Super Smash Bros. for Wii U: Offline: Carls493 (Mega Man) vs. aceman (Greninja)
In Mega Man context, Greninja is essentially what happens when you fuse the Robot Masters, Shadow Man & Toad Man, together. I'd even use this kickass Sega Genesis remix of Toad Man's theme as a custom theme for Greninja.
https://www.youtube.com/watch?v=tX9OOYc-xow
In Pokémon context, Mega Man's Electric Spark, Leaf Shield, Guts Arm, Hard Knuckle, and Mega Upper should all be Super Effective against Greninja, since Greninja is a Water/Dark type Pokémon. So Electric, Grass, and Fighting type moves should all wreck him pretty good.
Though with a tongue that long, Greninja's Lick move should make it an effective Ghost type, too.
Other Videos By Carls493
Other Statistics
Super Smash Bros. for Wii U Statistics For Carls493
Carls493 currently has 279,825 views spread across 1,251 videos for Super Smash Bros. for Wii U. His channel uploaded over 3 days worth of Super Smash Bros. for Wii U videos, roughly 3.39% of the content that Carls493 has uploaded to YouTube.