2'-Hydroxyisoflavone reductase

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Published on August 17, 2021 9:00:55 PM ● Video Link: https://www.youtube.com/watch?v=X5jraJ98yE4

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In enzymology, a 2'-hydroxyisoflavone reductase (EC 1.3.1.45) is an enzyme that catalyzes the chemical reaction

vestitone + NADP+



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{\displaystyle \rightleftharpoons }
2'-hydroxyformononetin + NADPH + H+Thus, the two substrates of this enzyme are vestitone and NADP+, whereas its 3 products are 2'-hydroxyformononetin, NADPH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is vestitone:NADP+ oxidoreductase. Other names in common use include NADPH:2'-hydroxyisoflavone oxidoreductase, isoflavone reductase, and 2',7-dihydroxy-4',5'-methylenedioxyisoflavone reductase.

Source: https://en.wikipedia.org/wiki/2%27-Hydroxyisoflavone_reductase
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