| 1. |  BlobVanDam | 2,650,988 | Sonic & Knuckles 3D - Mushroom Hill Zone | 0:47 |
| 2. | Michael McKenzie | 55,417 | Sonic 3 & Knuckles - Sandopolis (Sonic) speedrun tutorial | 29:29 |
| 3. | Adrian Gauna | 33,930 | The Doomsday - Sonic & Knuckles SEGA Mega Drive | 3:44 |
| 4. | Saxdude26 | 29,899 | Sonic & Knuckles - Death Egg Zone [PITCHED DOWN Mix] | 3:57 |
| 5. | Werster | 26,829 | Sonic 3 & Knuckles - Sandopolis 2 Glitchless Knuckles: 2:10 (Speed Run) | 2:30 |
| 6. | The Consouls | 26,127 | Mushroom Hill (Sonic & Knuckles) Funk Cover - The Consouls | 3:58 |
| 7. | Infinite The Jackal | 17,617 | Infinite, Metal Sonic & Knuckles Play Bed Wars - Part 2 | 21:06 |
| 8. | OniLink99999 | 17,027 | Sonic & Knuckles Mega Drive (Genesis) Unboxing | 11:02 |
| 9. | ColourShedProductions | 12,054 | Sonic & Knuckles review - ColourShed | 7:46 |
| 10. | Anubis_editzz | 4,922 | Shadow humbled Sonic and Knuckles | Odetari - Keep up | 0:00 |
| 11. | Retro Longplays | 4,746 | PS2 Longplay - Sonic and Knuckles from Sonic Mega Collection Plus - Played as Knuckles (PAL Version) | 54:30 |
| 12. | Cypher Mighty | 3,192 | Sonic Vs Knuckles | #sonicthehedgehog #versus #viral #shorts | 0:25 |
| 13. | Rabbit OST | 1,657 | Sonic 3 & Knuckles OST 'Invincible (Sonic & Knuckles)' | 0:35 |
| 14. | The World-Plex - Basketball Action | 1,306 | Sonic the Hedgehog Sonic & Knuckles #sega #sonicandknuckles #sonicthehedgehog | 0:00 |
| 15. | dshaynie | 667 | Super Classic sonic Livestream #3 & Knuckles | 3:00:23 |
| 16. | giga6152 | 636 | Sonic and Knuckles Fight (Macromedia Flash 8 Test) | 0:19 |
| 17. | ~ Rhapsody2612 ~ | 596 | Sonic & Knuckles/Sonic Mania - Lava Reef Zone Bad Future | 1:58 |
| 18. | Alex Field (OLD CHANNEL) | 388 | "Giant Floating Cylinder" | Sonic & Knuckles Collection - Part 2 | 0:00 |
| 19. | GameBoyJR | 252 | Sonic & Knuckles & Sonic 1 | 0:37 |
| 20. | Itsyaboydan | 248 | Sonic & Knuckles Collection - Original Game Soundtrack | 0:00 |
| 21. | Solidus-Skully | 234 | Sonic and Knuckles Commentary Part 6 Prophecy (FINAL) | 25:26 |
| 22. | dumbdickeez | 223 | Sonic & Knuckles SUPERCUT - dumbdickeez | 7:42 |
| 23. | J.Russell Retro Gaming | 206 | Sonic & Knuckles - Sega MegaDrive II + YPbPr Output - PAL | 2:03:00 |
| 24. | TotessMagotess | 187 | The Hidden Palace | Sonic the Hedgehog 3 & Knuckles | Part 5 | 22:58 |
| 25. | Cypher | 183 | Movie sonic and knuckles share some similarities edit #edit #videogameedit #sonicvsknuckles | 0:15 |
| 26. | Zenuith Productions | 129 | Sonic and Knuckles play Would You Rather? (Ft. MUI Knucklespuncher77) | 28:31 |
| 27. | reclusebass\Mcollective | 119 | Mushroom Hill Zone Act 1 | Sonic & Knuckles Bass Playthrough (interpretation) | 2:37 |
| 28. | Bobby Peters | 99 | WTF IS THIS!!?? Knuckles Mania and Knuckles | Sonic Mania Mods | 15:57 |
| 29. | LittleBigPlanet CoMmunity Level Footage Library | 92 | Sonic & Knuckles: Death Egg Zone Boss by lukex34 - LittleBigPlanet | 6:39 |
| 30. | SuperSaiyanSonic | 77 | & KNUCKLES | Sonic Mania Part 4 - FLYING BATTERY ZONE | 14:14 |
| 31. | lsaacTV | 61 | How to get Sonic and Knuckles! *Full Guide* Sonic Speed Simulator! | 5:56 |
| 32. | MysticalMachineGun | 31 | Sonic 3 & Knuckles - Pt. 4 - Knuckles 2 | 0:00 |
| 33. | taximals (VoD Archive) | 23 | [VoD][AUS VTUBER] Sonic & Knuckles [Full Playthrough!] | 3:53:28 |
| 34. | Stephen Berg | 8 | Sonic and Knuckles - Sega Mega Drive / Genesis | 6:05 |
| 35. | JadellsBB | 4 | N O S T A L G I A !! - Sonic & Knuckles and Zoo Tycoon | 48:26 |
