ | 13:49 |
| 2021-04-21 | KING MORGAN | 3,270 | Tyrone plays Serious Sam the Second Encounter More Serious Levels | 1:15:02 |
| 2020-12-12 | GunslingerSyayo | 236 | Let's Play & Finish Serious Sam 2nd Encounter Before SS4!! #7 | 21:28 |
| 2020-10-04 |  VISUAL NOVEL GATE | 2,190 | MARCH OF THE DEAD - Gameplay | 10:18 |
| 2020-09-21 | VampirchickenLP | 1,280 | Lets Play Together Serious Sam: Second Encounter (blind) #35 - Mordekai, der Beschwörer | 21:05 |
| 2020-08-28 | FramePlay | 4,720 | Serious Sam 2000 Alpha Build | Unfinished Levels (ROUGH FOOTAGE) | 59:49 |
| 2020-05-30 | GuyNamedErick | 2,810 | Serious Sam: The Second Encounter - Serious Playthrough - All Secrets | 5:51:08 |
| 2020-04-30 | PS2freak11223 | 309 | Let's Play Serious Sam HD 2: Serious Sam and the Temple of the Crystal Indiana Jones Harpy | 17:18 |
| 2019-08-03 | GermanGamers2000 | 161 | [Single] Let's Play: Serious Sam: The Second Encounter HD PART 01 | 15:01 |
| 2019-06-19 |  LetsPlayOnePiece | 533 | Let's Play Serious Sam HD: The Second Encounter [Ende] #033 - Das legendäre Biest | 36:39 |
| 2019-04-29 |  KE1nonen | 11,300 | Serious Sam: The Second Encounter - Alpine Mists II: Dusts of Ages Part 2 (Serious) | 52:29 |
| 2019-03-19 | The Royal Guard | 1,070 | TheRoyalGuard | Serious Sam HD: The Second Encounter | Playthrough | 1080p 60fps | 59:00 |
| 2018-09-04 | Neon Henchman | 242 | Serious Sam: LPR: Démente [17] Pyramide en bois | 30:15 |
| 2018-08-22 | CHAOS ROOKIE | 133 | Serious Sam (Xbox) Let's Play part 34 The final battle | 23:40 |
| 2018-05-25 | McPhisto2051 | 43 | #24 - Serious Sam - The Second Encounter (LP/1080p/60fps/ger) - The Grand Obelisk 2/2 | 24:25 |
| 2018-04-16 | Sephiroth Let's Play | 1,090 | SERIOUS SAM HD: THE SECOND ENCOUNTER #08 - Into the Storm! - Let's Play Together | 18:36 |
| 2018-02-18 | Wickman Wish | 18,200 | Let's Play Serious Sam HD: The Second Encounter [Co-op] - Part 16 | 26:43 |
| 2017-08-18 | Zarbach | 664 | Let's Play Serious Sam The Second Encounter HD | FINALE | Deutsch [Teil 50] | 15:37 |
| 2017-08-08 | Snack Time Sports | 837 | Let's Play Serious Sam: The Second Encounter [Co-op] - Episode 10 (Finale) | 37:49 |
| 2017-02-05 | SlyfoXlive | 2,050 | Let's Play Serious Sam The Second Encounter HD Co-op mit DickWanst & SlyfoX | 21.01.2017 | #15 | 50:28 |
| 2016-12-17 | WhamNinjaMolehill | 5,730 | Live Stream: Serious Sam HD: The Second Encounter Blind Playthrough - Part 3 | 4:18:06 |
| 2016-12-12 | Van FirleFranz | 625 | Serious Sam The Second Encounter # 26 noch mal alles drauf FINALE Let's Play German, Deutsch | 16:26 |
| 2016-12-11 |  Muppio | 960 | Let's Play Serious Sam HD: The Second Encounter - 1 - Sierra de Chiappas | 27:02 |
| 2016-10-07 | Trientia | 639 | Let's Play Serious Sam HD The Second Encounter Episode 4: Serious Courtyard | 18:11 |
| 2016-07-18 | AveBatTV | 5,000 | Serious Sam HD The Second Encounter coop part 13 Last Boss END | 2:56 |
| 2016-05-20 | Valdis348 | 6,280 | Valdis vs. SpinatpiZZa (1.11) : Serious Sam: 2nd Encounter | 24:23 |
| 2016-05-17 |  TheMasters PS | 884 | Serious Sam SECOND Encounter HD COOP / Mr Meep | EP15 | 18:45 |
| 2016-02-13 |  TOMMYK Yt | 544 | CZ let's play Serious Sam The firts encounter #13 FINAL | 36:53 |
| 2015-08-14 |  Magicolo - Free Games | 31,600 | Serious Sam ALPHA Remake - Mod 2015 | 3:08 |
| 2015-05-29 | Jironobou | 120 | Let's Play Serious Sam ╘66═ Raining Hell | 18:47 |
| 2015-04-17 | Simpelicity | 2,100 | Let's play Serious Sam SE [29] Lift off | 27:16 |
| 2015-04-10 | Natiunea Jucatoare | 1,040 | [RO] Let's Play Serious Sam the Second Encounter - Part 14 - ULTIMUL EPISOD | 29:47 |
| 2014-12-15 | TeeZaah | 122 | Let's Play Serious Sam (TSE) Part 2 - SPIKY ROOM | 20:15 |
| 2014-12-01 | MissFortunaLP | 2,290 | Let's Play Serious Sam: The Second Encounter [feat. Sunfact & NoXxX] (Deutsch/German/Blind) #10 | 29:49 |
| 2014-09-13 | Serious Sacor | 3,460 | Serious Sam: The Second Encounter Playthrough (Commentary) - Part 31 - The Grand Cathedral (4/4) | 17:51 |
| 2014-08-25 | nixan | 879 | [let's play] Serious Sam (german) part 21 | 26:09 |
| 2014-04-14 |  Gar | 23,400 | Serious Sam HD: The Second Encounter Legend of the Beast (Commentary) Part 4: Legendary Beast | 39:16 |
| 2014-02-02 | Arm4g3dd0nX | 15,200 | Let's Play: Serious Sam Second Encounter (P3) | 32:33 |
| 2013-12-11 | 7 Different Kinds Of Smoke | 1,080 | Rus Lets Plays by M@x512 BLR : Уровень Бонус v 1 1 | 25:20 |
| 2013-10-11 | flaschorLP | 31,100 | SERIOUS SAM HD: THE SECOND ENCOUNTER [07] - Serious Seriousness | Let's Play Together | 26:00 |
| 2013-09-30 | Popular Geekery | 553 | The Popular Geekery crew plays Serious Sam TSE pt2 | 23:38 |
| 2013-06-16 | chk brk | 11,400 | Get Serious! Serious Sam The Second Encounter Part 4 | 5:35 |
| 2013-01-09 | GermansnakeGaming | 150,000 | Serious Sam HD The Second Encounter Deutsch (Coop) #001 - Serious Sam ist zurück! | 14:58 |
| 2012-11-23 | Andrea Rovenski | 11,500 | Serious Sam: The Second Encounter CO-OP Playthrough; Part 7 | 27:44 |
| 2012-08-06 | Stromsky | SkyCat | 958 | LPT Serious Sam 1 First Encounter #007 [Nikk] "The Ring" | 13:28 |
| 2012-05-18 | NeoTyrant | 390 | Serious sam - Legend of the beast DLC coop playthrough part 5 | 18:12 |
| 2012-03-09 | kilplixism | 69,300 | Kilplix N Tate Play Serious Sam The 2nd Encounter #2 | 20:07 |
| 2011-06-06 | Ikarru | 60 | Let's Play Serious Sam Second Encounter Part 1 | 41:02 |
| 2011-03-22 | Loki D.S. | 20,500 | Serious Path - Alpha | 1:32 |
| 2009-10-10 | Juliean | 460 | Let's play Serious Sam Part 6 - der erste Goldjaguar | 9:46 |
