Top 100 The Binding of Isaac: Rebirth Videos With The Longest Duration by Player1up
| Video Title | Duration | Category | Game | |
|---|---|---|---|---|
| 1. | The Binding of Synthwave: Rewind | 52:45 | The Binding of Isaac: Rebirth | |
| 2. | "Repentance makes it impossible to get really strong runs" | 7:32 | The Binding of Isaac: Rebirth |