QX39
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0QX39 (Compound A, CA39) is a synthetic compound that activates chaperone-mediated autophagy (CMA) by increasing the expression of the lysosomal receptor for this pathway, LAMP2A lysosomes. It showed potent activity in vitro but has poor pharmacokinetic properties and was not suitable for animal research. Subsequent research led to the development of CA77.1, a CMA activator suitable for in vivo use.
== References ==
Source: https://en.wikipedia.org/wiki/QX39
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Tags:
CA771
CASRegistryNumber
Chaperonemediatedautophagy
Chemicalformula
Doiidentifier
IUPACnomenclatureofchemistry
InternationalChemicalIdentifier
JSmol