Penny Sanchez invents the Animal Serum. She drinks it along with The Powerpuff Girls, Wendy Testaburger, Mandy, Jessicake, Star Butterfly, Pucca, Trixie Tang, June and Annie. Soon, They have become animals. Blossom is a walrus, Bubbles is a bee, Buttercup is a flamingo, Wendy Testaburger is a pufferfish, Mandy is a frog, Jessicake is an elephant, Star Butterfly is a cat, Pucca is a panda, Trixie Tang is a bird, June is a mouse, Annie is a monkey and Penny Sanchez is a mole. Jenny Wakeman (XJ9) found out what has happened. She realizes that the Animal Serum was the potion for all the animals. The Next Day, the Animal Girls do whatever they wanted. Later, Jenny has found the cure for the antidote. It will make turn the animals back into humans. The Other Girls are now cured. Penny was so happy and hugs Jenny Wakeman. Star Butterfly wants her to become a human like the Other Girls. Now Jenny Wakeman is a most beautiful human in the world. Penny Sanchez wanted her to go to the park. Mandy eats the camera as she screams in the end.