| 1. |  WRELOW | Binding of Isaac - How to kill Mega Satan with The Lost (foolproof) | 9,196 | Tutorial |
| 2. | Twisted - HoneyBunnyGames | Knife Piece Puzzles - The Binding of Isaac: ANTIBIRTH - Part 2 [Let's Play Antibirth] | 6,513 | Let's Play |
| 3. | Twisted - HoneyBunnyGames | Free Fan Made Expansion! - The Binding of Isaac: ANTIBIRTH - Part 1 [Let's Play Antibirth] | 1,671 | Let's Play |
| 4. | Twisted - HoneyBunnyGames | Knife God - The Binding of Isaac: AFTERBIRTH+ - Episode 1 [Let's Play Afterbirth +] | 574 | Let's Play |
| 5. | The Djubre | The Binding of Isaac: Rebirth Ep1 |The Djubre| | 520 | |
| 6. | WRELOW | HOW I GOT INFINITE DEATH CERTIFICATE WITH TAINTED CAIN (EPIC MONTAGE) | 510 | |
| 7. | VEXXEDGAMING | Call of Commander : Zombie Island by Magic Cube/ IOS & Google Play Store / Gameplay Video | 509 | |
| 8. | VEXXEDGAMING | Kingdom Rush Vengeance - Game for both iphone and ipad - Game review | 502 | Review |
| 9. | The Djubre | The Djubre igra Binding of Isaac: Rebirth Ep2 | 365 | |
| 10. | WRELOW | Isaac: Repentance - 45# DELETE THIS | 6:14 IGT WILDEST AND LUCKIEST CHALLENGE SPEEDRUN | 365 | |
| 11. | Twisted - HoneyBunnyGames | Fire & Ice - The Binding of Isaac: ANTIBIRTH - Part 3 [Let's Play Antibirth] | 362 | Let's Play |
| 12. | VEXXEDGAMING | Tower Defense® HD By Com2uS USA, Inc.( IPad ) Gameplay | 345 | |
| 13. | Twisted - HoneyBunnyGames | Apollyon - The Binding of Isaac: AFTERBIRTH+ - Episode 2 [Let's Play Afterbirth +] | 344 | Let's Play |
| 14. | Twisted - HoneyBunnyGames | The Pong Challenge - The Binding of Isaac: AFTERBIRTH+ - Episode 3 [Let's Play Afterbirth +] | 270 | Let's Play |
| 15. | VEXXEDGAMING | Burn It Down by Tapinator,LLC
[ IOS Game Trailer ] | 269 | |
| 16. | Twisted - HoneyBunnyGames | REROLL! - The Binding of Isaac: AFTERBIRTH+ - Episode 4 [Let's Play Afterbirth +] | 227 | Let's Play |
| 17. | WRELOW | Binding of Isaac - How to kill Mega Satan with The Keeper (any setup) | 212 | |
| 18. | WRELOW | July 16th 2021 Binding of Isaac Daily Run [Montage] DIDN'T GET MARATHON | 92 | |
| 19. | WRELOW | Tainted Lost Greedier Sacred H. Godhead and D20 GAMEBREAK | 59 | |
| 20. | WRELOW | Binding of Isaac - EPIC Azazel Godhead Mega Satan | 48 | |
| 21. | WRELOW | BOI: Challenge #29 Onan's Streak - The Convenient Way | 43 | |
| 22. | WRELOW | July 17th 2021 Binding of Isaac Daily Run [Montage] | 42 | |
| 23. | Markoode | The Binding of Isaac - Rebirth | MakiGames | 42 | |
| 24. | VEXXEDGAMING | Bugsnax - Epic Games - Game Review | 41 | Review |
| 25. | WRELOW | Isaac - DON'T DO A DAILY RUN/CHALLENGE ON SUNDAY July 11th 2021 [Fast Montage] | 30 | |
| 26. | Glassy | Repentance is fun | 30 | |
| 27. | MATT PLAYS | The Binding of Isaac Repentance: Ending and Final Boss Fight! | 23 | |
| 28. | WRELOW | July 13th 2021 Binding of Isaac Daily Run [Montage] | 20 | |
| 29. | WRELOW | Tainted Keeper v Mother - RED KEY AND KEEPER'S SACK | 18 | |
| 30. | WRELOW | Isaac - Keeper trippin | 11 | |
| 31. | WRELOW | Cain Hush fast montage and 1001% cleanup (Eden trick) | 11 | |
| 32. | WRELOW | if a friend asks you what Binding of Isaac is you show him this clip | 11 | |
| 33. | Tilter | The Daily binding of Isaac: AFTERBIRTH #1 | 7 | |
| 34. | Tilter | The binding of Isaac: AFTERBIRTH #1 | 6 | |
| 35. | WRELOW | Binding of Isaac - EPIC Eve Mega Satan D4 Roll | 5 | |
| 36. | WRELOW | T. Judas Lamb done - 9 characters to go | 5 | |
| 37. | WRELOW | Tainted Lost v Beast - Infallible tactic | 5 | |
| 38. | WRELOW | Binding of Isaac: Afterbirth Killer RNG | 5 | |
| 39. | WRELOW | This game is obnoxious - T. Jacob Beast | 5 | |
| 40. | WRELOW | TRUE ONAN'S STREAK (i fucked it up) | 5 | |
| 41. | WRELOW | Tainted Jacob v Beast - It's a sticky situation | 4 | |
