| 101. | Otterpop Reacts! to South Park Season 5 Episode 7 (Proper Condom Use) | 2,308 | |
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| 102. | Otterpop Reacts! to South Park Season 5 Episode 6 (Cartmanland) | 2,296 | |
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| 103. | Otterpop Reacts! to South Park Season 4 Episodes 14 & 15 | 2,294 | Show |
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| 104. | Otterpop Reacts! to South Park Season 3 Episode 5 (Tweek vs. Craig) | 2,272 | Show |
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| 105. | Otterpop Reviews! South Park Season 6 Episode 6 (Professor Chaos) | 2,233 | Review |
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| 106. | Otterpop Reacts! to South Park Season 4 Episode 6 (Cherokee Hair Tampons) | 2,224 | |
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| 107. | Otterpop Reviews! South Park Season 7 Episode 9 (Christian Rock Hard) | 2,214 | Review |
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| 108. | Forensic Science Major Analyzes! CSI: Crime Scene Investigation Season 1 Episode 7 (Blood Drops) | 2,207 | | CSI: Crime Scene Investigation
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| 109. | Otterpop Reacts! to South Park Season 3 Episode 8 (Two Naked Guys In A Hot Tub) | 2,203 | Show |
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| 110. | Otterpop Reacts! to SP Season 2 Episode 17 (Highlights) | 2,192 | Show |
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| 111. | Otterpop Reacts! to SP Season 2 Episode 12 (Highlights) REUPLOAD......again | 2,187 | Show |
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| 112. | Otterpop Reacts! to Despacito (Luis Fonsi ft. Daddy Yankee) and Pokécito (ThePopushi ft. Eric H.) | 2,187 | |
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| 113. | Otterpop Reviews! South Park Season 7 Episode 12 (All About Mormons) | 2,185 | Review |
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| 114. | Otterpop Reviews! South Park Season 7 Episode 2 (Krazy Kripples) | 2,185 | Review |
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| 115. | Otterpop Reacts! to South Park Season 3 Episode 17 (World Wide Recorder Concert) | 2,175 | Show |
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| 116. | Otterpop Reacts! to SP Season 2 Episode 18 (Highlights) | 2,150 | Show |
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| 117. | Otterpop Reacts! to South Park Season 4 Episode 1 (The Tooth Fairy's Tats 2000) | 2,145 | |
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| 118. | Otterpop Reviews! South Park Season 6 Episode 12 (A Ladder to Heaven) | 2,143 | Review |
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| 119. | Otterpop Reacts! to South Park Season 4 Episode 11 (Fourth Grade) | 2,132 | |
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| 120. | Otterpop Reviews! South Park Season 6 Episode 8 Review (Red Hot Catholic Love) | 2,125 | Review |
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| 121. | Otterpop Reacts! to Markiplier's TNTL Challenge 22 (plus my sister) | 2,110 | |
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| 122. | Otterpop Reviews! South Park Season 6 Episode 4 (Fun With Veal) | 2,105 | Review |
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| 123. | Otterpop Reacts! to SP Season 2 Episode 8 (Highlights) | 2,097 | Show |
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| 124. | Otterpop Reacts! to South Park Season 4 Episode 2 (Cartman's Silly Hate Crime 2000) | 2,097 | |
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| 125. | Otterpop Reacts! to South Park Season 5 Episode 12 (Here Comes The Neighborhood) | 2,088 | Show |
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| 126. | Otterpop Reviews! South Park Season 7 Episode 6 (Lil' Crime Stoppers) | 2,077 | Review |
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| 127. | Otterpop Reacts! to South Park Season 5 Episode 1 (It Hits the Fan) | 2,070 | |
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| 128. | Otterpop Reacts! to SP Season 2 Episode 10 (Highlights) | 2,067 | Show |
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| 129. | Otterpop Reviews! South Park Season 7 Episode 11 (Casa Bonita) | 2,055 | Review |
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| 130. | Otterpop Reviews! South Park Season 8 Episode 6 (The Jeffersons) | 2,047 | Review |
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| 131. | Otterpop Reviews! South Park Season 7 Episode 5 (Fat Butt and Pancake Head) | 2,043 | Review |
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| 132. | Otterpop Reacts! to South Park Season 3 Episode 2 (Spontaneous Combustion) | 2,012 | |
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| 133. | Otterpop Reacts! to SP Season 2 Episode 13 (Highlights) REUPLOAD | 2,010 | Show |
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| 134. | Otterpop Reacts! to SP Season 2 Episode 15 (Highlights) | 2,010 | Show |
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| 135. | Otterpop Reacts! to South Park Season 3 Episode 12 (Hooked on Monkey Fonics) | 2,009 | Show |
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| 136. | Merry Christmas! plus reacting to South Park Season 3 Episode 15 (Mr. Hankey's Christmas Special) | 2,002 | |
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| 137. | Otterpop Reviews! Dan Vs The Wolfman (Season 1 Episode 1) | 1,996 | Review |
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| 138. | Otterpop Reviews! South Park Season 7 Episode 7 (Red Man's Greed) | 1,980 | Review |
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| 139. | Otterpop Reacts! to South Park Season 3 Episode 3 (The Succubus) | 1,968 | Show |
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| 140. | Otterpop Reacts! to SP Season 2 Episode 9 (Highlights) REUPLOAD | 1,952 | Show |
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| 141. | Otterpop Reviews! South Park Season 6 Episode 5 (The New Terrance and Phillip Movie Trailer) | 1,951 | Review |
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| 142. | Otterpop Reviews! South Park Season 6 Episode 16 (My Future Self 'n' Me) | 1,942 | Review |
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| 143. | Otterpop Reviews! South Park Season 7 Episode 4 (I'm A Little Bit Country) | 1,935 | Review |
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| 144. | Otterpop Reviews! South Park Season 8 Episode 2 (Up The Down Steroid) | 1,934 | Review |
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| 145. | Best Moments | Jacksepticeye plays The Last Guardian, Part 2 | 1,928 | Let's Play | The Last Guardian
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| 146. | Otterpop Reacts! to South Park Season 3 Episode 7 (Cat Orgy) | 1,888 | |
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| 147. | Otterpop Reacts! to South Park Season 5 Episode 8 (Towelie) | 1,876 | |
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| 148. | Otterpop Reacts! to South Park Season 10 Episodes 3 & 4 (Cartoon Wars) | 1,876 | | Cartoon Wars
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| 149. | Otterpop Reviews! South Park Season 7 Episode 3 (Toilet Paper) | 1,865 | Review |
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| 150. | Otterpop Reacts! to South Park Season 3 Episode 14 (The Red Badge of Gayness) | 1,862 | |
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| 151. | Otterpop Reviews! South Park Season 8 Episode 7 (Goobacks) | 1,848 | Review |
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| 152. | Otterpop Reviews! South Park Season 7 Episode 13 (Butt Out) | 1,845 | Review |
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| 153. | Otterpop Reviews! South Park Season 8 Episode 9 (Something Wall-Mart This Way Comes) | 1,838 | Review |
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| 154. | Otterpop Reacts! to SP Season 2 Episode 16 (Highlights) | 1,835 | Show |
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| 155. | Otterpop Reacts! to South Park Season 4 Episode 12 (Trapper Keeper) | 1,833 | Show |
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| 156. | Otterpop Reviews! South Park Season 9 Episode 4 (Best Friends Forever) | 1,826 | Review |
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| 157. | Otterpop Reviews! South Park Season 8 Episode 4 (You Got F'd in the A) | 1,826 | Review |
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| 158. | Otterpop's Best Gaming Moments of 2020! | 1,818 | |
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| 159. | Otterpop Reacts! to South Park Season 3 Episode 6 (Sexual Harrassment Panda) | 1,817 | |
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| 160. | Otterpop Reviews! South Park Season 6 Episode 2 (Asspen) | 1,805 | Review |
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| 161. | Otterpop Reacts! to South Park Season 4 Episode 3 (Timmy 2000) | 1,803 | Show |
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| 162. | Otterpop Reacts! to @watcher's Puppet History: The Dancing Plague (patron request!) | 1,801 | |
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| 163. | Otterpop Reacts! to South Park Season 5 Episode 11 (The Entity) | 1,801 | | The Entity
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| 164. | Otterpop Reviews! South Park Season 9 Episode 5 (The Losing Edge) | 1,792 | Review |
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| 165. | Otterpop Reacts! to @SpindleHorse's Helluva Boss Season 2 Episode 2 (Seeing Stars) | 1,780 | Show |
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| 166. | Otterpop Reacts! to South Park Season 5 Episode 5 (Terrence and Phillip: Behind the Blow) | 1,777 | Show |
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| 167. | Otterpop Reacts! to South Park Season 4 Episode 4 (Quintuplets 2000) | 1,767 | |
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| 168. | Otterpop Reviews! South Park Season 6 Episode 3 (Freak Strike) | 1,765 | Review |
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| 169. | Otterpop Reviews! South Park Season 8 Episode 5 (AWESOM-O) | 1,755 | Review |
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| 170. | Otterpop Reviews! South Park Season 6 Episode 9 (Free Hat) | 1,742 | Review |
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| 171. | Jacksepticeye Curse and Rage Compilation | Golf With Friends | 1,699 | | Golf With Your Friends
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| 172. | Otterpop Reacts! to South Park Season 10 Episode 7 (Tssst) | 1,697 | Show |
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| 173. | Otterpop Best Moments in Subnautica, Part 2 | 1,690 | | Subnautica
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| 174. | Otterpop Reacts! to South Park Season 3 Episode 4 (Jakovasaurs) + Quick November Update | 1,668 | Vlog | South Park
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| 175. | Otterpop Reacts! to South Park Season 3 Episode 9 (Jewbilee) | 1,666 | Show |
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| 176. | Otterpop Reviews! South Park Season 8 Episode 11 (Quest for Ratings) | 1,590 | Review |
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| 177. | Otterpop Reviews! South Park Season 7 Episode 10 (Grey Dawn) | 1,585 | Review |
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| 178. | Otterpop Reacts! to South Park Season 4 Episode 13 (Helen Keller! The Musical) | 1,577 | |
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| 179. | Otterpop Reacts! to South Park Season 3 Episode 13 (Starvin' Marvin in Space) | 1,556 | |
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| 180. | Otterpop Reacts! to Markiplier's Try Not to Laugh 15 Challenge | 1,487 | |
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| 181. | Otterpop Reviews! South Park Season 9 Episode 2 (Die Hippie, Die) | 1,431 | Review |
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| 182. | Otterpop Reviews! South Park Season 8 Episode 13 (Cartman's Incredible Gift) | 1,424 | Review |
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| 183. | Otterpop Reviews! South Park Season 8 Episode 8 (Douche and Turd) | 1,412 | Review |
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| 184. | Otterpop Reviews! to South Park Season 9 Episode 3 (Wing) | 1,400 | Review |
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| 185. | About South Park Season 8 Episode 14 | 1,305 | |
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| 186. | Otterpop Reacts! to South Park Season 10 Episode 6 (ManBearPig) | 1,283 | |
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| 187. | Otterpop Reacts! to South Park Season 10 Episode 1 (The Return of Chef) | 1,269 | |
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| 188. | Otterpop Reacts! to Markiplier's Try Not to Laugh Challenge 19 | 1,246 | |
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| 189. | Discussing My Favorite South Park Episodes! (Seasons 1-5) | 1,244 | Show |
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| 190. | Otterpop Reacts! to South Park Season 10 Episode 2 (Smug Alert!) | 1,233 | |
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| 191. | Otterpop Reacts! to @watcher's Puppet History: Hatshepsut, The Forgotten Pharoah (patron request!) | 1,220 | |
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| 192. | Otterpop's Best Moments in Subnautica | 1,209 | | Subnautica
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| 193. | About South Park Season Episode 9... | 1,133 | |
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| 194. | About South Park Season 8 Episode 13 | 1,084 | |
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| 195. | Otterpop Reacts! to South Park Season 10 Episode 8 (Make Love, Not Warcraft) | 1,060 | Show |
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| 196. | Otterpop Reacts! to Markiplier's Try Not to Laugh Challenge 8 | 993 | |
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| 197. | A South Park Season Eight Update! | 973 | |
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| 198. | Otterpop Reacts! to Jingai-san no Yome (Patron Request!) | 972 | |
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| 199. | Forensic Science Major Analyzes! @Wendigoon Video on the Terror behind The Lost Franklin Expedition | 970 | |
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| 200. | Otterpop Reacts! to Markiplier's Try Not to Laugh Challenge 14 | 934 | |
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