| 1. |  WWEdeadman | 997 | Tainted Isaac to the Chest - The Binding of Isaac: Repentance #79 | 58:57 |
| 2. | Himsl Games | 205 | Retarded Manchild defends the Emoji Moji! | 18:28 |
| 3. | Tom Henks | 67 | Tom Plays Afterbirth - Ep. 3 [Speed] | 27:52 |
| 4. | orizuru | 55 | The Binding of Isaac - Afterbirth+ - The Forgotten vs Blue Baby | 1:07:45 |
| 5. | HofiLP | 49 | Das Knive muss ordentlich zustechen! - The Binding of Isaac: Repentance (HofiLP am 06.12.2023) | 1:58:13 |
| 6. | PKWeegee1337 | 39 | Paper Mario: TTYD - Episode 61 - Cogs of Darkness | 13:55 |
| 7. | ErkandorLP | 29 | Ein lustiger, kleiner Isaac-Run | 1:27:04 |
| 8. | Muffet | 21 | Test isaac runs | 58:08 |
| 9. | Bindey | 13 | Rocket In A Jar Explained - The Binding Of Isaac: Repentance | 3:37 |
| 10. | berkus | 10 | Wie lange schaffen wir es mit schlechten Items? | Binding of Isaac: Repentance | 0:00 |
| 11. | Biggy&Stepsi | 8 | The Binding of Isaac 💀 Wir machen ein paar Runs 🔴 Live | 1:21:51 |
| 12. | Mr.Thomsn | 8 | VICTORY LAP MODE | The Binding of Isaac Afterbirth+ | 20:22 |
| 13. | Estrana | 7 | Pillenhafte Beauty Fly | Isaac Afterbirth | Folge 5 | 53:03 |
| 14. | geistreiches | 7 | #SPIDERCAM ... The Binding of Isaac [ENG] - STREAM #8 | 1:13:27 |
| 15. | GaryTheGerman-rid | 7 | UnderMine | Das neue Isaac? | Part 1 [German/angezockt] | 43:13 |
| 16. | Zelpnir | 6 | Mein Lieblingsgame - The Binding of Isaac: Rebirth - INDIE FEEDBACK #001 | 3:55 |
| 17. | WWEdeadman VOD Channel | 4 | The Binding of Isaac Repentance - Stream VOD #4 | 1:59:25 |
| 18. | HolyFistHD Archiv | 4 | The Binding of Isaac - Afterbirth+ (Switch) #04 - 2017 | 1:03:23 |
| 19. | DomsUncutChannel | 4 | (Ger) The Binding of Isaac Afterbirth 4 (PS4 Gameplay) | 40:24 |
| 20. | MikaMewMew🩷 | 3 | The Hard Carry of Isaac | 24:41 |
| 21. | SafeWillow | 3 | The Binding of Isaac Afterbirth + | #3 Glück mit Cain/Blue Baby | 1:05:56 |
| 22. | Videograb | 3 | Harry Potter Fail, The Binding of Isaac: Afterbirth #017, Portal 2 #001 [PC] [FullHD] | 3:19:58 |
| 23. | TouchGameplay | 3 | The Binding of Isaac Rebirth (by Nicalis, Inc.) - iOS - HD LiveStream | 1:47:46 |
| 24. | Luigikid Gaming | 3 | SATELITE RUSH - SCI-FI THE BINDING OF ISAAC [KICKSTARTER DEMO] | 10:14 |
| 25. | Wyzau | 2 | Robot Legions Reborn Gameplay #1 | 42:46 |
| 26. | AaronTheBlackDragon | 2 | 'RS' Boss Rush Apocalypse -Go for the Head- | 7:38 |
| 27. | Alextv98 | 1 | Do it! - Friendgesteuert | mit Rappi und The Binding of Isaac: Afterbirth + | #2 | 1:16:30 |
| 28. | Christensen | 1 | Switch vs. Steam Deck! #nintendo #switch #steamdeck #console #controller #stickdrift #zocken | 0:28 |
| 29. | headfullASMR | 1 | ASMR The Binding of Isaac Rebirth GERMAN | 16:50 |
| 30. | Alex 灰色 | 1 | ADVENTSKALENJDER TÜRCHEN 14 The Binding of Isaac Rebirth | 46:26 |
| 31. | Newsroom Fab | 1 | Infos (The Binding Off Isaac News) | 8:27 |
| 32. | Panteqz Plays | 1 | THE BINDING OF ISAAC REBIRTH ✘ ANGEZOCKT #11 | Panteqz | 8:59 |
| 33. | ThreeTwoPlay | 1 | Special - The Binding of Isaac: Repentance #001 | 2:36:28 |
| 34. | LordDova | 1 | 1) Heul dich durch, Isaac | 11:05 |
| 35. | KaiZar | 1 | BROKEN MODEM ist OP! | 18:40 |
| 36. | Zeaod | 1 | The Binding of Isaac Livestream with the Boyz #1 | 2:48:09 |
| 37. | Weird Eurasian Boy | 1 | Live Commentary 6 [The Binding of Isaac: Rebirth gameplay] | 24:54 |
| 38. | Abseudus | 1 | Let's Stream Binding of Isaac + Diskussionsrunde | 1:59:25 |
| 39. | Tentacle Gaming | 1 | The Binding of Isaac: Rebirth | Angezockt [Deutsch/PS4] | 27:01 |
| 40. | BLOGDOT.TV | 1 | The Binding of Isaac Rebirth Gameplay Video | 5:08 |
| 41. | RKR | 1 | Let's Stream Super Mario Maker 2 (21.4.2024) + The Binding of Isaac Repentance | 3:27:36 |
