| 401. | Giant | The Binding of Isaac: Repentance | 1,324 | | The Binding of Isaac: Rebirth
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| 402. | This used to CRASH the game | The Binding of Isaac: Repentance | 1,324 | | The Binding of Isaac: Rebirth
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| 403. | One Hit | The Binding of Isaac: Repentance | 1,323 | | The Binding of Isaac: Rebirth
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| 404. | Don't get too close to me | The Binding of Isaac: Repentance | 1,323 | | The Binding of Isaac: Rebirth
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| 405. | Is this the SUPERIOR HEART for Greedier? | The Binding of Isaac: Repentance | 1,322 | | The Binding of Isaac: Rebirth
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| 406. | Everyone gets an Aura! | 1,322 | | The Binding of Isaac: Rebirth
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| 407. | I tried out BUFFED MARS so you don't have to | The Binding of Isaac: Repentance | 1,319 | | The Binding of Isaac: Rebirth
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| 408. | FOUR Times the STEW | The Binding of Isaac: Repentance | 1,315 | | The Binding of Isaac: Rebirth
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| 409. | Black Ring of DESTRUCTION | The Binding of Isaac: Repentance | 1,315 | | The Binding of Isaac: Rebirth
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| 410. | Ketchup Ring | The Binding of Isaac: Repentance | 1,315 | | The Binding of Isaac: Rebirth
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| 411. | I brought my Pet Spiders | The Binding of Isaac: Repentance | 1,313 | | The Binding of Isaac: Rebirth
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| 412. | The Floor 1 Win | The Binding of Isaac: Repentance | 1,312 | | The Binding of Isaac: Rebirth
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| 413. | I was short on Time and the Game HEARD ME | The Binding of Isaac: Repentance | 1,312 | | The Binding of Isaac: Rebirth
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| 414. | MISSILE BOMBS require some good Defenses | The Binding of Isaac: Repentance | 1,311 | | The Binding of Isaac: Rebirth
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| 415. | Angelic Brimflection | The Binding of Isaac: Repentance | 1,311 | | The Binding of Isaac: Rebirth
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| 416. | "This is not a Vanishing Twin run..." | The Binding of Isaac: Repentance | 1,309 | | The Binding of Isaac: Rebirth
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| 417. | Twisted Pair leads to the WILDEST Tear Builds | 1,309 | | The Binding of Isaac: Rebirth
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| 418. | Dream Build | The Binding of Isaac: Repentance | 1,308 | | The Binding of Isaac: Rebirth
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| 419. | I tried out BUFFED ABYSS so you don't have to | The Binding of Isaac: Repentance | 1,305 | | The Binding of Isaac: Rebirth
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| 420. | My FAVOURITE Angel Item loves HOMING | The Binding of Isaac: Repentance | 1,303 | | The Binding of Isaac: Rebirth
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| 421. | Bargain | The Binding of Isaac: Repentance | 1,302 | | The Binding of Isaac: Rebirth
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| 422. | Rollercoaster | The Binding of Isaac: Repentance | 1,300 | | The Binding of Isaac: Rebirth
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| 423. | Just Add Damage | The Binding of Isaac: Repentance | 1,298 | | The Binding of Isaac: Rebirth
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| 424. | Rebirth - 7:25 Normal Mode Chest Run (Personal Best) | 1,298 | |
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| 425. | Ultimate Saturnus | The Binding of Isaac: Repentance | 1,298 | | The Binding of Isaac: Rebirth
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| 426. | Treasure Hunter | The Binding of Isaac: Repentance | 1,296 | | The Binding of Isaac: Rebirth
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| 427. | I took LIBRA and it was kinda GREAT | The Binding of Isaac: Repentance | 1,293 | | The Binding of Isaac: Rebirth
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| 428. | The Cat and the Combo | The Binding of Isaac: Repentance | 1,289 | | The Binding of Isaac: Rebirth
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| 429. | Adding some Lasers to my Lasers | 1,288 | | The Binding of Isaac: Rebirth
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| 430. | This run was just RIDICULOUS | The Binding of Isaac: Repentance | 1,288 | | The Binding of Isaac: Rebirth
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| 431. | Build almost went TOO HARD | 1,285 | | The Binding of Isaac: Rebirth
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| 432. | When you play Greed Mode and these show up | 1,282 | | The Binding of Isaac: Rebirth
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| 433. | "Luck Down" | The Binding of Isaac: Repentance | 1,281 | | The Binding of Isaac: Rebirth
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| 434. | Bouncy Ball Bath | 1,281 | | The Binding of Isaac: Rebirth
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| 435. | Sacred Sword | 1,281 | | The Binding of Isaac: Rebirth
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| 436. | Double the Triple | The Binding of Isaac: Repentance | 1,278 | | The Binding of Isaac: Rebirth
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| 437. | Incubus leads to the MOST FUN Tear Builds! | 1,277 | | The Binding of Isaac: Rebirth
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| 438. | Maybe I shouldn't | The Binding of Isaac: Repentance | 1,277 | | The Binding of Isaac: Rebirth
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| 439. | PROPTOSIS is the best and worst Item at the same time | The Binding of Isaac: Repentance | 1,273 | | The Binding of Isaac: Rebirth
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| 440. | Cat goes Boom | The Binding of Isaac: Repentance | 1,270 | | The Binding of Isaac: Rebirth
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| 441. | Stats aren't everything | The Binding of Isaac: Repentance | 1,270 | | The Binding of Isaac: Rebirth
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| 442. | How to win a run in 28 seconds | The Binding of Isaac: Repentance #shorts | 1,268 | Guide | The Binding of Isaac: Rebirth
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| 443. | Some Runs Just Have It All 5 | The Binding of Isaac: Repentance | 1,266 | | The Binding of Isaac: Rebirth
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| 444. | This Sword SAVED my Build and WRECKED my Hand | The Binding of Isaac: Repentance | 1,265 | | The Binding of Isaac: Rebirth
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| 445. | Not Mush Room For Improvement | The Binding of Isaac: Repentance | 1,265 | | The Binding of Isaac: Rebirth
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| 446. | I brought some Fetuses to MOTHER | The Binding of Isaac: Repentance | 1,264 | | The Binding of Isaac: Rebirth
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| 447. | Brimstone at Home | The Binding of Isaac: Repentance | 1,262 | | The Binding of Isaac: Rebirth
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| 448. | Filling the Room with TEARS | 1,262 | | The Binding of Isaac: Rebirth
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| 449. | Plop Goes the Kidney Stone | The Binding of Isaac: Repentance | 1,261 | | The Binding of Isaac: Rebirth
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| 450. | Everyone had to BAND TOGETHER to win this MOTHER run | The Binding of Isaac: Repentance | 1,261 | | The Binding of Isaac: Rebirth
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| 451. | Finally an OP Run again | The Binding of Isaac: Repentance | 1,260 | | The Binding of Isaac: Rebirth
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| 452. | It's this debate again | 1,260 | | The Binding of Isaac: Rebirth
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| 453. | When you keep finding great Items | The Binding of Isaac: Repentance | 1,260 | | The Binding of Isaac: Rebirth
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| 454. | This Combo is ABSURD | The Binding of Isaac: Repentance | 1,257 | | The Binding of Isaac: Rebirth
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| 455. | Pencil takes Tear Builds to the NEXT LEVEL | 1,256 | | The Binding of Isaac: Rebirth
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| 456. | Do THIS to get the most out of your EARLY FLOORS! | The Binding of Isaac: Repentance | 1,255 | | The Binding of Isaac: Rebirth
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| 457. | This DELIRIUM Run turned into a MOVIE | 1,254 | | The Binding of Isaac: Rebirth
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| 458. | Itsy Bitsy Tearspam | The Binding of Isaac: Repentance | 1,254 | | The Binding of Isaac: Rebirth
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| 459. | Fastest BOSS RUSH Clear I've EVER Done | The Binding of Isaac: Repentance | 1,254 | | The Binding of Isaac: Rebirth
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| 460. | My FAVOURITE kind of Build | The Binding of Isaac: Repentance | 1,254 | | The Binding of Isaac: Rebirth
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| 461. | My Most Absurd GOD HEAD Build this Year | 1,253 | | The Binding of Isaac: Rebirth
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| 462. | The CRAZIEST room drop | The Binding of Isaac: Repentance #shorts | 1,253 | | The Binding of Isaac: Rebirth
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| 463. | Tech X makes every build INSANE | The Binding of Isaac: Repentance | 1,252 | | The Binding of Isaac: Rebirth
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| 464. | Always great when your favourites come together | 1,248 | | The Binding of Isaac: Rebirth
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| 465. | Photogenic | The Binding of Isaac: Repentance | 1,248 | | The Binding of Isaac: Rebirth
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| 466. | Tear Spam, but at what cost? | The Binding of Isaac: Repentance | 1,248 | | The Binding of Isaac: Rebirth
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| 467. | Flies and Spiders | The Binding of Isaac: Repentance | 1,245 | | The Binding of Isaac: Rebirth
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| 468. | The Best of Friends | The Binding of Isaac: Repentance | 1,245 | | The Binding of Isaac: Rebirth
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| 469. | I tried out BUFFED Star of Bethlehem | The Binding of Isaac: Repentance | 1,244 | | The Binding of Isaac: Rebirth
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| 470. | Still the Best | The Binding of Isaac: Repentance | 1,240 | | The Binding of Isaac: Rebirth
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| 471. | Flood of Destruction | The Binding of Isaac: Repentance | 1,239 | | The Binding of Isaac: Rebirth
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| 472. | The EZ Game Mushroom | The Binding of Isaac: Repentance | 1,238 | | The Binding of Isaac: Rebirth
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| 473. | When it's a ONE HEART Start but You have a Dice | The Binding of Isaac: Repentance | 1,237 | | The Binding of Isaac: Rebirth
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| 474. | Crowned | The Binding of Isaac: Repentance | 1,235 | | The Binding of Isaac: Rebirth
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| 475. | Baby Tears. Literally. | The Binding of Isaac: Repentance | 1,233 | | The Binding of Isaac: Rebirth
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| 476. | Most BROKEN Start EVER | The Binding of Isaac: Repentance | 1,233 | | The Binding of Isaac: Rebirth
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| 477. | I found my FAVOURITE Item and DESTROYED everything | The Binding of Isaac: Repentance | 1,230 | | The Binding of Isaac: Rebirth
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| 478. | One of *those* runs | 1,229 | |
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| 479. | My First Online Run was a BANGER | The Binding of Isaac: Repentance | 1,223 | | The Binding of Isaac: Rebirth
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| 480. | The KINGS of CLUTCH! | The Binding of Isaac: Repentance | 1,223 | | The Binding of Isaac: Rebirth
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| 481. | This Start was SCARY... For one Room | The Binding of Isaac: Repentance | 1,222 | | The Binding of Isaac: Rebirth
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| 482. | I had to work for this one | 1,221 | | The Binding of Isaac: Rebirth
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| 483. | Close | The Binding of Isaac: Repentance | 1,220 | | The Binding of Isaac: Rebirth
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| 484. | Bounce | The Binding of Isaac: Repentance | 1,216 | | The Binding of Isaac: Rebirth
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| 485. | Literal Backstabbing | The Binding of Isaac: Repentance | 1,213 | | The Binding of Isaac: Rebirth
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| 486. | I started with it. | The Binding of Isaac: Repentance | 1,213 | | The Binding of Isaac: Rebirth
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| 487. | Scythes Everywhere! | The Binding of Isaac: Repentance | 1,210 | | The Binding of Isaac: Rebirth
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| 488. | All of these CARRIED this in the end | The Binding of Isaac: Repentance | 1,209 | | The Binding of Isaac: Rebirth
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| 489. | Technicality | The Binding of Isaac: Repentance | 1,208 | | The Binding of Isaac: Rebirth
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| 490. | You know it's bad when you rely on this guy | The Binding of Isaac: Repentance | 1,207 | | The Binding of Isaac: Rebirth
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| 491. | Tiny Planet to MOTHER | The Binding of Isaac: Repentance | 1,206 | | The Binding of Isaac: Rebirth
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| 492. | Milk and Cookies | The Binding of Isaac: Repentance | 1,203 | | The Binding of Isaac: Rebirth
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| 493. | This Rift Synergy goes HARD | The Binding of Isaac: Repentance | 1,202 | | The Binding of Isaac: Rebirth
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| 494. | Surely this makes Guppy, right? | 1,202 | | The Binding of Isaac: Rebirth
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| 495. | Royalty | The Binding of Isaac: Repentance | 1,201 | | The Binding of Isaac: Rebirth
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| 496. | Cyclops Pee | The Binding of Isaac: Repentance | 1,200 | | The Binding of Isaac: Rebirth
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| 497. | Star of the Show | The Binding of Isaac: Repentance | 1,199 | | The Binding of Isaac: Rebirth
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| 498. | Bigger Brim | The Binding of Isaac: Repentance | 1,198 | | The Binding of Isaac: Rebirth
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| 499. | Don't make this MISTAKE when trying to go to THE BEAST | The Binding of Isaac: Repentance | 1,197 | | The Binding of Isaac: Rebirth
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| 500. | Can you beat Isaac with only Quality 1 items? | 1,195 | | The Binding of Isaac: Rebirth
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