| 1. |  BlobVanDam | Sonic & Knuckles 3D - Mushroom Hill Zone | 6,787 | |
| 2. |  Freggie | The Sonic & Knuckles Show - & Knuckles | 2,958 | Show |
| 3. | Freggie | The Sonic & Knuckles Show - Child's Play | 2,867 | Show |
| 4. | outsidexbox | 6 Ridiculous Gimmicks Too Beautiful for This World | 2,790 | |
| 5. |  ALEC GO! #games | O SHIN SONIC TAPES ME INFECTOU, SOCORRO !!! 🧟 ROBLOX Sonic Morphs RP ( Alec GO! ) | 2,700 | |
| 6. |  TetraBitGaming | Sonic & Knuckles LOST BITS | Unused Content & Debug Features [TetraBitGaming] | 2,624 | |
| 7. |  Sonic David | Sonic and Knuckles Q&A #2 | 2,522 | |
| 8. | Freggie | Ask The Cast of The Sonic & Knuckles Show #1 | 2,296 | Show |
| 9. | Freggie | The Sonic & Knuckles Show - A Night to Remember | 2,101 | Show |
| 10. | Freggie | The Sonic & Knuckles Show - Monster Hunters | 2,072 | Show |
| 11. |  iTownGamePlay *Terror&Diversión* | SONIC AND KNUCKLES.EXE | 1,976 | |
| 12. | Freggie | The Sonic & Knuckles Show - A Meal For Two | 1,798 | Show |
| 13. | TASvidz | Sonic & Knuckles Speed Run (in 11 minutes, 57 seconds!) Knuckles any% | 1,791 | |
| 14. | Yo Mama | Yo Mama Jokes - YO MAMA SO FAT! Sonic & Knuckles | 1,273 | |
| 15. | Shadow | Sonic Encontra Ugandan Knuckles (Dublado em Português) | 1,227 | |
| 16. | AssopraFitas | A DOIDA FITA DE SONIC & KNUCKLES! feat. Videos de Clássicos | 1,161 | |
| 17. | RetroGame.Stream | Sonic & Knuckles - Sega Genesis - Full Sonic Playthrough No Commentary | 1,156 | Let's Play |
| 18. | DublandoCoisas | Knuckles No Filme Do Sonic | 1,125 | |
| 19. | Freggie | The Sonic & Knuckles Show - Zombie Apocalypse | 1,125 | Show |
| 20. | LankyBox World | CRAZIEST SONIC.EXE VIDEOS ON YOUTUBE! (SUNKY'S SCHOOLHOUSE, SONIC.EXE VS RAINBOW FRIENDS, & MORE!) | 1,120 | |
| 21. | Freggie | Shadow HATES Sonic?! - Ask Sonic & Friends (The Sonic & Knuckles Show Q&A) | 1,108 | Show |
| 22. | Pedro Araujo | SONIC & KNUCKLES Episode 5 Animation DOOMSDAY ZONE | 1,044 | |
| 23. | Jayp Dubla | O Show do Sonic & Knuckles: Caça aos monstros [DUBLADO PT-BR] | 1,034 | Show |
| 24. | Speedy Blue | KNUCKLES HATES PUDDINING! Sonic and Knuckles plays UNO | 974 | |
| 25. | Amy Rose Longplays | Sonic 3 & Knuckles (Genesis) - Longplay as Sonic & Tails | 950 | |
| 26. | DeoxysPrime | Flying Battery Zone Act 1 - Sonic Mania [OST] | 933 | |
| 27. | This Does Not Compute | Sega Ported Sonic 3 & Knuckles...to Windows? | 901 | |
| 28. |  NintenU | Sonic & Knuckles All Bosses | 895 | Guide |
| 29. |  김베포 | 🦠 모든 엔티티에 슬라임 코드를 집어넣은 결과 🦠 | 859 | |
| 30. | DavuuWart | Angel Island 2 (Sonic & Knuckles) #DavuuWart | 819 | |
| 31. | xMarcelo | SHADOW SONIC E KNUCKLES TRANSFORMÇÃO SECRETA ESCONDIDA COMO CONSEGUIR (Sonic Speed Simulator) | 805 | |
| 32. | Pai Troll | O JOGO MEME DO KNUCKLES! (KNUCKLES MANIA AND KNUCKLES) | 787 | |
| 33. | ElDescifrador27 | ¿EREN ES EL PADRE? | SNK 111-113 PREDICCIONES (TEORIA 104) | 757 | |
| 34. | Ph1LzA | Sonic & Knuckles :: Final Boss + The Doomsday ZONE + Credits :: 720p HD | 712 | |
| 35. | ProsafiaGaming | Sonic & Knuckles - All Bosses (No Damage) | 701 | |
| 36. | Captain Tate | Sonic And Knuckles Song #Shorts | 668 | |
| 37. | PressHeartToContinue | Top Ten Classic Game Songs!!! By The Way, Black Ops Is Out... | 665 | |
| 38. | DeoxysPrime | Doomsday Zone - Sonic & Knuckles [OST] | 618 | |
| 39. | Cybershell | Let's Play Sonic 3 & Knuckles: The Doomsday Zone | 581 | Let's Play |
| 40. | Chronicle2H | Sonic 3 and Knuckles Playthrough: Super Mecha Sonic (Knuckles) | 566 | Let's Play |
| 41. | World of Longplays | Mega Drive longplay - Sonic & Knuckles (part 1/2) | 550 | |
| 42. | longestsoloever | Sonic And Knuckles - Flying Battery Zone (ROCK GUITAR COVER) | 530 | |
| 43. | Sega Lord X | Sonic & Knuckles - Sega Genesis Review | 519 | |
| 44. | Sonic David | wæ (sonic and knuckles) | 517 | |
| 45. | Pedro Araujo | SONIC & KNUCKLES Episode 3 Animation | 513 | Show |
| 46. | Kane TV | SONIC & KNUCKLES 5 PARA NINTENDINHO | Sonic Fan Games #20 | 505 | |
| 47. | My Life in Gaming | Video Game Commercials of 1994 - Sonic & Knuckles, X-Men & More! / MY LIFE IN GAMING | 497 | |
| 48. | Slope's Game Room (Video Game Documentaries) | Sonic & Knuckles Secret Character - SGR (feat Death Mountaineers & Dreamcast Guy) | 450 | |
| 49. | setosorcerer | Sonic Craft 4 (Sonic & Knuckles) Part 1 w/ KKcomics and Gizzy Gazza! | 445 | |
| 50. |  Necros | Олдскульные посиделки. Sonic & Knuckles. Играем за супер Наклза ! | 444 | |
| 51. | UltimateDSfan | Insane Cartridge Tilting: Ep.4 - Sonic & Knuckles (Sega Genesis) | 439 | |
| 52. | Freggie | The Sonic & Knuckles Show - Eggman The Echidna | 416 | Show |
| 53. | Chary | SONIC vs KNUCKLES (Among Us) | 415 | |
| 54. | Freggie | BIG MUST BE STOPPED! - Ask Sonic & Friends (The Sonic & Knuckles Show Q&A) | 413 | Show |
| 55. | Flash Beats Manow | Rap do Knuckles (Sonic) - O Único Equidna | Flash Beats | 413 | |
| 56. |  LucasRPDJ | Sonic & Knuckles "Invincibility" theme Remix [Sprite Animated] | 404 | |
| 57. | ElDescifrador27 | LEVI VS EREN "ADIOS CAPITAN" | SNK 111 Y 112 PREDICCIONES | 402 | |
| 58. | Cryaotic | Livestream Tonight [11/29/14] | 399 | |
| 59. |  Luigikid Gaming | SONICANDKNUCKLES.EXE - YOU ARE A PIRATE! | 398 | |
| 60. | DeoxysPrime | Mushroom Hill Zone (Act 1) - Sonic & Knuckles [OST] | 391 | |
| 61. |  Kim Jenny 100 | Sonic VS Knuckles Prank Wars - Funny Couple Pranks - Sonic Spider-Man 2020 | 381 | |
| 62. | ParashockX | If Knuckles loses a ring, Knuckles becomes more modern | 375 | |
| 63. | León Picarón | EL TEAM SONIC EN LA PELICULA DE SONIC EN ESPAÑOL 2020 | TAILS Y KNUCKLES EN SONIC LA PELICULA LEON | 374 | |
| 64. |  Streview | סוניק 3 & נאקלס - ביקורת - Sonic 3 & Knuckles - Review - Hebrew | 373 | |
| 65. | RichaadEB | The Doomsday Zone - Sonic & Knuckles (Metal Cover by RichaadEB) | 371 | |
| 66. |  R3 Music Box | Flying Battery Zone/Sonic & Knuckles [Music Box] | 343 | |
| 67. | RichaadEB | Sonic 3 & Knuckles - Flying Battery Zone Act 1 [GUITAR COVER] | 342 | |
| 68. | DeoxysPrime | Flying Battery Zone (Act 1) - Sonic & Knuckles [OST] | 339 | |
| 69. | premydaremy | Sonic, Sonic, & Sonic Make A Sonic Tier List (Animatic) - Part 3 #sonic #sonicthehedgehog #soniccd | 328 | |
| 70. | Yuzoboy | Sonic & Knuckles - Flying Battery Zone Act 1(SNES remix) | 327 | |
| 71. |  caliburn | Knuckles Rates Persona 5 Girls | 320 | |
| 72. | premydaremy | Sonic, Sonic, & Sonic Make A Sonic Tier List (Animatic) - Part 2 #sonic #sonicthehedgehog #sonic2 | 320 | |
| 73. | Jayp Dubla | O Show do Sonic & Knuckles & Knuckles [DUBLADO PT-BR] | 319 | Show |
| 74. | Sergindsegasonic | Knuckles VS Mecha Sonic | Sonic & Knuckles (Historia de Knuckles) FINAL | 317 | |
| 75. |  Zyn | 【菜喳Sonic3】原來我們小時候玩這麼狂的遊戲XD 音速小子3和納克魯斯Sonic & Knuckles 3 Knuckles | 315 | |
| 76. | DeoxysPrime | Credits - Sonic & Knuckles [OST] | 313 | |
| 77. | Ben Briggs | Sonic & Knuckles - Flying Battery Zone Remix (Flight of the Battery) | 311 | |
| 78. | Ruki185 | Knuckles, Knuckles & Knuckles (Romhack) Showcase | 308 | |
| 79. | GaMetal | Sandopolis Zone (Sonic & Knuckles) - GaMetal Remix (2020 Revision) | 308 | |
| 80. | Магазин Денди | Картридж sonic & knuckles #retrogaming #денди #магазинденди #dendy #ретрогейминг #sega #сега | 307 | |
| 81. | DeoxysPrime | Sandopolis Zone (Act 1) - Sonic & Knuckles [OST] | 304 | |
| 82. | Core | A HISTÓRIA DE SONIC & KNUCKLES! | 303 | |
| 83. | Sergindsegasonic | La enchilada ataca de nuevo | Sonic & Knuckles (Historia de Knuckles) PARTE 1 | 301 | |
| 84. | ElDescifrador27 | EREN NUEVO REY! | SNK MANGA 110 MENTIRAS | ANALISIS COMPLETO:ESPAÑOL | 299 | |
| 85. |  جزيرة الأمل Hope Island | مغامرات القنفذ سونيك وصديقه ناكلز || Sonic and Knuckles ( Sega Genesis ) | 295 | |
| 86. | Aacro Xtensions | Knuckles' Theme (Sonic & Knuckles) - Sonic the Hedgehog 3 (& Knuckles) Music Extended | 293 | |
| 87. | Roger van der Weide | Sonic and Knuckles in 5 minutes | 292 | |
| 88. | MegaGWolf | SEGA SEGA SEGA | Sonic & Knuckles Corruption | 284 | |
| 89. | BRKsEDU | 2 Fitas AO MESMO TEMPO!? | Sonic & Knuckles e Suas Combinações! | 279 | |
| 90. | Speedy Blue | SONIC AND KNUCKLES GAY | 278 | |
| 91. |  OBI GAMER | SONIC & KNUCKLES GAME CARNIVAL NIGHT | 274 | |
| 92. | Razor & Zenon Sonic Videos | Sonic & Knuckles (Prototype 0606 - Jun 06, 1994, 10.02) - Walkthrough | 272 | Walkthrough |
| 93. | retrosutra | SONIC & KNUCKLES - VERSIONS Comparison ▶ EVOLUTION through its PORTS | 270 | |
| 94. | DeoxysPrime | Sky Sanctuary Zone - Sonic & Knuckles [OST] | 268 | |
| 95. |  davixd04 | ¡NO VALGO PARA NADA! - Mini Cómic - Por Sonic & Knuckles - "Fandub En Español Latino" | 267 | |
| 96. | TheLegendofRenegade | Sonic & Knuckles - Lava Reef Zone (Yoshi's Island Remix) | 267 | |
| 97. | DeoxysPrime | Sandopolis Zone (Act 2) - Sonic & Knuckles [OST] | 259 | |
| 98. | MugiMikey | Knuckles Needs Knuckles' Power - Movie Knuckles Vs. Game Knuckles Animated Parody Cartoon | 258 | Preview |
| 99. |  Roland Kenway | Knuckles rates Sonic Archie Girls #sonicthehedgehog #humor #memes #knuckles #waifu #shorts #chicas | 255 | |
| 100. | Cybershell | Let's Play Sonic 3 & Knuckles: Hidden Palace Zone | 248 | Let's Play |
