Which of the following statements about Michaelis-Menten kinetics i...
Which of the following statements about Michaelis-Menten kinetics is correct?
I. A high Michaelis constant \( \left(\mathrm{K}_{\mathrm{m}}\right) \) indicates a high affinity of an enzyme for its substrate.
II. A low Michaelis constant \( \left(K_{m}\right) \) indicates a high affinity of an enzyme for its substrate.
III. The Michaelis constant \( \left(\mathrm{K}_{\mathrm{m}}\right) \) of an enzyme increases when the enzyme concentration is increased.
\( \mathrm{P} \)
IV. The Michaelis constant \( \left(K_{m}\right) \) of an enzyme is unchanged when the enzyme concentration is increased.
(a) I and II are correct
(b) II and III are correct
(c) II and IV are correct
(d) I and III are correct
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