- "Maximum Security": the highest difficulty in the game available on release.
- New Game settings
- Hand Cannon playthrough: I use the Hand Cannon as the only gun. I still use the GRP and melee. The other guns aren't really necessary and going for other upgrades (mostly GRP) first pays off, you'll see it in the playthrough.
- All Collectibles: I collect all Implant Bios / Audio Logs. I visit all the optional areas, with one exception (Storage F816 - 2:05:30) that would most likely result in cheap damage from one enemy attacking right after a ladder and to be fair, there's nothing I could possibly loot there since I wouldn't have inventory space anyway.
- No Damage: no damage taken. A lot of grabs and interactions don't deal damage.
- Segmented per chapter walkthrough: I did each chapter in one segment.
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