Seth Feroce Site Enhancement Misinformation | The Truth About Synthol And Hyaluronic Acid
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In order to make Hyaluronic Acid (HA) more durable, HA molecules are linked to one another. More cross-linking makes the HA molecules firmer in consistency, more water absorbent, and longer lasting. In other words, the more cross-linked and concentrated (mg/ml) the HA is, the thicker it will be, and the more water it will suck up/plump up whatever it is sitting in (skin, muscle, etc.). The more water it can suck up and the longer it can stay put without degradation, the more volumization/fascial stretching potential there would be.
An experienced clinician will choose the HA with right amount of cross-linking to meet your specific needs, based on the area(s) requiring treatment.
If the cross linking is very minimal it makes it a thin liquid, which is typically ideally suited for under-eye or tear trough fillers, whereas if the cross linking is much higher, it makes it a very thick gel, which is typically suited for bony areas of the face to enhance bony prominences like cheek bones, or site specific muscles in the body (like the buttocks) where it is administered intramuscularly to achieve maximum volumization/enlargement as it plumps up the most (absorbs the most water).
Stabilized hyaluronic acid gel for volume restoration and contouring of the buttocks: 24-month efficacy and safety: https://www.ncbi.nlm.nih.gov/pubmed/24464121
Comparison of noncross‐linked and cross‐linked hyaluronic acid with regard to efficacy of the proliferative activity of cutaneous fibroblasts and keratinocytes in vitro: https://www.ncbi.nlm.nih.gov/pubmed/23438140
A Multicenter, Single-Blind Randomized, Controlled Study of a Volumizing Hyaluronic Acid Filler for Midface Volume Deficit: Patient-Reported Outcomes at 2 Years: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482214/
Hyaluronic acid gel ( Juvéderm™) preparations in the treatment of facial wrinkles and folds: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2682392/
Comparative Physical Properties of Hyaluronic Acid Dermal
Fillers: http://www.clinicadepele.com.br/artigos/preenchimento/HA_group_comp.pdf
Hyaluronic Acid: Crosslinking And Degradation: https://www.iralab.it/en/publications/hyaluronic-acid-crosslinking-and-degradation/
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