Molar pregnancy
0Molar pregnancy, by Wikipedia https://en.wikipedia.org/wiki?curid=1010250 / CC BY SA 3.0
#Germ_cell_neoplasia
#Pregnancy_with_abortive_outcome
Molar pregnancy is an abnormal form of pregnancy in which a non-viable fertilized egg implants in the uterus and will fail to come to term.
A molar pregnancy is a gestational trophoblastic disease which grows into a mass in the uterus that has swollen chorionic villi.
These villi grow in clusters that resemble grapes.
A molar pregnancy can develop when a fertilized egg does not contain an original maternal nucleus.
The products of conception may or may not contain fetal tissue.
It is characterized by the presence of a hydatidiform mole （or hydatid mole, mola hydatidosa）.
Molar pregnancies are categorized as partial moles or complete moles, with the word mole being used to denote simply a clump of growing tissue, or a growth.
A complete mole is caused by a single sperm （90% of the time） or two （10% of the time） sperm combining with an egg which has lost its DNA. In the first case, the sperm then reduplicates, forming a "complete" 46 chromosome set.
The genotype is typically 46,XX （diploid） due to the subsequent mitosis of the fertilizing sperm but can also be 46,XY （diploid）.
46,YY （diploid） is not observed.
In contrast, a partial mole occurs when a normal egg is fertilized by one or two sperm which then reduplicates itself, yielding the genotypes of 69,XXY （triploid） or 92,XXXY （tetraploid）.
Complete hydatidiform moles have a 2–4% risk of developing into choriocarcinoma in Western countries and 10–15% in Eastern countries and a 15% risk of becoming an invasive mole.
Incomplete moles can become invasive （（5% risk） but are not associated with choriocarcinoma.
Complete hydatidiform moles account for 50% of all cases of choriocarcinoma.
Molar pregnancies are a relatively rare complication of pregnancy, making up 1 in 1,000 pregnancies in the US, with much higher rates in Asia （e.g. up to 1 in 100 pregnancies in Indonesia）.
Vesic...
Other Videos By all the knowledge of the universe PRINCIPIA
| 2022-01-20 | Paul Nicholls (horse racing) |
| 2022-01-20 | Durban Outer Ring Road |
| 2022-01-20 | MOMus–Museum of Modern Art–Costakis Collection |
| 2022-01-20 | Royal Victoria Infirmary |
| 2022-01-20 | Mainpuri |
| 2022-01-20 | Oak Ridge High School (El Dorado Hills, California) |
| 2022-01-20 | Steve Perry |
| 2022-01-20 | Goljak |
| 2022-01-20 | George Topîrceanu |
| 2022-01-20 | Frederick Weld |
| 2022-01-20 | Molar pregnancy |
| 2022-01-20 | Ilchi Lee |
| 2022-01-20 | Kings Weston House |
| 2022-01-20 | Masami Kobayashi |
| 2022-01-20 | Mallee Cliffs National Park |
| 2022-01-20 | Crate |
| 2022-01-20 | Balls to Picasso |
| 2022-01-20 | The Canadian Crown and the Canadian Armed Forces |
| 2022-01-20 | Selichot |
| 2022-01-20 | Lane Cove National Park |
| 2022-01-20 | William Alabaster |