Top 100 The Binding of Isaac: Rebirth Videos With The Most Comments by Sam HuangTop 100 » 200 » 300 » 400 » 500Video TitleCommentsCategoryGame1.Quick Examination of Lilith! | The Binding of Isaac: Afterbirth (Pt. 4)6The Binding of Isaac: Rebirth 2."Beans!" Challenge is NOT Fun... | The Binding of Isaac: Antibirth5The Binding of Isaac: Rebirth 3.First Try Greedier! | The Binding of Isaac Afterbirth+4The Binding of Isaac: Rebirth 4.MEGA SATAN BEATEN! | The Binding of Isaac: Afterbirth+3The Binding of Isaac: Rebirth 5.KEEPER IS PAIN!!! | The Binding of Isaac: Afterbirth+2The Binding of Isaac: Rebirth 6.GREEDIER! | The Binding of Isaac: Afterbirth+2The Binding of Isaac: Rebirth 7.Successful daily run! | The Binding of Isaac: Afterbirth+2The Binding of Isaac: Rebirth 8.TBOI: Full Keeper Run (This is why keeper sux lol)2The Binding of Isaac: Rebirth 9.GETTING THE D6! | The Binding of Isaac: Afterbirth+2The Binding of Isaac: Rebirth 10.Isaac and the Satanic Bible! | The binding of Isaac: Afterbirth (Pt. 3)2The Binding of Isaac: Rebirth 11.TFW Being Rusty | The Binding of Isaac: Repentance2The Binding of Isaac: Rebirth 12.APOLLYON! | The Binding of Isaac: Afterbirth+1The Binding of Isaac: Rebirth 13.Isaac Greedier! | The Binding of Isaac: Afterbirth+1The Binding of Isaac: Rebirth 14.AFTERBIRTH!!!??? | The Binding of Isaac: Afterbirth (Pt. 1)1The Binding of Isaac: Rebirth 15.Binding of Isaac Repentance But It's TAINTED JACOB1The Binding of Isaac: Rebirth 16.Challenges: Computer Savvy | Binding of Isaac: Rebirth (Pt. 3)1The Binding of Isaac: Rebirth 17.PS4 Controller and the Lost | The Binding of Isaac: Afterbirth+0The Binding of Isaac: Rebirth 18.Isaac Afterbirth+ is "EZ"0The Binding of Isaac: Rebirth 19.DEFEATED SATAN! | The Binding of Isaac: Afterbirth (Pt. 2)0The Binding of Isaac: Rebirth 20.Most OP Azazel Run!0The Binding of Isaac: Rebirth 21.Keeper Vs Delirium! (The Hardest Task I Had to Complete) | The Binding of Isaac: Afterbirth+0The Binding of Isaac: Rebirth 22.Sometimes Isaac Isn't Always On Your Side...0The Binding of Isaac: Rebirth 23.Cain Vs Witness! | The Binding of Isaac: Antibirth0The Binding of Isaac: Rebirth 24.Is it really that Hard? | Binding of Isaac: Rebirth (Pt. 1)0The Binding of Isaac: Rebirth 25.Witness is HARD! | The Binding of Isaac: Antibirth0The Binding of Isaac: Rebirth 26.First Daily Run! | The Binding of Isaac: Afterbirth (Pt. 5)0The Binding of Isaac: Rebirth 27.Lilith can be a pain in the butt sometimes...0The Binding of Isaac: Rebirth 28.Binding of Isaac Repentance Stream!0The Binding of Isaac: Rebirth 29.TAINTED LOST IS HARD [TBOI]0The Binding of Isaac: Rebirth Top 100 » 200 » 300 » 400 » 500