| 2025-07-18 |  Rab(BIT)ie | 23 | from the basement to the mountains - Binding of Isaac/Peak | 0:00 |
| 2025-05-28 | BeeVeelutions Twitch Archive | 281 | NOW THATS A LOT OF TRINKETS | #beeveelutions on #Twitch #bindingofisaac #twitchclip #fyp | 0:00 |
| 2025-04-21 | Mewkel_ | 119,000 | KÆFT HAN ER TYK! (Binding of Isaac) - Mewkel [Re-Upload] | 0:00 |
| 2024-11-22 | jam | 935 | ISAAC ONLINE RAAAAAH | 0:00 |
| 2023-07-31 | FreakyFreddysCaveOfWonder | 891 | I.Rule (Part 1) | 1:48:31 |
| 2023-07-19 | MythyMoo | 628,000 | I played 7 of the WORST Rogue-Like games so you don't have to | 28:25 |
| 2023-05-26 | RasMovies | 535 | (DANSK) The Binding of Isaac Clarke - Dead Space Remake | 1:45:48 |
| 2023-02-06 | SolVezon | 92 | Reto si muero se acaba el video 6# | TBOI Repentance | maldita maquina de donaciones | 11:16 |
| 2023-02-01 | void crusader | 3,480 | MOBS, INC ★ by OVERBOY ツ first video with new mic | 5:59 |
| 2022-04-26 | Lucas | 19 | Outplayed with Zanatron | The binding of Isaac | 0:12 |
| 2022-03-06 | Why Always | 2,260 | the binding of isaac chemical peel in real life | 0:44 |
| 2021-09-02 | Molle | 8,050 | VI SKAL SLÅ MOR IHJEL! | Binding Of Isaac #2 | 2:18:38 |
| 2021-07-11 | BP_DM - VODs | 15 | BP_DM | The Binding of Isaac + Amnesia: Rebirth | Full Stream | 4:01:30 |
| 2021-03-23 | Svinet | 323 | The Binding of Isaac (Full playthrough) | 43:55 |
| 2020-12-29 | ThatInsaneDane | 11,400 | Dane Plays: The Binding of Isaac - Random run [P2] [Dec. 29] | 43:02 |
| 2016-01-29 | Kimo | 441 | How To Never Lose In The Binding Of Isaac | 2:07 |
| 2015-08-20 | KlausGaming | 2,000 | Fingered Gameplay - New Game by Edmund McMillen - Fingered Gameplay PC - Let's Play Fingered | 9:55 |
| 2014-11-03 | Madi Renai | 557 | [Let's Play] Isaac: Communiy Remix - #16 Cheats | 40:15 |
| 2014-10-06 | Lasse Vestergaard | 182,000 | Liv & Død - Binding of Isaac (Isaac udfordring!) | 35:45 |
| 2014-05-19 | Linnet's Gameplay & Reviews | 422 | Crafting Isaac tier 2 badge Maggy | 0:21 |
| 2014-03-10 | Gibocraft | 21,100 | Ben - The Binding Of Isaac - MONEY = POWER! #6 | 28:37 |
| 2013-08-02 | BB Steam Review | 18,400 | Binding Of Isaac Wrath Of The Lamb Ep 1 | 36:50 |
| 2013-05-30 | Auriga | 163 | The Binding of Isaac - Episode 6 " The Journey to The Land Of Uterus " | 46:49 |
| 2012-11-23 | Hasax | 5,760 | EgoGamers - Binding of Isaac | 29:39 |
