| 1. |  Kikoskia | 3,928,665 | OpenXCOM VOD #14 (29/01/20): BOOM and the Alien’s Gone | 2:11:03 |
| 2. | The Yogscast | 1,344,724 | Yogscast - X-Com: UFO Defence Part 3 - Captain Jungo | 20:28 |
| 3. | Yogscast Live | 485,234 | The Final Fight! - XCOM UFO Defense w/ Lewis & Ben - 13th March 2016 | 3:20:53 |
| 4. | Lewis and Ben Save the World | 383,626 | The XCOM Files #73 - It's a Disaster | 2:48:07 |
| 5. | ArchmageMelek | 178,978 | X-COM (1994) Superhuman Ironman - Part 7 | 21:54 |
| 6. | Lomadiah | 65,599 | YogTrailers - X-Com E3 Trailer | 2:15 |
| 7. | Eurogamer | 54,555 | The original X-COM was cancelled, but development continued in secret - Here's A Thing | 8:30 |
| 8. | Stylosa | 39,501 | Open Xcom - X-Com: UFO Defense in 1080p! | 15:40 |
| 9. | Nemonaemo | 24,582 | Nemo Plays: OpenXCOM 40k #63 - It's Going To Be A Terminator Base | 30:58 |
| 10. | TheGamakazi | 21,494 | Let's Play The X-COM Files: Part 312 Tank Through The Roof! | 28:37 |
| 11. | The Beardy Penguin | 17,315 | Final Assault | XCOM: UFO Defense | 1:54:43 |
| 12. | Shadowhawk | 12,051 | -01- Open X-com: UFO Defence - Pacifist Challenge | 1:59:50 |
| 13. | Hex DSL | 7,492 | openXcom - Its old X-Com but new. | 13:59 |
| 14. | Trauson | 6,172 | X Com Ufo Defense Gameplay : Defender la base con vuestra vida | 46:30 |
| 15. | zxspectrumgames4 | 5,978 | U.F.O. Enemy Unknown -- showing various terrain types (ZX Spectrum) | 41:06 |
| 16. | RMC - The Cave | 5,243 | X-COM UFO Defense Music | Roland SC-88 | 1:33 |
| 17. | Ogiwon TV | 3,526 | E192 X-Com Files: Chtonite First Contact on 06 March 2000 Gameplay | 18:08 |
| 18. | YOGSCAST Best Bits Weekly | 2,359 | Lewis and Ben Save The World Stream Highlights - A HARPOON! | 4:51 |
| 19. | IkiFoo | 2,147 | Let's Play X-COM: UFO Defense (FINALE) | 35:17 |
| 20. | 101DTBroadcastGaming | 1,646 | CYDONIA! - OpenXcom Superhuman Ironman Challenge #17 (FINAL) | 45:48 |
| 21. | Laurence Plays | 1,353 | Classic X-COM - Laurence Streams | 5:00:04 |
| 22. | UnstableVoltage | 1,332 | Xenonauts - Mechanic differences with X-Com: UFO Defense (UFO: Enemy Unknown) | 37:01 |
| 23. | MxTeoes | 1,295 | Rematch: X-Com vs. Cyberdiscs (UFO: Enemy Unknown w/ Yeti, Part 24) | 31:26 |
| 24. | Lord Daveed | 1,097 | Lets Play X-COM UFO Defense - Part 73 THE KNIGHTS OF CYDONIA! (Finale) | 59:21 |
| 25. | TheShadowscythe | 1,059 | OpenXcom - Final Mod Pack - Episode 19 | 30:59 |
| 26. | GameWatcher | 673 | Most Played UFO / XCOM Games | 4:20 |
| 27. | Fruity Spruce | 594 | Fruity Looks at Files - Incident 002 | 25:58 |
| 28. | Jack De Hearts | 556 | Can I beat X-Com UFO Defense with just the Pistol? | 4:18:24 |
| 29. | Timberwolf | 529 | X-COM: The Wilderness Years | 10:24 |
| 30. | XTRG | 479 | And It Begins Xcom UFO Defense Episode 4 - Game Crash | 17:23 |
| 31. | Game on Drone on | 386 | UFO: Defense ( forgot aliens can prime grenades for 0 timer lmao) | 1:34:05 |
| 32. | Balious | 297 | Let's Stream X-COM: UFO Defense - Part 5 - 14/07/2018 | 2:44:49 |
| 33. | legodude494 | 218 | Retro Weekend! - XCOM UFO Defence with the OpenXcom mod: part 15 | 21:23 |
| 34. | TheEdmon | 190 | XCOM: You Should Have Played It | 33:31 |
| 35. | GordonFBR | 181 | Cydonia - X-COM: UFO Defense Final Mod Pack [Part 32] - Twitch VODs | 1:57:54 |
| 36. | Nuke4Prez | 133 | THE ORIGINAL XCOM (With A Twist) - OpenXCOM (XCOM: UFO Defense/ UFO: Enemy Unknown Gameplay) | 54:53 |
| 37. | BurntTNTFreak | 119 | Xcom: UFO Defence! - Episode 5 | 30:43 |
| 38. | 9EG | 94 | MY TOP 5 FAVORITE AMIGA CD32 GAMES | 5:51 |
| 39. | Heiach | 80 | Let's Try XCOM: UFO Defence (OpenXcom) - Welcome To XCOM! | 14:19 |
| 40. | EnchaJini | 39 | DOS Days: Retro Fun - XCOM UFO Defense 2# | 16:53 |
| 41. | Wild Psyduck | 38 | XCOM: UFO Enemy Unknown on Roland SC-8820 | 53:54 |
| 42. | Caldaris | 38 | OpenXcom - Skirmishes | 44:53 |
| 43. | LuckyFandango | 26 | So, many, Chryssalid's... - X-Com: UFO Defence (3) | 3:26:30 |
| 44. | King Toko | 26 | UFO: Enemy Unknown (DOS) - Good Game #109 | 40:32 |
| 45. | Michael Disley | 17 | UFO: Enemy Unknown | 63 | Males in Jet | 31:02 |
| 46. | IkiFoo dot TV | 16 | X-COM Enemy UFO Unknown Defense (OpenXCOM) | 5:34:27 |
| 47. | Through Retro Tinted Glasses | 12 | Title screen : X-COM: UFO Defense : PS1 #Shorts | 0:59 |
| 48. | fireballstardraco | 12 | X Com part 2 I forgot how hard you were | 1:27:39 |
| 49. | Kohigh Mathy | 11 | Kohigh Mathy's VEDA 2021 | Day Twenty Four | 1:31 |
| 50. | Nonsuch Games | 11 | Just One Look. UFO : Enemy Unknown (X-COM) | 16:10 |
| 51. | Kerr9000 | 10 | Gaming Memories from my Childhood | 3:06 |
| 52. | Mason Ap Archive | 7 | MaceCOM is losing the war... Join us anyway! XCOM UFO Defence Part 5 | 4:22:22 |
| 53. | Haydock83 | 2 | X COM UFO Defense | 1:31 |
| 54. | GobrinSan | 1 | X-Com UFO Defence, Old School | 1:06:44 |
