| 1. |  RetroGame.Stream | Sonic & Knuckles - Sega Genesis - Full Sonic Playthrough No Commentary | 1,156 | Let's Play |
| 2. | Cybershell | Let's Play Sonic 3 & Knuckles: The Doomsday Zone | 581 | Let's Play |
| 3. |  Chronicle2H | Sonic 3 and Knuckles Playthrough: Super Mecha Sonic (Knuckles) | 566 | Let's Play |
| 4. | Cybershell | Let's Play Sonic 3 & Knuckles: Hidden Palace Zone | 248 | Let's Play |
| 5. | LankyBox | BEST SONIC VIDEOS EVER! (SONIC.EXE VS ALPHABET LORE, SCARY 3AM SONIC MOVIE, SONIC OBBY, & MORE!) | 190 | Let's Play |
| 6. | Cybershell | Let's Play Sonic 3 & Knuckles: Flying Battery Zone (Part 2) | 181 | Let's Play |
| 7. | Retro Master | Sonic The Hedgehog 3 & Knuckles Playthrough (Part 2) | 178 | Let's Play |
| 8. |  FramePlay | Sonic 3 & Knuckles PC: 100% Playthrough + Knuckles Gameplay | 166 | Let's Play |
| 9. | Cybershell | Let's Play Sonic 3 & Knuckles: Mushroom Hill Zone (Part 1) | 161 | Let's Play |
| 10. | Cybershell | Let's Play Sonic 3 & Knuckles: Sandopolis Zone (Part 1) | 159 | Let's Play |
| 11. | Cybershell | Let's Play Sonic 3 & Knuckles: Mushroom Hill Zone (Part 2) | 158 | Let's Play |
| 12. | Cybershell | Let's Play Sonic 3 & Knuckles: Flying Battery Zone (Part 1) | 156 | Let's Play |
| 13. | Cybershell | Let's Play Sonic 3 & Knuckles: Death Egg Zone (Part 1) | 152 | Let's Play |
| 14. | Cybershell | Let's Play Sonic 3 & Knuckles: Sky Sanctuary Zone | 150 | Let's Play |
| 15. | Cybershell | Let's Play Sonic 3 & Knuckles: Sandopolis Zone (Part 2) | 142 | Let's Play |
| 16. | Cybershell | Let's Play Sonic 3 & Knuckles: Lava Reef Zone (Part 1) | 141 | Let's Play |
| 17. | Cybershell | Let's Play Sonic 3 & Knuckles: Death Egg Zone (Part 2) | 139 | Let's Play |
| 18. | KingSpartaX37 | Cloudsdale Sanctuary [MLP FIM x Sonic and Knuckles] | 108 | Let's Play |
| 19. | Kev Gaming XP | Let's Play Sonic & Knuckles Sega Genesis Finale Playthrough #3 | 107 | Let's Play |
| 20. | RetroGame.Stream | Sonic and Knuckles - Full Knuckles Playthrough | 98 | Let's Play |
| 21. | Cybershell | Let's Play Sonic 3 & Knuckles: Lava Reef Zone (Part 2) | 92 | Let's Play |
| 22. | Kev Gaming XP | Let's Play Sonic & Knuckles Sega Genesis Playthrough #2 | 87 | Let's Play |
| 23. | cobanermani456 | Sonic 3 and Knuckles - Playthrough Part 1 LIVESTREAM | 86 | Let's Play |
| 24. |  LETSPLAYmarkus | SONIC 3 & KNUCKLES A.I.R. # 12 🦔 Death Egg & The Doomsday Zone! | 76 | Let's Play |
| 25. | NintendoComplete | Sonic & Knuckles (Genesis) Playthrough | 72 | Let's Play |
| 26. | Jaypin88 | Sonic XG (Classic) ✪ Full Game (100%) Playthrough (1080p/60fps) | 62 | Let's Play |
| 27. | Kev Gaming XP | Let's Play Sonic and Knuckles Sega Genesis Playthrough #1 | 55 | Let's Play |
| 28. |  Green Hill Memories | [Let's Play #036] Sonic & Knuckles (Mega Drive - 1994) | 53 | Let's Play |
| 29. | LETSPLAYmarkus | SONIC 3 & KNUCKLES A.I.R. # 11 🦔 Hidden Palace & Sky Sanctuary Zone! | 52 | Let's Play |
| 30. | ZetaPlays | Let's Play Sonic and Knuckles 01 - Gotta Go Up (Also Fast) | 52 | Let's Play |
| 31. | HyperSonicX2 | Sonic 3 & Knuckles Playthrough 1 (Knuckles) | 50 | Let's Play |
| 32. | HellfireComms | Sonic Adventure DX playthrough [Knuckles] [Part 4] | 45 | Let's Play |
| 33. | SuperNardful | SuperNardful Plays Sonic & Knuckles (Full Game) | 41 | Let's Play |
| 34. | HellfireComms | Sonic Adventure DX playthrough [Knuckles] [Part 5] | 38 | Let's Play |
| 35. | Soulkrist | Mushroom Hill - Sonic & Knuckles [Knuckles Playthrough], Let's Play, Pt. 1 | 36 | Let's Play |
| 36. | Tomtil Lets plays | Sonic 3 AIR Let's Play Part 4 | 34 | Let's Play |
| 37. | Broken Mike | Sonic Mania "PLUS" | Sonic & Knuckles Let's Play Part 9 | Oil Ocean Zone | 31 | Let's Play |
| 38. | Retro Master | Sonic Mania - Super Peel-Out & Knuckles Playthrough | 25 | Let's Play |
| 39. | Soulkrist | Lava Reef - Sonic & Knuckles [Knuckles Playthrough], Let's Play, Pt. 4 | 24 | Let's Play |
| 40. | Tails' Channel | Matt and PKSparkxx (DatHottneSS) Play: Sonic 3 & Knuckles - Part 13 (FINALE) | 23 | Let's Play |
| 41. | SG Wolfie | Wolfie Plays Sonic & Knuckles: Newtronic Panic (Pre SAGE 2020) - Werewoof Reactions | 22 | Let's Play |
| 42. | ZetaPlays | Let's Play Sonic and Knuckles 02 - Gotta Walk Like An Egyptian (Also Disco Inferno) | 21 | Let's Play |
| 43. |  PlaysZeroX | O QUE VAI ACONTECER NA SÉRIE DO KNUCKLES?! FT. @SONIC_SPEED | LIVE DO PLAYSZEROX | 21 | Let's Play |
| 44. | HyperSonicX2 | Sonic 3 & Knuckles Playthrough 7 (Knuckles) | 20 | Let's Play |
| 45. | Therealm14 | Mushroom Hill Zone Act 1 Playthrough - By Therealm14 | 20 | Let's Play |
| 46. | Broken Mike | Sonic Mania "PLUS" | Sonic & Knuckles Let's Play Part 8 | Mirage Saloon Zone | 19 | Let's Play |
| 47. | HyperSonicX2 | Sonic 3 & Knuckles Playthrough 2 (Knuckles) | 19 | Let's Play |
| 48. | HyperSonicX2 | Sonic & Knuckles Playthrough 1 | 18 | Let's Play |
| 49. | bpblu | Sonic 3 & Knuckles Playthrough: Angel Island | 18 | Let's Play |
| 50. | ZetaPlays | Let's Play Sonic and Knuckles 03 - Gotta Shop Skymall (Also Ride The Rave Tubes) | 18 | Let's Play |
| 51. | ZetaPlays | Let's Play Sonic and Knuckles 04 - Gotta Hold My Breath In Space (Also Briefly Be Knuckles) | 17 | Let's Play |
| 52. |  Miggy | Sonic Advance 2 - Full Playthrough [Knuckles] | 17 | Let's Play |
| 53. | HyperSonicX2 | Sonic & Knuckles Playthrough 3 | 16 | Let's Play |
| 54. | Broken Mike | Sonic Mania "PLUS" | Sonic & Knuckles Let's Play Part 1 | Green Hill Zone | 16 | Let's Play |
| 55. | Broken Mike | Sonic Mania "PLUS" | Sonic & Knuckles Let's Play Part 12 | Titanic Monarch Zone (FINALE) | 16 | Let's Play |
| 56. | Tomtil Lets plays | Sonic 3 AIR Let's Play Part 6 | 16 | Let's Play |
| 57. | bpblu | Sonic 3 & Knuckles Playthrough: Final Boss & The Doomsday | 15 | Let's Play |
| 58. | Crow Continuum | Crow Plays Sonic & Knuckles (Genesis) | 15 | Let's Play |
| 59. | HyperSonicX2 | Sonic & Knuckles Playthrough 8 part 2 | 15 | Let's Play |
| 60. | Therealm14 | Flying Battery Zone Act 1 Playthrough- By Therealm14 | 15 | Let's Play |
| 61. | HyperSonicX2 | Sonic 3 & Knuckles Playthrough 16 (Knuckles) | 15 | Let's Play |
| 62. | Soulkrist | Flying Battery - Sonic & Knuckles [Knuckles Playthrough], Let's Play, Pt. 2 | 15 | Let's Play |
| 63. | Mike The Hedgehog | Sonic & Knuckles 1994 Sega Mega Drive Playthrough As Knuckles With Game Genie | 15 | Let's Play |
| 64. | GlobeTrottingGamers | Adam Plays: Sonic & Knuckles (Part 5) | 15 | Let's Play |
| 65. | Broken Mike | Sonic Mania "PLUS" | Sonic & Knuckles Let's Play Part 11 | Metallic Madness Zone | 14 | Let's Play |
| 66. | HyperSonicX2 | Sonic & Knuckles Playthrough 6 | 13 | Let's Play |
| 67. | Crow Continuum | Crow Plays Sonic & Knuckles with Sonic the Hedgehog 3 (Genesis) | 13 | Let's Play |
| 68. | Broken Mike | Sonic Mania "PLUS" | Sonic & Knuckles Let's Play Part 10 | Lava Reef Zone | 13 | Let's Play |
| 69. | GlobeTrottingGamers | Adam Plays: Sonic & Knuckles (Finale) | 13 | Let's Play |
| 70. | OGRagebreak Gaming | Recharge My Battery!🔋| Let's Play Sonic & Knuckles #02 (GEN) | 12 | Let's Play |
| 71. | HyperSonicX2 | Sonic & Knuckles Playthrough 5 | 12 | Let's Play |
| 72. | GameFace | Lets Play Sonic The Hedgehog 3 & Knuckles Gameplay Part 13 - Sonic & Knuckles: Final Boss Fight! | 12 | Let's Play |
| 73. | HyperSonicX2 | Sonic & Knuckles Playthrough 7 | 12 | Let's Play |
| 74. | Let's Play With Brigands | Let's Play Sonic 3 and Knuckles (Prequel Episode) | 12 | Let's Play |
| 75. | Soulkrist | Sandopolis - Sonic & Knuckles [Knuckles Playthrough], Let's Play, Pt. 3 | 12 | Let's Play |
| 76. | HyperSonicX2 | Sonic & Knuckles Playthrough 8 part 1 | 12 | Let's Play |
| 77. | DeliciousCinnamon | DC plays Sonic and Knuckles - Ep 1 | 11 | Let's Play |
| 78. | OGRagebreak Gaming | Sand Hell!😣| Let's Play Sonic & Knuckles #03 (GEN) | 11 | Let's Play |
| 79. | HyperSonicX2 | Sonic 3 & Knuckles Playthrough 4 (Knuckles) | 10 | Let's Play |
| 80. | Soulkrist | Hidden Palace/Sky Sanctuary - Sonic & Knuckles [Knuckles Playthrough], Let's Play, Pt. 5 | 10 | Let's Play |
| 81. | HyperSonicX2 | Sonic 3 & Knuckles Playthrough 6 (Knuckles) | 10 | Let's Play |
| 82. | GlobeTrottingGamers | Adam Plays: Sonic & Knuckles (Part 3) | 10 | Let's Play |
| 83. | Hotboy fresh / GPG Gaming | GPG let's play knuckles the enchilada / sonic & knuckles mushroom hill part 1 | 10 | Let's Play |
| 84. | CephasRed VS. | NOT WASTING ANY TIME | S3: Knuckles (Part 3) | 9 | Let's Play |
| 85. | Cyborcat | Let's Play Sonic & Knuckles (and chat) 3 | 9 | Let's Play |
| 86. | OGRagebreak Gaming | Eat The Mushroom!🍄| Let's Play Sonic & Knuckles #01 (GEN) | 9 | Let's Play |
| 87. | HyperSonicX2 | Sonic 3 & Knuckles Playthrough 13 (Knuckles) | 9 | Let's Play |
| 88. | HyperSonicX2 | Sonic & Knuckles Playthrough 2 part 1 | 9 | Let's Play |
| 89. | Sport Cards Brass Trains VideoGames | Sonic & Knuckles Sega Genesis PlayStation 2 Long Play Run | 9 | Let's Play |
| 90. | HyperSonicX2 | Sonic 3 & Knuckles Playthrough 3 (Knuckles) | 9 | Let's Play |
| 91. | Therealm14 | Flying Battery Zone Act 2 Playthrough by Therealm14 | 8 | Let's Play |
| 92. | RQ87 | Sonic & Knuckles playthrough (SEGA Saturn) | 8 | Let's Play |
| 93. | xCamarox | Sonic and Knuckles plays chess with Mordecai and Rigby | 8 | Let's Play |
| 94. | OGRagebreak Gaming | Super Mecha Revenge!😤| Let's Play Sonic & Knuckles #04 (GEN) [Finale!] | 8 | Let's Play |
| 95. | Cutman Plays! | Dj CUTMAN Remixing Sonic and Knuckles [Highlights] - Cutman Plays | 8 | Let's Play |
| 96. | WoolyMammoth27 | Sonic and Knuckles - Playthrough part 1 (No commentary) | 7 | Let's Play |
| 97. | ShadowMokujin | Sonic 3 and Knuckles Playthrough Death Egg Act 1&2 | 7 | Let's Play |
| 98. | Mike The Hedgehog | Sonic & Knuckles Sega Mega Drive Playthrough 1994 With Game Genie | 7 | Let's Play |
| 99. | HyperSonicX2 | Sonic 3 & Knuckles Playthrough 12 (Knuckles) | 7 | Let's Play |
| 100. | Therealm14 | Sky Sanctuary Zone Playthrough By Therealm14 | 7 | Let's Play |
