| 1. |  Ujary | Can I Complete EVERY Tainted Lost Checkmark in ONE Sitting? | 291,724 | |
| 2. | Ujary | Jerma following my instructions with absolutely zero hesitation | 160,116 | |
| 3. | Ujary | Binding of Isaac ENEMY RANDOMIZER, But I Take a Shot Every Death | 68,501 | |
| 4. | Ujary | Tainted Lost VS TMTRAINER | 54,306 | |
| 5. | Ujary | Can I Beat Tainted Lost Without Shooting? | 36,231 | |
| 6. | Ujary | I Streamed Until I Beat EVERY Tainted Jacob Checkmark (EDITED) | 29,027 | Tutorial |
| 7. | Ujary | T. Lost VS TMTRAINER, But I Take a SHOT Every Death (10K SUB SPECIAL) | 26,402 | |
| 8. | Spits | The Binding of Isaac: Rebirth - The Lamb Bossfight & Ending (World first?) | 23,033 | |
| 9. | Ujary | Spreading Alcoholism to the Isaac Community (Ft. AnotherMatt) | 19,899 | |
| 10. | Ujary | "Maybe we get sigil" | 19,166 | |
| 11. | Ujary | Tainted Lost VS TMTRAINER - But I take a SHOT Every Death (Again) | 18,126 | |
| 12. | Ujary | Every Item Buff in the New Coop Update | 16,383 | |
| 13. | Ujary | Isaac, But I Can't Shoot | 16,235 | |
| 14. | Ujary | Every hit, all enemies are doubled | 15,345 | |
| 15. | Ujary | Tainted Lost, But Every Room gets Crooked Penny'd | 8,998 | |
| 16. | Spits | 10 Second Mega Satan Fight | 5,768 | |
| 17. | Ujary | Isaac, But I Start With The Thief Familiars | 5,071 | |
| 18. | Spits | The Binding of Isaac: Rebirth - Final Boss - Mega Satan & Ending | 4,400 | |
| 19. | VoicesFromTheDark | Dark Plays: The Binding of Isaac: Rebirth [01] - "Laser Pageant Boy" | 3,886 | Let's Play |
| 20. | Ujary | Isaac, But Every 30 Seconds the Character Changes | 3,476 | |
| 21. | Ujary | I Slept Through the Delirium Fight👍 | 3,424 | |
| 22. | Ujary | He got his answer😭 #shorts | 2,356 | |
| 23. | Ujary | Every Room Clear Spawns an Esau | 2,178 | |
| 24. | Ujary | Tainted Jacob's Hidden Mechanic | #shorts | 2,085 | |
| 25. | Spits | Negative Damage IPECAC | 2,074 | |
| 26. | VoicesFromTheDark | Dark Plays: The Binding of Isaac: Rebirth [02] - "Swagboy McFly" | 1,592 | Let's Play |
| 27. | Ujary | 🔴 T.Lost TMTRAINER, But I Take a SHOT Every Death (10K SUB SPECIAL) | 1,531 | |
| 28. | Ujary | Tainted Lost VS TMTRAINER, But I Take a SHOT Every Death (Finale) [Livestream] | 1,467 | |
| 29. | Torpington | The Binding of Isaac: Afterbirth [1][Let's Play] | 1,394 | Let's Play |
| 30. | VoicesFromTheDark | Dark Plays: The Binding of Isaac: Rebirth [03] - "Ballsack Satan" | 1,379 | Let's Play |
| 31. | VoicesFromTheDark | Dark Plays: The Binding of Isaac: Rebirth [05] - "Devil Dealer" | 1,379 | Let's Play |
| 32. | VoicesFromTheDark | Dark Plays: The Binding of Isaac: Rebirth [04] - "Puberty Girl" | 1,346 | Let's Play |
| 33. | VoicesFromTheDark | Dark Plays: The Binding of Isaac: Rebirth [07] - "Mom Fight" | 1,337 | Let's Play |
| 34. | VoicesFromTheDark | Dark Plays: The Binding of Isaac: Rebirth [06] - "Azazel" | 1,276 | Let's Play |
| 35. | Ujary | Isaac, but every 30 seconds the character changes (livestream) | 1,244 | |
| 36. | VoicesFromTheDark | Dark Plays: The Binding of Isaac: Rebirth [08] - "Furry Demon" | 1,102 | Let's Play |
| 37. | VoicesFromTheDark | Dark Plays: The Binding of Isaac: Rebirth [09] - "Sticky Cultist" | 1,035 | Let's Play |
| 38. | VoicesFromTheDark | Dark Plays: The Binding of Isaac: Rebirth [10] - "Grumpfest 2015" | 1,010 | Let's Play |
| 39. | Torpington | The Binding of Isaac: Rebirth [41][Let's Play] | 933 | Let's Play |
| 40. | VoicesFromTheDark | Dark Plays: The Binding of Isaac: Rebirth [13] - "The Joker" | 926 | Let's Play |
| 41. | Spits | Rebirth - Dad's Key Opens The Golden Door to Mega Satan | 918 | |
| 42. | VoicesFromTheDark | Dark Plays: The Binding of Isaac: Rebirth [15] - "Sheol" | 896 | Let's Play |
| 43. | VoicesFromTheDark | Dark Plays: The Binding of Isaac: Rebirth [14] - "Magnet Boy" | 876 | Let's Play |
| 44. | VoicesFromTheDark | Dark Plays: The Binding of Isaac: Rebirth [12] - "Maggie Moo" | 872 | Let's Play |
| 45. | Ujary | Can I win as Tainted Lost without shooting? | 837 | |
| 46. | VoicesFromTheDark | Dark Plays: The Binding of Isaac: Rebirth [11] - "Three Ballz" | 835 | Let's Play |
| 47. | Torpington | The Binding of Isaac: Rebirth [38][Let's Play] | 763 | Let's Play |
| 48. | Torpington | The Binding of Isaac: Rebirth [40][Let's Play] | 757 | Let's Play |
| 49. | Ujary | 🔴 isaac gaming (holy hell) (File 2) | 646 | |
| 50. | Torpington | THE LOST DRINKING GAME? - The Binding of Isaac: Rebirth [1][Drunk Gaming] | 506 | |
| 51. | Torpington | The Binding of Isaac: Rebirth [37][Let's Play] | 435 | Let's Play |
| 52. | GachaPenguin | Penguinette’s Bow | Tried my best for a girl voice -w- | GachaPenguin Shorts | 425 | |
| 53. | Spits | The Binding of Isaac: Rebirth - It Lives, Satan & The Lamb Kills | 385 | |
| 54. | Torpington | The Binding of Isaac: Rebirth [33][Let's Play] | 354 | Let's Play |
| 55. | Torpington | The Binding of Isaac: Rebirth [35][Let's Play] | 352 | Let's Play |
| 56. | Tritonex | The Binding of Isaac: Rebirth PS Vita HD Gameplay (Vita3K) | 352 | |
| 57. | Torpington | The Binding of Isaac: Rebirth [30][Let's Play] | 336 | Let's Play |
| 58. | Torpington | FAILING AT THE LOST - The Binding of Isaac: Rebirth [5][Extra][Let's Play] | 326 | Let's Play |
| 59. | Torpington | The Binding of Isaac: Rebirth [31][Let's Play] | 318 | Let's Play |
| 60. | Torpington | The Binding of Isaac: Rebirth [28][Let's Play] | 316 | Let's Play |
| 61. | Spits | Rebirth Synergies - Tammy's Head, Death's Touch, Cricket's Body | 312 | |
| 62. | Torpington | The Binding of Isaac: Rebirth [39][Let's Play] | 308 | Let's Play |
| 63. | Torpington | The Binding of Isaac: Rebirth [36][Let's Play] | 277 | Let's Play |
| 64. | Torpington | The Binding of Isaac: Rebirth [29][Let's Play] | 269 | Let's Play |
| 65. | Torpington | The Binding of Isaac: Rebirth [34][Let's Play] | 245 | Let's Play |
| 66. | Torpington | The Binding of Isaac: Rebirth [32][Let's Play] | 212 | Let's Play |
| 67. | TheDragonFruit | The Binding Of Isaac Rebirth | Episode 1 | 99 Bombs but a Key ain't One | 200 | |
| 68. | Doschy | The Worst Isaac Video You Will Ever See 💀 | 194 | |
| 69. | Ujary | Full video on this channel! #shorts #thebindingofisaac #taintedlost | 192 | |
| 70. | GachaPenguin | The Hypnotist hypnotizes Penguinette (RP) | 182 | |
| 71. | Torpington | The Binding of Isaac: Afterbirth [2][Let's Play] | 172 | Let's Play |
| 72. | GachaPenguin | Imagine Penguin getting hypnotized by K- (Don’t say the name, okay) *sigh* Fine! (RP) | 168 | |
| 73. | Doschy | I will become back my money - BS Isaac Deaths | 163 | |
| 74. | GachaPenguin | ... | 150 | |
| 75. | GachaPenguin | Now I just need 500? | 146 | |
| 76. | Hanniballshow | 🔴 Going in blind (Binding of Isaac) From the Livestream - May 12 2017 | 120 | |
| 77. | GachaPenguin | Penguin as “It lives” from TBOI: Rebirth | 120 | |
| 78. | Doschy | Isaac Music Sync Practice | 115 | |
| 79. | Spits | The Binding of Isaac: Rebirth - Dark Room clear - Most Powerful Run | 112 | |
| 80. | GachaPenguin | Penguin as a Delirium transformation | 101 | |
| 81. | Lulucy Mery | [The binding of Isaac] ARRRRRR THIS TIME I WILL DO IT!! | 95 | |
| 82. | Torpington | The Binding of Isaac: Rebirth [26][Let's Play] | 76 | Let's Play |
| 83. | GachaPenguin | So... I used rave.dj to make a mashup... | Crusade Dispersio | TBOI Rebirth/Afterbirth Mashup | 75 | |
| 84. | Torpington | The Binding of Isaac: Afterbirth [3][Let's Play] | 60 | Let's Play |
| 85. | Lulucy Mery | [The binding of Isaac] We will do it again! | 59 | |
| 86. | Torpington | The Binding of Isaac: Rebirth [#1][Let's Play] | 56 | Let's Play |
| 87. | GachaPenguin | My first Angel Room Encounter (The Binding of Isaac: Afterbirth+) | 54 | |
| 88. | Nora the Antipaladin | Binding of Isaac Rebirth: Instagib Isaac | 54 | |
| 89. | Cryptical Void | Binding of Isaac: Afterbirth - #1. Mega Fatty! | 53 | |
| 90. | GachaPenguin | The Binding of Isaac art I drew! | 50 | |
| 91. | Spits | Rebirth Synergies Brimtone + Anti Gravity Tears | 43 | |
| 92. | Guiwenneth | The Binding of Isaac Rebirth - ??? (boss) (#1) 60fps | 33 | |
| 93. | Spits | Rebirth Synergies: What even is this mess | 31 | |
| 94. | Cryptical Void | Binding of Isaac: Afterbirth - #2:1. Splash Damage Er Konge! | 27 | |
| 95. | Styleth | GSQD PODCAST - Første podcast, det merkes.. | 27 | Show |
| 96. | Failer Gamer | The Binding Of Mario Custom run modded! | 26 | |
| 97. | Torpington | The Binding of Isaac: Afterbirth [4][Let's Play] | 25 | Let's Play |
| 98. | Not Rivals | This is what Trisagion+Ipecac used to look like | 24 | |
| 99. | Torpington | Rogue Legacy [Let's Try] | 23 | |
| 100. | Keymahan | Binding of Isaac Rebirth [X1] ep: 1 Eden Quad Start | 23 | |
