| 1. |  ELT Network | 831,489 | The Spider-Man 3 Remaster we NEED! | 5:12 |
| 2. | Reckless Comedy | 49,676 | Breaking up with Xbox for PS2 | PlayStation Girl | 6:15 |
| 3. | World of Electronics. AsH channel | 26,466 | Playstation 2 - Spider Man 3 | 8:39 |
| 4. | Addy Lovestar | 23,037 | Let's Play "Spider-Man 3" [PS3] - 6 - Bombs Away | 17:05 |
| 5. | TechUtopia | 14,150 | Pocophone F1 Spiderman 3 Wii game Dolphin test/Snapdragon 845 4X resolution | 7:08 |
| 6. | Evan Filarca | 11,167 | Radioactive Replay - Spider-Man 3 Part 4 - Rumble Down Under | 45:07 |
| 7. | COMICS PLUS! by Akasan | 9,242 | Tobey Maguire and Andrew Garfield have signed on for Spider-Man 3?! | 11:18 |
| 8. | Popcorned Planet | 7,287 | Tobey Maguire & Andrew Garfield for Spider-Man 3 !! Why's Grace Randolph Stealing This Exclusive?? | 9:59 |
| 9. | IGN | 5,856 | After Burner II PlayStation 2 Gameplay | 0:27 |
| 10. | ComicBookCast2 | 5,460 | Spider-Man 3 & MCU Delays, PlayStation 5 & Xbox, Movies on Demand & More l TCBC | 1:20:21 |
| 11. | Allie-RX | 5,353 | PS2 GAMES ON PS4 | Rant | 12:25 |
| 12. | KwingsLetsPlays | 4,434 | Spidey punch out #shorts Spider-Man | 0:33 |
| 13. | Natsya Gaming | 3,383 | New Suit Bio Electricity Texture - Spider-Man: 3 Wii [ Dolphin Emulator ] | 3:55 |
| 14. | Darth_Gamers | 2,241 | Spider-Man 3(PS2) - Let's Play Story - Part 10 | 18:24 |
| 15. | CraigS1996Entertainment | 2,057 | Spider Man 3: Playstation 2 Playthrough (Episode 12) | 23:50 |
| 16. | Gamer4Less | 1,933 | Hard to Find! Paid $99 Playstation 3 Spiderman 3 Collector's Edition Selling for $500 | 4:42 |
| 17. | Master Turkey | 1,845 | Spider-Man 3 - RPCS3 TEST (InGame) | 10:27 |
| 18. | Slyfincleton | 1,829 | Spider-Man 3 Playthrough (Part 3) | 3:18:13 |
| 19. | Fin Ravens | 1,826 | Spider-Man 3 Concession Ticket Variant on PlayStation 2 | 2:24 |
| 20. | NorthernFusionGames | 1,599 | Spider-Man 3 PlayStation 2 Walkthrough Part 11 Final Battle-Venom and Sandman | 22:04 |
| 21. | Boss Let's Play | 1,581 | Spider-Man Here To Save The World ! | 4:31:05 |
| 22. | LoneWolfXP 2 | 795 | I played Spider-Man 3 (PS3) in 2022! (First Playthrough) | 51:44 |
| 23. | DailyTested | 653 | OnePlus 7 Pro Spider-Man 3 Wii Android 10 Gameplay/Dolphin 5.0 MMJ gaming/Wii Emulatot test | 7:00 |
| 24. | Antonio Redgrave | 438 | The WORST Spider-Man Game!? | Road To Spider Man 2 | Spider-Man 3 Playthrough | 4:57:38 |
| 25. | Neon Cabaret | 337 | Spiderman 3.1 | Neon Cabaret | 8:09 |
| 26. | Cluckypower | 322 | Spider Man 3 The Game Full Playthrough Part 4 (Finale) | 1:17:00 |
| 27. | HowsItJoeIn | 314 | PCSX2 1.7.0 | Spider Man 3 HD 60FPS | PS2 Emulator Gameplay | 3:55 |
| 28. | Sc00pDaWh00p | 241 | Woah wait hey ahh crap - Let's Play - Spider Man 3 - Part 18 | 20:10 |
| 29. | THE DARK 007 | 239 | Spider-Man 3 Remastered - What are your thoughts on the game? | 8:06 |
| 30. | XI Dragoon | 215 | Spider-Man 3 Highlights | 17:10 |
| 31. | PlayStation World | 166 | Playstation 2 - Spider Man 3 | 10:01 |
| 32. | Cobra Jay | 143 | SpiderMan 3 MULTIVERSE Movie Not Happening Tom Holland Says... | 3:05 |
| 33. | Nate Masterson | 99 | Spider-Man 4 - Prototype - 4K - Wii - Dolphin - Core i7 2600 - GTX 970 | 15:52 |
| 34. | Tech2000 | 80 | PlayStation Store shutting down! | Hold onto PS3, PSP, and PS Vita games, HERES WHY! | 5:50 |
| 35. | Builder Mario - Nintendo Gameplays | 75 | Ethan Plays SpiderMan 3 GameBoy Advance Part 1 | 8:13 |
| 36. | Jay Fridge | 53 | Insomniac Games is RESILIENT… | 8:12 |
| 37. | BIDUZ | 50 | Spiderman 3 | HAMMANI QUTQARAMIZ#1 | Uzbekcha LETSPLAY | 15:28 |
| 38. | Punkinnonstop | 50 | Spiderman 3 PS2 | Episode 1 | Big Flings | PunkinRePlays | 5:50 |
| 39. | JET10 Gaming | 38 | Sony PlayStation 2's Spider-Man 3 Intro | 1:01 |
| 40. | RAH KLASSIC | 33 | Playa Peter Parker & Maccin Miles!! 1st Spiderman 3 Playthrough! PS5 | 32:18 |
| 41. | Valtvalko | 31 | It's My Birth Day (4 gameplays) (march 10 2021) | 1:48:32 |
| 42. | tvsonicgaming | 27 | PlayStation News, Spider-Man 3 No Way Home, Pokémon Cards | The Travis and Damian Podcast Episode 62 | 1:34:00 |
| 43. | Last Pc Gamer | 25 | SHE TRYING TO SMASH, Y'ALL!!! Lets Play: Spider-Man 3 | HD Gameplay | | 23:21 |
| 44. | Arkknight | 16 | Spider-Man 3........ Help ME!!!!!!! | 3:43:27 |
| 45. | Алекс Крюгер | 12 | Spider Man 3 I'm Going To Die #Shorts #SpiderMan #Game #QTE #Fail #Gameplay #Marvel #SP3 #Die #Help | 0:10 |
| 46. | Supermodel Gaming | 10 | A Cry For Help - Dewolfe 1 [Spider-Man 3] | 3:12 |
| 47. | Action Talk | 5 | Scott plays Spider-man 3/11/19 | 59:19 |
| 48. | Lymezy | 4 | CARNAGE? IS THIS A Spider-Man 3 EASTER EGG?! | Yuri Finale | 16:05 |
