| 1. |  MrAntouon | ΑΤΟΝΗ ΤΙ ΠΑΙΖΕΙΣ ΡΕ!??! | 123,564 | |
| 2. | Zok | Happy 32 Breathday Stream (#1 - Issac, MSGV) | 15,273 | |
| 3. | Zok | Binding of Isaac x18 (The Polaroid) | 12,548 | |
| 4. | Zok | Binding of Isaac x17 (Holier Than Thou) | 12,420 | |
| 5. | Zok | Zok Streams: Τα 30στα γενέθλια του.(Μέρος 2) | 10,004 | |
| 6. | Zok | Binding of Isaac x16 (Blue Baby) | 5,682 | |
| 7. | The Kouzins | ΟΙΚΟΓΕΝΕΙΑΚΗ ΥΠΟΘΕΣΗ ! | The Binding of Isaac | 2,440 | |
| 8. | pontikakiGR | The Binding of Isaac - Μητέρα, μανούλα, μαμά (Gameplay) | 1,489 | |
| 9. | The Kouzins | ΕΝΑ Binding Of Isaac με όπλα??? | 1,434 | |
| 10. | GameWorld.gr | Παίζουμε The Binding Of Isaac - Part 1 | 1,275 | |
| 11. | The Kouzins | Ας Παίξουμε Binding of Isaac Live 27/10/14 | 1,182 | |
| 12. | pontikakiGR | Bindind of Isaac: Wrath of the Lamb ~ In Depth Guide 4 Dummies [Με τη Μελ] | 1,065 | |
| 13. | GameWorld.gr | Παίζουμε The Binding Of Isaac - Part 2 | 701 | |
| 14. | GameWorld.gr | The Binding of Isaac #3: Wrath of the lamb DLC | 600 | |
| 15. | DRAGOMAN | 24/1/16 THE BINDING OF ISAAC 4SOMMMM TROLL LIVESTREAM HIGHLIGHT | 450 | |
| 16. | TIMIOI ASSASSINOI (T.A) | ΑΝΑΚΟΙΝΩΣΗ!!! (Binding of Isaac Mega Satan boss fight) | 244 | |
| 17. | BioroboticGaming | Binding Of Isaac Massacre: How to kill the BEAST | 168 | |
| 18. | BioroboticGaming | ALL Lilith's Achievements-Unlocks in LESS Than a Minute #bindingofisaac #shorts | 159 | |
| 19. | Nicola Void | Nicola plays : The Binding of Isaac AB+ Ep.0 [ Failed Pilot / Τέσσερις Καβαλάρηδες της Αποκάλυψης ] | 156 | |
| 20. | Bestof Tsounami | The Binding of Isaac You will never defeat me (και μπορει) | 102 | |
| 21. | Bestof Tsounami | The Binding of Isaac Episode 2 λιγο πριν την μαμα | 99 | Show |
| 22. | Bestof Tsounami | The Binding of Isaac ατυχια | 83 | |
| 23. | Bestof Tsounami | Binding of Isaac First Time mom | 69 | |
| 24. | Velia | The Binding of Isaac: Four Souls Requiem Ultimate Collector's Box KS Edition Part 1 (VOD) | 51 | |
| 25. | Velia | The Binding of Isaac: Four Souls Requiem Ultimate Collector's Box KS Edition Part 2 (VOD) | 50 | |
| 26. | BioroboticGaming | Isaac and Cain melting BEAST | 40 | |
| 27. | InsaneM | InsaneM The Binding of Isaac | 33 | |
| 28. | PixelFansGR | Dat mom...-Binding of Isaac #1 | 31 | |
| 29. | Velia | The Binding of Isaac: Four Souls Requiem Ultimate Collector's Box KS Edition Part 3 (VOD) | 30 | |
| 30. | Kyatto-san | O Kyatto παίζει The Binding of Isaac | 28 | |
| 31. | Babaja | The Binding of Isaac Ειναι για το POYTSO! και κατι σαν update | 26 | Vlog |
| 32. | InsaneM | The Binding of Isaac - Tainted Eve vs. Greedier (EPIC FAIL) | 26 | |
| 33. | InsaneM | InsaneM The Binding of Isaac | 25 | |
| 34. | Evans X Games | The Binding Of Isaac_Η Σχιζοφρένης Μητερα (Road To 400 Subscribers) | 25 | |
| 35. | Dizas YGC | Ζωντανή ροή Dizas YGC | 24 | |
| 36. | InsaneM | The Binding of Isaac - Tainted Lilith vs. Mega Satan | 16 | |
| 37. | InsaneM | The Binding of Isaac - Bethany vs. Beast & Isaac vs. Greedier | 15 | |
| 38. | InsaneM | The Binding of Isaac - Lilith & Bethany vs. Hush (and a bunch of victory laps) | 15 | |
| 39. | InsaneM | The Binding of Isaac - Killing the beast with tainted Sampson??? | 13 | |
| 40. | InsaneM | InsaneM The Binding of Isaac | 10 | |
| 41. | BioroboticGaming | The Binding Of Isaac unlimited hearts | 9 | |
| 42. | InsaneM | The Binding of Isaac - Killing Greed with '???' and Magdalene | 9 | |
| 43. | Dizas YGC | Ζωντανή ροή Dizas YGC | 9 | |
| 44. | InsaneM | The Binding of Isaac - POOP! (Tainted '???' vs. Greedier) | 9 | |
| 45. | petsasjim1 | THE BINDING OF ISAAC TRIBUTE GAME VOXATRON Fantasy Virtual Console Lexaloffle Games wwwlexalofflecom | 9 | |
| 46. | InsaneM | The Binding of Isaac - Bethany vs. Mother | 8 | |
| 47. | InsaneM | The Binding of Isaac - tainted Apollyon Victory Lap! | 7 | |
| 48. | InsaneM | Some Overwatch | 7 | |
| 49. | InsaneM | The Binding of Isaac - tainted Lost vs. Greedier. Lost! | 6 | |
| 50. | InsaneM | The Binding of Isaac - Tainted Eve finally killing Greedier | 6 | |
| 51. | InsaneM | The Binding of Isaac - rush for Hush | 6 | |
| 52. | InsaneM | The Binding of Isaac - another rush for Hush | 5 | |
| 53. | InsaneM | The Binding of Isaac - Unlocking tainted Keeper & killing Greedier | 5 | |
| 54. | Lobster Official | The Binding Of Isaac Afterbith + Pokey Mans I Was In Love With an Eye | 5 | |
| 55. | InsaneM | The Binding of Isaac - another another rush for Hush | 4 | |
| 56. | InsaneM | The Binding of Isaac - trying out the Keeper | 3 | |
| 57. | InsaneM | The Binding of Isaac - Isaac hunting the Beast in Hard Mode | 3 | |
| 58. | InsaneM | The Binding of Isaac - Boss Rush | 2 | |
| 59. | DeathshadeGR | [GR] DV Roguelikes ! Παίζουμε γνωστά και άγνωστα Roguelikes ! | Binding of Isaac PC Co - Op #1 ! | 0 | |
