| 1. |  Fimlar | 2,929,449 | Záznam z LiveStreamu 19:05.2016 Isaac 2 | 1:15:03 |
| 2. | DustElite | 1,016,245 | The Binding of Isaac - Eternal Edition (#4) | 33:55 |
| 3. | MenT | 94,348 | [Indie hry]The binding of isaac | 16:18 |
| 4. | Krteto | 42,197 | Náhodné video - TBoI - WoTL - Ajzikerino | 1:09:14 |
| 5. | SmusaGames | 27,044 | Co mi zbylo z The Binding of Isaac ktery jsem nenahraval O_o | 2:21 |
| 6. | Pufeek | 14,523 | (Wallaby Lukasino) - The Binding of Isaac: Wrath of the Lamb - 1.část | 56:17 |
| 7. | StaySteak | 13,780 | [LP] The Binding of Isaac - SADBOY 2015 (CZ) | 16:20 |
| 8. | Nakashi | 9,467 | BROTATO - Skvělá Bramboří Roguelike hra - Nakashi | 44:46 |
| 9. | Hrej.cz | 8,318 | 24 hodinový stream s Hrej.cz (2/3) | 7:46:10 |
| 10. | GMSVidea | 6,076 | [Indie Speciál 12.12] - The Binding of Isaac: Wrath of the Lamb - [GMSVidea][CZ] | 30:13 |
| 11. | FlyGun+ | 5,794 | The Binding of Isaac - FlyGunCZ part 11 | 1:10:17 |
| 12. | INDIAN - Czech TV Gaming Show | 5,079 | Wrii brečí při hraní The Binding of Isaac - 🔴 Liveplay | 1:44:56 |
| 13. | CzechCloud Gaming | 3,079 | Bethany - The Binding of Isaac | 7.4.2024 | 1:16:48 |
| 14. | WheeGameplays | 2,854 | [CZ] Let's Play: Binding of Isaac #4 | 19:22 |
| 15. | Za-play.cz | 2,824 | Nakashi - Záznam streamu - The binding of Isaac, Minecraft, Agar.io, Dobyvatel [CZ] | 2:45:39 |
| 16. | Mikin | 2,203 | [Mikin][Stream] Back to the basement --- The Binding of Isaac | 6:31:17 |
| 17. | Maaya | 2,160 | The Binding of Isaac - time lapse painting | 3:42 |
| 18. | Isaac Better | 868 | I don't like Eve at all - Binding of Isaac: Run 61 | 29:33 |
| 19. | DRAK | 793 | [LP] Dracek.cz - LS : The Binding of Isaac + Monaco "cz" - [HD] | 3:49:00 |
| 20. | Mlemi | 520 | Isaac vs CZ/SK Streameři 🤩 | The Binding of Streamers | 17:38 |
| 21. | Pařanský ráj | 315 | The Binding of Isaac | Český gameplay indie rogue-like pecky | CZ Gameplay 1080p | 2:09:43 |
| 22. | Dykol | 176 | Hra Binding of Isaac mě potrollila! | 0:25 |
| 23. | TeamGamesOver | 165 | TeamGamesOver - Undertale a The Binding of Isaac ! (Webcamera) | 2:50:45 |
| 24. | Johnden | 140 | Charged | TBoI: Repentance Daily Run [February 10, 2023] | 0:00 |
| 25. | Jax49Gameplay | 129 | cannot translate but it might have been something about my own projectile | 0:16 |
| 26. | B0wser998 | 126 | The Binding of Isaac (WOTL) | #4 | 0:00 |
| 27. | Alfapiomega | 117 | Let's Hang Out With Isaac - part 2 "Random Stuff" | 58:28 |
| 28. | KeenGamer - More Than Just a Game Site | 115 | Princess. Loot. Pixel. Again - Let's play | 11:50 |
| 29. | Kosťa & Silvie | 112 | Kvalitní video o h*vně ... doslova | The Binding of Isaac | | 7:53 |
| 30. | Kubasak | 55 | The Binding Of Isaac: Wrath Of The Lamb | Isaac mi vůbec nejde!!! | 17:45 |
| 31. | SlyCyanide | 41 | The Binding Of Isaac Four Souls Requiem The Full Collection Box UNBOXING | 34:43 |
| 32. | Spejs | 39 | 🔴 19.12.2024 🔴 CS2 s Jezevcem a Bratránkem The Binding of Isaac | 0:00 |
| 33. | EXONERV | 28 | Одиннадцатый Стрим (Isaac + Project Zomboid) | 3:55:24 |
| 34. | akmaVODs | 20 | Epic Lost run against The Mother!!1! | 1:05:23 |
| 35. | Nethrix | 12 | The Binding of Isaac: Most clutch and intense Mother Fight EVER!! | 4:43 |
| 36. | Lukýsek | 8 | Binding of Isaac 2023 05 27 19 36 29 | 4:24 |
| 37. | Sfroto | 0 | The binding of isaac repentanc normal stream | 0:00 |
