| 1. |  TearofGrace | The Binding of Isaac REBIRTH: SOY MILK + QUAD SHOT + SCYTHES + CHOCOLATE MILK | 3,284,244 | |
| 2. | TearofGrace | The Binding of Isaac AFTERBIRTH: PENNY TEARS + MONSTRO'S LUNG + POLYPHEMUS | 2,720,055 | |
| 3. | TearofGrace | The Binding of Isaac AFTERBIRTH: BRIMSTONE + EPIC FETUS + BUTT BOMBS | 2,395,581 | |
| 4. | TearofGrace | The Binding of Isaac AFTERBIRTH: LILITH + BFF + MAGIC MUSHROOM | 2,249,692 | |
| 5. | TearofGrace | The Binding of Isaac AFTERBIRTH: BRIMSTONE + MONSTRO'S LUNG + MOM'S KNIFE + BOUNCING TEARS | 2,020,078 | |
| 6. | TearofGrace | The Binding of Isaac REBIRTH: IPECAC + QUAD SHOT + LOKI'S HORNS + ORBITING TEARS | 2,015,640 | |
| 7. | TearofGrace | The Binding of Isaac AFTERBIRTH: HUSH VS TECH X + SPOON BENDER | 1,933,502 | |
| 8. | TearofGrace | The Binding of Isaac REBIRTH: BRIMSTONE + LUDOVICO + SPOON BENDER | 1,896,882 | |
| 9. | TearofGrace | The Binding of Isaac AFTERBIRTH: DR FETUS + TECH X + TECH 2 + BOUNCING TEARS | 1,892,407 | |
| 10. | TearofGrace | JACOB'S LADDER + SOY MILK + 16 SHOT + SPLASH DAMAGE | The Binding of Isaac: AFTERBIRTH PLUS Gameplay | 1,888,794 | |
| 11. | TearofGrace | BEST BRIMSTONE BUILD EVER (Hydrophobicity Mod) | AFTERBIRTH PLUS Gameplay | 1,852,269 | |
| 12. | TearofGrace | The Binding of Isaac REBIRTH: BLUE BABY VS. MEGA SATAN | 1,832,635 | |
| 13. | TearofGrace | The Binding of Isaac REBIRTH: TRIPLE SHOT + SPLIT SHOT + GIANT TEARS | 1,830,040 | |
| 14. | TearofGrace | The Binding of Isaac REBIRTH: POLYPHEMUS + PROPTOSIS + BABYLON | 1,725,623 | |
| 15. | TearofGrace | TETRACHROMACY, MOST BEAUTIFUL & BROKEN MOD EVER | AFTERBIRTH PLUS Gameplay | 1,671,628 | |
| 16. | TearofGrace | The Binding of Isaac AFTERBIRTH: ULTRA GREED GOES BROKE | 1,644,876 | |
| 17. | TearofGrace | The Binding of Isaac REBIRTH: MONSTRO'S LUNG + CHOCOLATE MILK + SCYTHES | 1,627,365 | |
| 18. | TearofGrace | The Binding of Isaac REBIRTH: IPECAC + TRIPLE SHOT + FIRE MIND = NAPALM | 1,622,308 | |
| 19. | TearofGrace | The Binding of Isaac REBIRTH: BRIMSTONE + MOM'S KNIFE + MOM'S EYE | 1,616,819 | |
| 20. | TearofGrace | DR. FETUS + CHOCOLATE SOY MILK + TECH X + SPLASH DAMAGE | The Binding of Isaac: Afterbirth Gameplay | 1,608,956 | |
| 21. | TearofGrace | THE MASKED MAN (Oculus Rift + Lodestone) | The Binding of Isaac: ANTIBIRTH Gameplay | 1,604,099 | |
| 22. | TearofGrace | The Binding of Isaac REBIRTH: ISAAC ROLLS OVER ??? | 1,601,781 | |
| 23. | TearofGrace | The Binding of Isaac REBIRTH: BRIMSTONE + TRIPLE SHOT + BABYLON | 1,589,488 | |
| 24. | TearofGrace | The Binding of Isaac AFTERBIRTH: IPECAC + CHOCOLATE MILK + DOUBLE TRIPLE SHOT | 1,557,846 | |
| 25. | TearofGrace | THE VOID + DELIRIUM'S ENDING | The Binding of Isaac: AFTERBIRTH+ Gameplay | 1,502,756 | |
| 26. | TearofGrace | CONTROLLED TRIPLE BRIMSTONE VS THE WITNESS | The Binding of Isaac: ANTIBIRTH Gameplay | 1,485,895 | |
| 27. | TearofGrace | BOUNCE (Soy Milk + Double Triple Rubber Scythes) | The Binding of Isaac: Afterbirth Gameplay | 1,426,214 | |
| 28. | TearofGrace | The Binding of Isaac AFTERBIRTH: IPECAC + SOY MILK + GUPPY (MissingNo Insanity) | 1,364,889 | |
| 29. | TearofGrace | SOY MILK + HAEMOLACRIA BRIMSTONE BREAK | AFTERBIRTH PLUS Gameplay | 1,326,043 | |
| 30. | TearofGrace | NEW FLOOR, ENEMIES, EVERYTHING (DIRTY MIND/Poo Army) | The Binding of Isaac: ANTIBIRTH Gameplay | 1,319,744 | |
| 31. | TearofGrace | The Binding of Isaac AFTERBIRTH: THE LOST VS ULTRA GREED | 1,311,890 | |
| 32. | TearofGrace | The Binding of Isaac REBIRTH: POLYPHEMUS + SCYTHES + IPECAC | 1,278,486 | |
| 33. | TearofGrace | The Binding of Isaac AFTERBIRTH: THE KEEPER TECHNICALLY GETS GREEDY | 1,272,473 | |
| 34. | TearofGrace | The Binding of Isaac REBIRTH: DR FETUS + PYROMANIAC + MR MEGA | 1,266,538 | |
| 35. | TearofGrace | KAMIKAZILLER (DR MONSTRO'S SCATTER BOMBS + PYROMANIAC) | The Binding of Isaac: Afterbirth Gameplay | 1,260,614 | |
| 36. | TearofGrace | The Binding of Isaac AFTERBIRTH: TECH X + EPIC FETUS + MONSTRO'S LUNG | 1,252,253 | |
| 37. | TearofGrace | The Binding of Isaac AFTERBIRTH: DR FETUS + MONSTRO'S LUNG + SPLIT SHOT | 1,249,126 | |
| 38. | TearofGrace | 20 20/20s (Max Transformation Mod) | AFTERBIRTH PLUS Gameplay | 1,243,254 | |
| 39. | TearofGrace | MOST BROKEN BUILD EVER | AFTERBIRTH PLUS Gameplay | 1,235,373 | |
| 40. | TearofGrace | THE MOST AMAZING SYNERGIES WITH ONE MOD (Model Rocket Mod) | AFTERBIRTH PLUS Gameplay | 1,224,901 | |
| 41. | TearofGrace | The Binding of Isaac REBIRTH: MONSTRO'S LUNG + CHOCOLATE MILK + CRICKET'S HEAD | 1,221,499 | |
| 42. | TearofGrace | The Binding of Isaac REBIRTH: CAIN BECOMES THE REAPER | 1,208,530 | |
| 43. | TearofGrace | The Binding of Isaac: AFTERBIRTH-GOD MODE | THE MASKED VS THE SOULLESS | 1,207,737 | |
| 44. | TearofGrace | The Binding of Isaac REBIRTH: IPECAC + PYROMANIAC + MONSTRO'S LUNG + ORBITING TEARS | 1,204,244 | |
| 45. | TearofGrace | The Binding of Isaac AFTERBIRTH: TECH X + MONSTRO'S LUNG + CTHULHU + BUMBO | 1,193,798 | |
| 46. | TearofGrace | JACOB'S LADDER + DOUBLE SPLIT SHOT + SINUS INFECTION | The Binding of Isaac: AFTERBIRTH+ Gameplay | 1,187,015 | |
| 47. | TearofGrace | The Binding of Isaac REBIRTH: MOM'S KNIFE + QUADSHOT | 1,179,948 | |
| 48. | TearofGrace | THE FORGOTTEN FUN (Mom's Knife + Loki's Horn & more...) | TBOI Afterbirth Plus | 1,147,128 | |
| 49. | TearofGrace | The Binding of Isaac REBIRTH: BRIMSTONE + SPOON BENDER + ANTI GRAVITY | 1,138,760 | |
| 50. | TearofGrace | HOMING BOUNCING BROKEN BRIMSTONE BUILD (Light Shot Mod) | AFTERBIRTH PLUS Gameplay | 1,130,911 | |
| 51. | TearofGrace | DELIRIOUS WITNESS VS CHILD ARSONIST | The Binding of Isaac ANTIBIRTH Gameplay | 1,129,296 | |
| 52. | TearofGrace | The Binding of Isaac REBIRTH: THE MISSINGNO OP COMBO | 1,121,198 | |
| 53. | TearofGrace | The Binding of Isaac REBIRTH: LUDOVICO + QUADSHOT + LAZER TEARS | 1,116,004 | |
| 54. | TearofGrace | The Binding of Isaac REBIRTH: SAMSON & THE LAMB | 1,115,469 | |
| 55. | TearofGrace | The Binding of Isaac REBIRTH: SCYTHES + CRICKET'S BODY + PROPTOSIS | 1,115,367 | |
| 56. | TearofGrace | The Binding of Isaac REBIRTH: THE LOST + MOM'S KNIFE + ORBITING TEARS | 1,111,565 | |
| 57. | TearofGrace | SAMAEL MOD (Tractor Beam + Triple Shot + Reflecting Tears) | AFTERBIRTH PLUS Gameplay | 1,106,364 | |
| 58. | TearofGrace | THE WARDEN (Triple Shot + Scythes + Lil' Delirium) | AFTERBIRTH PLUS Gameplay | 1,099,673 | |
| 59. | TearofGrace | The Binding of Isaac AFTERBIRTH: LUDOVICO + SPLIT SHOT + TRIPLE SHOT + SOY MILK | 1,083,892 | |
| 60. | TearofGrace | The Binding of Isaac REBIRTH: A Doomed Descent - THE NUCLEAR BASEMENT DEMON | 1,082,288 | |
| 61. | TearofGrace | THE ULTIMATE SPLIT SHOT SYNERGY: COLOBOMA MOD | AFTERBIRTH PLUS Gameplay | 1,067,525 | |
| 62. | TearofGrace | The Binding of Isaac: Afterbirth | TRIPLE-TRIPLE SHOT + MONSTRO'S LUNG + LUDOVICO (Mega Cain) | 1,060,915 | |
| 63. | TearofGrace | The Binding of Isaac REBIRTH: JUDAS IS BETRAYED BY HIS OWN LUCK | 1,053,428 | |
| 64. | TearofGrace | The Binding of Isaac AFTERBIRTH: THE LOST VS HUSH PT 2 - THE HUSHENING | 1,039,765 | |
| 65. | TearofGrace | The Binding of Isaac: Afterbirth | HOLY SHOT + GIANT SCYTHES + INCUBUS (Demon Angel) | 1,036,919 | |
| 66. | TearofGrace | MONSTRO'S LUNG + SCYTHES + IPECAC + HYDROPHOBICITY (Son of Lamb mod) | AFTERBIRTH PLUS Gameplay | 1,023,895 | |
| 67. | TearofGrace | TOG IN ISAAC? GLYPH OF BALANCE + SACRED HEART GAME BREAK | AFTERBIRTH PLUS Gameplay | 1,021,282 | |
| 68. | TearofGrace | The Binding of Isaac REBIRTH: BRIMSTONE + LUDOVICO TECHNIQUE (OP) | 1,020,821 | |
| 69. | TearofGrace | INFINITE TEARS SYNERGY (Parasite + Bone Tears + Fly Tears) | The Binding of Isaac: AFTERBIRTH PLUS | 1,001,100 | |
| 70. | TearofGrace | BOMB HURRICANE GAME BREAK (Sad Glitter Scatter MEGA Dr Fetus Bombs) | AFTERBIRTH PLUS Gameplay | 1,000,896 | |
| 71. | Game Maker's Toolkit | Secrets of Game Feel and Juice | 999,142 | |
| 72. | TearofGrace | MONSTRO'S LUNG + HUGE SCYTHES + DEAD EYE | The Binding of Isaac: Afterbirth Gameplay | 989,136 | |
| 73. | TearofGrace | ULTRA GREEDIER APOLLYON APOCALYPSE | The Binding of Isaac: AFTERBIRTH PLUS Gameplay | 987,933 | |
| 74. | TearofGrace | FIDGET SPINNER CHALLENGE (9 Shot + Monstro's Lung + Knife + Dr. Fetus) | AFTERBIRTH PLUS Gameplay | 985,818 | |
| 75. | TearofGrace | BANK SHOT MOD GAMEBREAK (Bouncing Split Shot + Soy Milk + Tech Zero) | AFTERBIRTH PLUS Gameplay | 985,814 | |
| 76. | TearofGrace | The Binding of Isaac REBIRTH: SUPER MEAT BOY VS. "SUPER" SATAN | 977,766 | |
| 77. | TearofGrace | The Binding of Isaac REBIRTH: DR FETUS + PURE EVIL | 972,226 | |
| 78. | TearofGrace | The Binding of Isaac REBIRTH: THE BLUE BABY LAWN MOWER | 968,705 | |
| 79. | TearofGrace | The Binding of Isaac REBIRTH: THE SHIELDED TEAR OF DOOM | 963,577 | |
| 80. | TearofGrace | The Binding of Isaac: Afterbirth | TRIPLE SHOT + SUPER SCYTHES + GUPPY | 942,387 | |
| 81. | TearofGrace | The Binding of Isaac AFTERBIRTH: DOCTOR FETUS + TECH X + DOUBLE SHOT | 935,287 | |
| 82. | TearofGrace | The Binding of Isaac REBIRTH: BRIMSTONE + TAMMY'S HEAD + GUPPY | 927,364 | |
| 83. | TearofGrace | JACOB & ESAU (CONTROLLED TEARS + SPLASH DAMAGE) | The Binding of Isaac ANTIBIRTH Gameplay | 914,957 | |
| 84. | JackEdit | Jerma's INSANE Binding of Isaac Build | 912,039 | |
| 85. | TearofGrace | The Binding of Isaac AFTERBIRTH: THE GUARDIAN OF THE GLUTTON | 880,399 | |
| 86. | TearofGrace | ISAAC'S ISAACS - The Best Dumbest Mod Ever | AFTERBIRTH PLUS Gameplay | 875,842 | |
| 87. | TearofGrace | The Binding of Isaac REBIRTH: MOM'S KNIFE + SPOON BENDER (OP) | 872,951 | |
| 88. | TearofGrace | WHOLE NEW TEAR STYLE VS DELIRIUM (Nemesis Mod) | AFTERBIRTH PLUS Gameplay | 867,313 | |
| 89. | TearofGrace | The Binding of Isaac REBIRTH: IPECAC ISAAC VS MEGA SATAN | 854,313 | |
| 90. | TearofGrace | The Binding of Isaac REBIRTH: THE PINKING SHEARS OF DOOM | 854,300 | |
| 91. | TearofGrace | The Binding of Isaac REBIRTH: MEGA DEATH VS BLUE BABY | 854,299 | |
| 92. | TearofGrace | BRIMSTONE KNIFE BOMB GAME BREAKING SYNERGY (Vortex Orb Mod) | AFTERBIRTH PLUS Gameplay | 853,545 | |
| 93. | TearofGrace | IPE-TIC-TAC-TOE CHALLENGE (Broken Build) | AFTERBIRTH PLUS Gameplay | 824,927 | |
| 94. | TearofGrace | The Binding of Isaac REBIRTH: JUDAS SLAYS THE ANTI-CHRIST | 821,457 | |
| 95. | TearofGrace | MISSINGNO CHALLENGE (Tech Everything) | The Binding of Isaac: Afterbirth Gameplay | 815,902 | |
| 96. | TearofGrace | The Binding of Isaac AFTERBIRTH: THE KEEPER MEETS HIS INNER DEMON | 814,614 | |
| 97. | TearofGrace | The Binding of Isaac REBIRTH: PSYCHIC BRIMSTONE ARMAGEDDON | 814,379 | |
| 98. | TearofGrace | The Binding of Isaac AFTERBIRTH: THE KEEPER'S KARMA (PG as Nobs) | 813,135 | |
| 99. | TearofGrace | The Binding of Isaac REBIRTH: THE BACKWARD LAZER DEMON SEED | 809,162 | |
| 100. | TearofGrace | ONE PUNCH MAN GONE WRONG | AFTERBIRTH PLUS | 807,233 | |
