Dead Space 2 - Where Am I (Chapter #1)
Isaac is seen being questioned about the events that transpired on the USG Ishimura three years ago on a space station called The Sprawl. Upon being questioned, Isaac suddenly saw the visions of his dead girlfriend, Nicole and many of the other monstrosities that he saw aboard the Ishimura in Dead Space which causes him to black out. Isaac wakes up an unknown amount of time later to be informed by Franco, the protagonist of Dead Space: Ignition that he is in 'grave danger'. Franco was killed by an Infector, turning him into a Slasher. After making his way through the hospital section of The Sprawl and witnessing many of the horrors of the Necromorph attack, Isaac is contacted by Daina who informs Isaac that they need to meet because the dementia that he developed on Aegis VII will kill him.